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  • BDD Moderators: Keif’ Richards | negrogesic

Opioids Morphine

B

Binky7766

Bluelighter
Joined
Oct 25, 2021
Messages
140
Is 15 mgs of Morphine Oral (pill)
considered to be a high or low dose? I have an extremely high tolerance for opiates & was just prescribed this dose. I felt no euphoria and mild pain relief. The next day I tried two pills. Same. So I'm curious about the milligram dosage. For someone like me, what would be an effective dose? Again, this is the pill and not the IV (I wish!).

Also, is it true that sugar makes morphine a lot less effective? If so, does anyone know if it's a huge difference when combining with sugar?
 
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Super low. Assume 30% bioavailability for morphine. I don't really want to suggest plugging, I feel like it's demeaning and I personally wouldn't do it, but that does like double the bioavailability for this particularly. Morphine is actually like 1/3 stronger than oxycodone in terms of binding affinity and agonism, but our metabolism fucks us out of 70% of morphine orally. So oxy pills are about 3x stronger in reality than morphine pills. So expect them to feel like perc fives.
A few suggestions for potentiating the morphine:
DLPA is a phenethylamine stim which increases binding affinity to mu receptors (for enkalphins at least)
Blackseed oil
ULDN (strongest potentiator I know of)
Cats claw
Dxm
Clonidine
Corydalis
Lyrica (gabapentin further decreases absorption, so stay with pregabalin)
Promethazine, hydroxyzine, or other antihistamines
Agmatine
Caffeine increases analgesia from opioids.
Valerian&hops combo has a mild effect on mu receptors.
Curcumin&black pepper
Magnesium
Scullcap
You might also just want to start using a homemade kratom(or poppy?) syrup, unless perc fives would get you through with x script amount... dm me if you wanna know how.
 
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daturetard said:
Super low. Assume 30% bioavailability for morphine. I don't really want to suggest plugging, I feel like it's demeaning and I personally wouldn't do it, but that does like double the bioavailability for this particularly. Morphine is actually like 1/3 stronger than oxycodone in terms of binding affinity and agonism, but our metabolism fucks us out of 70% of morphine orally. So oxy pills are about 3x stronger in reality than morphine pills. So expect them to feel like perc fives.
A few suggestions for potentiating the morphine:
DLPA is a phenethylamine stim which increases binding affinity to mu receptors (for enkalphins at least)
Blackseed oil
ULDN (strongest potentiator I know of)
Cats claw
Dxm
Clonidine
Corydalis
Lyrica (gabapentin further decreases absorption, so stay with pregabalin)
Promethazine, hydroxyzine, or other antihistamines
Agmatine
Caffeine increases analgesia from opioids.
Valerian&hops combo has a mild effect on mu receptors.
Curcumin&black pepper
Magnesium
Scullcap
You might also just want to start using a homemade kratom(or poppy?) syrup, unless perc fives would get you through with x script amount... dm me if you wanna know how.
Click to expand...
Naw, that's ok, but thanks for offering! And that's a lot of valuable info, so thanks for taking the time on that. My Morphine is ER. Is that something that might stave off any euphoria?
 
What kind of morphine er pills do you have? If there the beads you can crush them. If they are mscontin style ones you need heat.
 
paranoid android said:
What kind of morphine er pills do you have? If there the beads you can crush them. If they are mscontin style ones you need heat.
Click to expand...
I only have access to MsContin I normally just chew them and suwhat dbl my dose but do not advise from a HR point of view. What you mean heat and what ROA then?
 
Binky7766 said:
Naw, that's ok, but thanks for offering! And that's a lot of valuable info, so thanks for taking the time on that. My Morphine is ER. Is that something that might stave off any euphoria?
Click to expand...
Well, yes, you'll probably be getting five milligrams every hour-2 or so with ers so they won't feel as good as getting the full dose at once, however, they'll last longer for pain relief. So yes, you can listen to the other folks and crush them, but if you do theyre less likely to last you until your next refill. Being in chronic pain in the US (I assume you're from) sucks. Morphine equivalent caps are absurd.
 
Preparing Morphine for injection is typically a difficult process. 99% of Morphine that I've ever encountered in North America has been controlled-release in some way. This lends an element of danger to the process. I wouldn't advise trying it due to the risks.

If you are looking for a higher bioavailability, your only real option with Morphine is going to be the rectal route. The available literature varies regarding the bioavailability. The general consensus is that it is approximately double the potency of oral administration. You will also experience a faster onset and, in my opinion, a more powerful high of a slightly different character (more of a body high).

Rectal administration is easy and generally safe, so I throw it out there whenever I can.

To answer your original question, 15mg Morphine is not a significant amount. This is what I would tell a completely Opioid-naive individual to start with if they were looking to experiment safely. I'm not sure what your tolerance actually looks like. The thing is that you're unlikely to get any significant effects from a dosage like this with any kind of tolerance.

Let us know if you have other questions. We will be here!
 
Binky7766 said:
I'm not sure what beads are , but they are small, purple, solid pill. Are beads like a soft gel ?
Click to expand...
Beads are little balls of medicine that are in many different pills. If it has a bunch of little dots and is a capsule, likelihood is its beads. What you're describing just sounds like a tablet, not a cap.
 
daturetard said:
Beads are little balls of medicine that are in many different pills. If it has a bunch of little dots and is a capsule, likelihood is its beads. What you're describing just sounds like a tablet, not a cap.
Click to expand...
Beads are inside of capsules not tablets,,the beads need to be crushed so they dissolve in water to be injected or boofed,,I believe sniffing is a waste of time with morphine,,I have a opioid tolerance and I shoot 300mg at a time
 
Just a little pinprick said:
Beads are inside of capsules not tablets,,the beads need to be crushed so they dissolve in water to be injected or boofed,,I believe sniffing is a waste of time with morphine,,I have a opioid tolerance and I shoot 300mg at a time
Click to expand...
That's literally what I said. Reread what i wrote. I mentioned tablets because that's what the poster seems to have, not because beads are in tablets.
By "different pills" I meant different pills of a like kind that are formulated into the same vague type of pill, though contain different active drugs.
 
daturetard said:
That's literally what I said. Reread what i wrote. I mentioned tablets because that's what the poster seems to have, not because beads are in tablets.
By "different pills" I meant different pills of a like kind that are formulated into the same vague type of pill, though contain different active drugs.
Click to expand...
Gotcha my bad,when someone says pills I instantly think of tablets,,,your comment make total sense….
 
The morphine by us is tablets as we only get MsContin here. When crushing those tabs, does one need to scrape of a layer of the tablet of something?
 
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