C) try to be helpful when you post here please.
The best ROA depends on a few things, cygnus. Oral is the safest way to consume pills (crush if it is MSContin or other ER preparations) but morphine has a pretty low oral bioavailability (around 30%.) Plugging it (rectal administration) has a higher bioavailability (between 30% and 60%, seen different figures) and is also a pretty safe ROA. Don't snort it; insufflated it only has a 15-20% bioavailability. IV of course has 100% but is extremely unsafe, especially for pills, and especially something waxy like MSContin.