Most uses of medical marijuana wouldn't pass FDA review, study finds

slimvictor

slimvictor

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If medical marijuana were a regular drug, it would need the blessing of the Food and Drug Administration before it could be prescribed to patients. And in most cases, those patients would be out of luck.

A comprehensive review of dozens of clinical trials that have tested medical marijuana for 10 conditions finds that there’s very little reliable evidence to support the drug’s use. The review, by an international team of researchers, was published Tuesday in the Journal of the American Medical Assn.

Patients who use medical marijuana to treat chronic neuropathic pain or cancer pain would probably have the least to fear from an FDA review. The JAMA study considered 28 studies involving 2,454 patients and concluded that there was “moderate-quality evidence” from at least a dozen studies showing that cannabinoids – chemicals in marijuana that produce pharmacologic effects inside the body – reduced pain in such patients by modest amounts.

However, trials testing the pain-relieving effects of medical marijuana in people with fibromyalgia, HIV-associated sensory neuropathy, rheumatoid arthritis, multiple sclerosis and other conditions did not show that it worked.

cont at
http://www.latimes.com/science/sciencenow/la-sci-sn-medical-marijuana-review-20150623-story.html
 
I guess who really cares what the bloody FDA says. Lol.. arent they funded by the very big pharma they 'regulate"

Its amazing to look at the pathedic difference between a sugar pill and the crap they aprove.

Maybe the fucking fda should make it illegal to advertise their aproved garbage on tv.. it seems to be every other comercial.

We should all play a smoking game tonight. Everytime a drug comercial comes on we all havr to take a dab.. lol it would be a short game.
 
Fda stands for fucking dat ass. They have been fucking ppl over for years. And who cares what they say does and doesn't work. What may work for one person may not be as effective or work at all for someone e else.

I've been getting migraines for 20 some years and one of the few things that alleviates the nausea pain light sensitivity and everything else...plus it helps me get to sleep. Its not aograine panacea, I still have to take an immitrex if its really bad, but being able to smoke makes it so much more bearable.

If they ever legalize for medical here in MD Im sure I could get one for migraines, I have decades of documentation.
 
The cannabinoids in marijuana have legitimate medical uses. The complication is legitimate medical research is almost impossible. The study demonstrates scientist can't preform legitimate research. This doesn't prove medical marijuana is ineffective.

In the United States medical marijuana research previously required DEA schedule I licensing, Public Health Service review, and FDA approval. Furthermore the marijuana used in research is only supplied through NIDA (National Institute on Drug Abuse) and was low potency brick weed.

These regulations severely impede medical marijuana research and this is absurd. Research on heroin has fewer restrictions than research on marijuana.

The situation is improving 'medicine cabinet' and in the future research should support the observations of marijuana's benefits you, other people, and myself have noted. Recently NIDA began growing mid grade marijuana and the Public Health Service review was eliminated. Legitimate medical marijuana research requires additional change. Future research is heavily influenced by government barriers.
 
This doesn't matter in the slightest. As long as the FDA approves a drug for ANY one indication a doctor can choose to prescribe it for whatever the hell they want. Doctors prescribe pharmaceuticals off-label all the time without any proof of efficacy, why should we hold marijuana to a higher standard?
 
^To play Devil's Advocate here, I would argue that marijuana simply isn't like other approved drugs and that it in fact diverges quite well from any other prescribed medicine. Nothing approved directly causes action at CB1/2 receptors. It's also a hallucinogen which can produce a heightened emotional dysphoria after even a little use; I don't recall any approved medicines which can do that so readily. I think furthermore there have been studies demonstrating its negative effect on the adolescent brain. Alcohol can definitely do this, but the variety of ills, such as depression, insomnia, psychotic disorders, decreased intelligence, etc, so not manifest after moderate alcohol usage, whereas they have been documented in cannabis use which isn't excessive. So there's those things...

As a medicine my opinion is that it should definitely be used instead of opiates in many cases due to addiction, but in a growing brain, if even half of the studies documenting detrimental abuse on the growing brain have discovered something resembling causation, I would say that it's not a good idea unless literally nothing else works (as is the case with many epileptic children).

Unfortunately, the world is still being subjected to really harsh rules when it comes to hallucinogens, including marijuana. Very few trials can get conducted because of all the red tape. I wanted to suggest that when all of the cannbinoids are isolated and carefully analyzed in in-vitro as well as in-vivo studies, then we can better say what chemical does what. Giving someone marijuana these days is sadly akin to giving them a mystery-box--no one really knows what any one of the tens of compounds in it does what, even if THC and CBD and CBN percentages are known, there are still dozens of chemicals in there that haven't been properly assessed. Here I might draw an analogy to cigarettes--it's true that we don't know what many of the compounds in commercial tobacco do beyond increasing its addictive quality; where this analogy stops is that cigarettes don't cause HPPD, bad trips, or as drastic (at least) a change to the mind/brain. It's prudent to assume because of this that many chemicals in marijuana are quite powerful.

What doesn't make sense to me is why governments are dragging their feet in isolating every compound (of natural origin) typically found in marijuana. I guess I would chalk it up to too much pharmaceutical-corporate money swaying politicians in favor of approving substances which can make people a lot of money. The reality does kind of suck for someone like me who could quite possibly benefit from cannabinoids, but it just sucks donkey nuts for epileptic kids. Jeez, when it's gotten to the point of having tens of seizures a day or not, all of which could involve a broken neck, biting off one's tongue and choking, or other potential harms, I say give the damn kid their marijuana if it helps more than anything else.
 
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