Muscle Twitches and Other Problems From Sublingual Bupe

[allecw]

I am trying as hard as I can to switch from snorting bupe to taking it sublingual yet it just seems like a totally different drug.

When I snort it I just feel normal. Nothing great but I feel normal. When I take it sublingually I just don't feel right

For starters every time I take my subs sublingually I get these weird muscle twitches. Mainly in my legs but every time I get them. It doesn't hurt but why is it happening?

Also I feel all kind of spaced out when I take the subs sublingually. My head feels detached and my eyes feel all weird. The only time i have gotten positive results from sublingual use if if I also snort some before.

I'm not going through opiate withdrawal or anything but I feel anything but stable. I don't feel like I can function when I take them sublingually.

Do I just have to get used to switching over from snorting? I have tried more to make up for the lower ba and nothing except for feeling weird.

It has to have the same effects no matter how it is taken right? If I get the dosage right. I mean it can't be a totally different drug just because it is taken differently right?

I almost feel like I am not doing the sublingual thing right. I have left it under my tounge for thirty minutes and nothing. I do have a problem within lot of saliva collecting in my mouth. Could that be causing my problems?

I remember the first ever time I took subs it was sublingual and 4mg knocked me out for the day. Actually any sublingual dose would knock me out at first no matter how small the dose. That's why I started snorting them. It was the only way I could take them. They were too strong sublingual and just right snorted. Now a year later i get nothing from sublingual when it used to effect me more than snorting?

Again has anyone heard of subs causing muscle twitches? I take klonopin with them and that seems to help but why the twitches?

Any advice for switching from snorting to sublingual? Is a lot of this possibly in my head?

 

[Acidtek]

They are actuallly stronger if you snort them, don't really know know what the twitching thing is about but if it's causing you no pain I wouldn't really worried about it, it could just be your body adjusting from the dosage ba of snorting to the ba of sublingual, give it a week and it should even itself out

 

[NeighborhoodThreat]

The twitching is a strange side effect is something I haven't heard of before, but Acidtek is exactly right, buprenorphine's BA is higher via the snorting route than it is via the sublingual route, and because buprenorphine is a very potent drug in terms of dosage, even a small change in dosage can make a big difference.

 

[likeakite]

Twitching does happen to me when I take Narcs, Klonopin does help. I think muscle twitching is a side effect of most Narcs esp Tramadol.

 

[allecw]

Can't I up my buprenorphine dose to match?

Like I was taking 4 mg a day. Couldn't I just take 5-6 mg a day sublingual and it would even out?

I have tried this and still do not get the same effects as when I snort them. If it is just the ba that is different shouldn't taking more work?

Are there factors other than ba when snorting that could be making the difference here. It just doesn't seem like the same drug when I take it sublingually.

My only guess is that I am so used to snorting them it's going to take me a while to get used to taking them sublingually.

Like yesterday for instance I went the whole day taking the subs sublingually and just felt spaced out weird with o emotions. Well right before night time I decided to snort a small amount. Right when I snorted that small amount I felt better. I didn't feel completely normal but I all the sudden felt a little less out of it.

In those few seconds after snorting the subs I know it didn't have time to have any real effect. So now I am assuming a lot of this is mental. Not all mental but some.

I assume that if someone got used to snorting oxy for a year or so without ever taking it any other way and then decided to start taking it orally they might not think it is working as well when infact it might be working better.

I definitely don't feel like I'm addicted to the act of snorting but that must be what's going in here. I imagine it is much worse for people who shoot stuff.

 

[effie]

There could be quite a large psychological component, even if you aren't hooked on snorting - you might be anxious before you take them sublingually now, and expect a different response.. there is a huge overlap between body and mind so it isn't that strange for your state of mind and thoughts about a ROA to affect the response you get, especially for something like bupe which I feel can be quite subtle and subjective at times.

I'd presume it is that, combined with the lower bioavailability.. many drugs feel completely different at low doses and higher doses, and although opioids aren't typical for that, bupe is an atypical opioid so that might account for some of the variation too..

Some drugs have different effects snorted compared to swallowed because the swallowed drugs are shunted straight off to the liver, but sublingual and snorted both rely on swift absorption into the bloodstream..

I think you've got it pretty sussed actually, reading your last post

 

[paper planes]

ive been on suboxone for almost 2 yrs now and ive been on alot of different doses when i tried it recreationally i snorted it and for a couple weeks after i was prescribed but eventually i got more out of the subl. route....but from personal experiece try lowering your dose to around 2 mgs and get used to it, it may take a week or so but it will be better in the long run ...also have you tried the alcohol solution becuase they greatly improves the bioavailability

 

[unsettled]

I've gone back and forth from the strips to the tabs and I feel that I get more out of the tabs over all. With the tabs I can snort small amounts and feel energized as well as very calm, they also last longer for me. The strips are very sedating for me, I like them but they don't last as long and once I've opened one it seems to lose potency (this may be placebo).

I definitely feel that I get more out of the tabs overall though, however if you're switching over from another opiate to bupe I think I'd prefer the strips since they are much more sedating to me. I do like the convenience factor of the strips.

I guess if you could have both that would be ideal, but since I can only have one I choose the pills too. It may be a psychological thing with the snorting, the whole ritual, but I do like the energizing effect and how I can make them last twice as long.