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  • BDD Moderators: Keif’ Richards

Morphine IR

twotoomany

Bluelighter
Joined
Jan 24, 2013
Messages
736
So I have access to some 15mg morphine ir's. I usually need about 22.5 mg of oxy in the nose hole to feel pretty good. I've looked at the conversion chart. It states oral morphine is equivalent to oral hydrocodone. I can not for the life if me find info on bioavailability via plugging or insufflation. Anyone know those numbers off hand?

I've also read that, anectdotally, chelated magnesium can up the bioavailability for the nose hole ROA. Any truth to this? Do I just eat the magnesium before hand or do I have to rail that shit too? I'll probably end up just eating them, but any insight will be greatly appreciated. Thanks.
 
You need about half as much if you plug it instead of take it orally. IV is 100% instead of 30%orally. I'd plug em if you've pooped recently, but if you haven't swallow them so you don't waste it.
 
please don't waste perfectly good morphine IR by eating it. insuflation will use less product and get you higher more efficiently. Also if youre down with plugging it is more efficient than insuff. if I'm not mistaken Insuff is like ~70% plugging is around ~85% don't quote me on those but I remember reading its something like that. and if you are looking to potentiate your opiate experience try diphenhydramine it works pretty good. I would normally use about 50-100mg of DPH. but I don't know anything about magnesium part. I've heard tweakers say it potentiated amphetamines before but once again don't If there's truth behind it or not.
 
Not that high^, wiki states 36-71% rectally, 20-40% orally. Sure its wiki so take ti with a grain of salt, but I know you aren't getting 70% BA snorting. As a matter of fact, there is a chance snorting isn't a good idea with morphine and will work less than oral, but don't quote me on that. All the info is out there anyway, its easier to do a few google searches than ask a question here and wait for answers that are potentially wrong.
 
"Morphine ~32% oral/rectal, insuffulated- 15-20%, Chitosan(a linear polysaccharide that helps absorb drugs better) has been shown to increase nasal bioavailability of morphine from around 10-20% to over 60%, SC-60%, protein binding 30-40%, half-life is 2-3 hours"

This is quoted from a forum dealing specifically with opiates...just as anecdotal as the other info on this thread, but I'll leave it to the OP to decide what to believe.

Oh and I acquired that info by simply typing morphine nasal bioavailability and the first link on a google seach.
 
I've done a google search and I've seen that exact post. I'd like second and third fact based opinions if they are available. I don't have a lot if personal experience with morphine, although I have plenty of opiate experience...
 
I'm not gonna fuck with needles. I've been blessed with a naturally low tolerance. Despite two years of solid abuse, I can still catch a buzz from relatively low doses. I definitely don't wanna push my luck any more in that regard...
 
I agree. That's why I'm looking for legitimate numbers on nasal bioavailability. Even anecdotal evidence if you can personally back it up.
 
Morphine is not a waste when taken orally, necessarily. Oral morphine can evoke an opiate experience just as any other, save for the rush or quicker onset of action with other routes of administration, IF the dose is a good one. I believe oral morphine gets a worse reputation than it ought to because of the fact that many don't care that much for the 'morphine high' over say oxycodone (especially if they are used to other opioids, and just getting into morphine), for example, but what they do appreciate about morphine is the notoriously 'body-heavy' rush when IV'd, as well as a high that resembles that of heroin quite a bit. Morphine is, sometimes, an acquired taste; it has a thick, heavy, sedating, and warm quality to it that many other opioids do not, and it can seem subtler than what it truly is (as is true with all opioids, on the whole) because of how it feels. Oral morphine, for you, could be quite satisfying, especially considering your small tolerance. Just know that it MIGHT be a sort of an acquired taste. Generally, I do figure that oral morphine is equipotent to oral hydrocodone (mg per mg), but that is not to suggest they feel the same; they just are as much opiate, if that makes sense. I would test the waters with the morphine by beginning at 22.5 mg orally, because you don't know how exactly you might tolerate it, enjoy it etc. Morphine is known for being sedating, truly, so I would start with 22.5 mg orally, which might seem like a low dose, but it is a prudent dose for the first few times with respect to your tolerance. In fact, I might even suggest starting at 15 mg orally - even that dose would do quite a bit, even if you don't 'feel' it at first. Oxycodone is markedly euphoric and stimulating without much heavy effect on the body with respect to the opiate family, and so you shouldn't expect the same thing. Don't dismiss the effects of a small dose just because you don't feel that 'zippy'/'heady' oxycodone high the first few times. It bears repeating - it can be an acquired taste.
 
Morphine is so bad orally is because our body already has a whole system in place for breaking down the morphine we already have in our bodies... Yes we make morphine.

We already have a very high capacity for this exact substance in our bodies.

So when we ingest anything too close to being morphine it gets broken down very efficiently by our digestive system.

The main reason why 3-6 esters are so strong is because they are essentially making an extra steps that are highly fat soluble. Allowing the morphine to achieve very high peaks.

This is also the reason it take very high amounts of morphine to get high orally.

I.v. and subcutaneous are the two best ways to administer morphine followed by rectal...
 
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Thanks for the advice guys. I'm gonna start with eating. It seems snorting has less bioavailability than oral. I'm gonna avoid the spike for now. I may give plugging a shot, but I gotta find a way to "clean house" as it were, before I go that route.
 
Thanks for the advice guys. I'm gonna start with eating. It seems snorting has less bioavailability than oral. I'm gonna avoid the spike for now. I may give plugging a shot, but I gotta find a way to "clean house" as it were, before I go that route.
Snorting has a higher BA than oral.
 
OK, Gado. Can you back that up? I insufflated last night. Today I ate one. Much more pronounced effects today. What has been YOUR experience. It's great that you want to lend your input, but it'd be even better if you could give up some details. How did you arrive at this conclusion? Experimentation? Research? How often do you use opiates, and morphine in particular? Gimme some background so I can put some value in your opinion.
 
I say just take them orally, i have heard more morphine users say it is better than snorting them, theirs only certain pills that work stronger through snorting and morphine is not one of them. I have snorted a 30mg once and the only difference was a faster come up rather than waiting but it also wore off faster, but didn't notice it to be any stronger.

Morphine can still be strong orally at the right dose even though it has a low bioavailibility orally/insufflation which is why most people prefer oxy's over them. IV morphine is not something i would recommend to anyone since the world of IV is on a different level, but i've had it IV through the hospital and liked it way more than oxy's, but even orally despite its low bioavailbility it still is one of my favorite opiates. But that's also because i don't have a massive opiate tolerance.
 
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