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Most effective way to take LSD
- Thread starter Twicegone
- Start date
slimvictor
Bluelight Crew
^ yep. Don't ever, ever put anything into your eye, apart from eye drops. There are no conceivable benefits, but there are many risks.
(assuming that you take them together) If you take more LSD, the trip - not just the visuals, which I consider a minor part of the trip, but the entire experience, including the emotional and psychological aspects - intensifies. You will probably stay awake a bit longer, but the difference will likely only be an hour or two, if you are comparing one tab and two . Once you get to 3 or 4 tabs of average strength LSD, the length of the trip will likely be extended by 3 hours or more (as compared to a single tab).
If you stagger the doses, the intensity may not change much, but the length of the trip will increase (so you can't sleep for much longer).
(assuming that you take them together) If you take more LSD, the trip - not just the visuals, which I consider a minor part of the trip, but the entire experience, including the emotional and psychological aspects - intensifies. You will probably stay awake a bit longer, but the difference will likely only be an hour or two, if you are comparing one tab and two . Once you get to 3 or 4 tabs of average strength LSD, the length of the trip will likely be extended by 3 hours or more (as compared to a single tab).
If you stagger the doses, the intensity may not change much, but the length of the trip will increase (so you can't sleep for much longer).
3rd_I_blind
Bluelighter
Putting anything in your eye will always produce some irritation. Now imagine that irritation inceased ten- er twentyfold by the LSD... Besides that, common sense should already dictate this kind of stories belong in the same category as the spinal fluid/perpetual LSD in your brain bullshit.
For increased effectivity you can dose sublingually (although only feasible with liquid LSD) or use some of the other ROAs known to bypass first-pass metabolism. However, oral bioavailability is already 70-80 per cent, so personally I wouldn't bother with all that ruckus.
And as Slimvictor already said:
2 hits taken together = major increase in intensity, minor increase in duration
2 hits taken after eachtoher = minor increase in intensity, moderate increase in duration
For increased effectivity you can dose sublingually (although only feasible with liquid LSD) or use some of the other ROAs known to bypass first-pass metabolism. However, oral bioavailability is already 70-80 per cent, so personally I wouldn't bother with all that ruckus.
And as Slimvictor already said:
2 hits taken together = major increase in intensity, minor increase in duration
2 hits taken after eachtoher = minor increase in intensity, moderate increase in duration
helium-4
Bluelight Crew
Putting substances in your eye with an unknown purity is plain and simple idiocy. You could potentially lose your sight, or at the very least cause some irritation. Think about how fun it will be to be tripping balls, all the while being fixated on the irritation in your eye... So, plainly, DO NOT PUT DRUGS IN YOUR EYE UNLESS DIRECTED TO BY A PHYSICIAN OR IT IS INDICATED ON THE PACKAGING MATERIAL OF NON-ILLICIT DRUGS.
Some people report plugging LSD to be superior to oral or sublingual ingestion, so you might want to give that a try if you want to make the most out of your LSD, but really the bioavaliability is already relatively 100% of the dose to IV, for oral and sublingual. Reports of IV LSD seem to be mixed on a slight decrease in the time of the come up and no discernible change in timeline/dynamic, even, so I'd suggest just sticking to sublingual/oral dosing.
Increasing the dose of the LSD will only really increase the duration if the previous experienced dose with the same substance was toward the lighter end of the spectrum (8-10 hours potentially rather than 10-12 hours [+/- 2 hours] of a higher dose), or taken at a different time. Increasing the dose wont deviate far from its general depicted timeline, but it will obviously change the dynamic of the trip. How much of a change in experience is determined by the potency of the blotters along with a few other less significant factors (expectations, placebo, etc).
Some people report plugging LSD to be superior to oral or sublingual ingestion, so you might want to give that a try if you want to make the most out of your LSD, but really the bioavaliability is already relatively 100% of the dose to IV, for oral and sublingual. Reports of IV LSD seem to be mixed on a slight decrease in the time of the come up and no discernible change in timeline/dynamic, even, so I'd suggest just sticking to sublingual/oral dosing.
Increasing the dose of the LSD will only really increase the duration if the previous experienced dose with the same substance was toward the lighter end of the spectrum (8-10 hours potentially rather than 10-12 hours [+/- 2 hours] of a higher dose), or taken at a different time. Increasing the dose wont deviate far from its general depicted timeline, but it will obviously change the dynamic of the trip. How much of a change in experience is determined by the potency of the blotters along with a few other less significant factors (expectations, placebo, etc).
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3rd_I_blind
Bluelighter
Have any source to back that statement? Since afaik it is not true; it is actually around 70%.
Darksidesam
Bluelight Crew
Are you this man by any chance?
helium-4
Bluelight Crew
I thought it was higher than that, but yeah, pH within the GI tract as well as the stomach contents can alter the percentage of the LSDs initial dose that is distributed throughout the body. I looked and looked and all I found was http://www.maps.org/research/lsd/swisslsd/LDA1010707.pdf with a small section discussing bioavailability, giving 70% for p.o. absorption, but they don't really dive much into it. I don't see why sublingual wouldn't have a higher bioavailability than that though.
3rd_I_blind
Bluelighter
Well, a sublingual blotter will probably result in you swallowing lots and lots of saliva, meaning that the actual ROA is still oral intake. Unless you are talking about liquid LSD, then you could easily put a drop on your gums and let it rest there without excessive build-up of saliva.
I agree the MAPS report does not dive into it very deep, but nevertheless it is really uncommon for any substance to have a 100% bioavailability with oral intake. Especially when considering the intricate structure of LSD, and the proton in the 8-position that can change configuration (depending on pH; the small intestine is slightly alkaline) to yield iso-LSD - which is inactive.