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  • BDD Moderators: Keif’ Richards

Morphine IV habit, followed by short Oxy IV, almost no WDs?!

ivnaut

Greenlighter
Joined
Oct 29, 2018
Messages
2
I have some good sources for pharmaceuticals. Recently I started using opioids again, Morphine Sulphate. My tolerance went up to 120mg+ IV /day, and then the supplier ran out. But I did get 280 mg of Oxynorm (IR Oxycodone), easy to prep for IV. The tolerance to that shot up *really* quickly in few days, like from 10 mg put me to heavy nods to 10 mg just keeping me OK for some hours in! So all the 280 mg was consumed in about 5 days. Now, I've been trying to stop using Morphine almost every weekend and holiday but the WDs (and PAWS, if I ever got so far) were such a bitch that I could just not resist and went back to my source for more. This time, after shooting all that Oxy, finishing at Friday evening - I was totally surprised that the WDs were almost nothing. Slight sweating/chills, Clonazepam 1 mg handled those easily. A bit of restless legs, Diazepam 10 mg handled that easily too. In the bedtime I do take a bit more massive amount of benzos + melatonin but actually slept OK. It is now Monday, and I can't believe it has been this easy. On Sunday I did not take any benzos until early evening and felt almost OK. Today I will try to be benzo-free until the night doses. What could explain this?! I know the half-life of MS is supposed to be 2h (based on wikipedia and other sources (not my experience)) and OC ~4-5h (based on wikipedia I think and other sources), which could explain the slow/long and not agonizing WDs. But in my experience OC IV'd half-life is nothing like 4 hours. It is way, way less. - How do I make paragraphs?! Even BBcode
does nothing..? Also, the protein binding of both pharmaceuticals are similar magnitude so it does not explain my personal experience (MS can easily keep me going 8 hours, from zero tolerance way longer; OC only few hours and 4-6 is pushing it already).
 
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To clarify, I do know a bit about pharmacokinetics and pharmacology in general; so I do understand protein binding mostly affects the "rush" aspect of substances. It is now almost 100 hours since the last Oxycodone and I feel almost normal. What might be going on?
 
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