Stimulants Modafinil And Dextroamphetemine

[adhd1921]

Hey this is my first post although I have been lurking bluelight for a while.

I haven't been able to find anything about modafinil for ADD let alone when combined with traditional ADD meds.

I am already prescribed dex however from what I've heard modafinil is much smoother and can be used just to give a light wakefullness. It also seems like its pretty darn easy to get online (<snip> don't list sources) because its only a schedule IV drug.

I was also thinking of taking it so that I have an alternative to my current meds so I can lose a bit of tolerance. I'm currently taking some generic Namenda (Memantine), which is a NDMA antagonist like DXM, that I got online in order to combat tolerance.

Is modafinil cross tolerant with amphetamines?
How fast does tolerance build with modafinil?
Would an NDMA antognist also prevent tolerance with modafinil?

Thanks

 

[Mr Blonde]

1) Not sure, but since dopamine antagonists that reduce the stimulant effects of amphetamine do not have such a dramatic effect on modafinil, I imagine there would not be a complete cross-tolerance. Maybe some level of cross-tolerance though.

2) Again not sure, but a google search for user experiences led me to believe that for most users it has a 'favorable tolerance profile', i.e. tolerance does not build up too quickly.

3) No idea on this one, but try it out anyway.

 

[xxl]

I took only 100mg three times a week for a few months. All the same, my tolerance built up quickly.

 

[adhd1921]

I took only 100mg three times a week for a few months. All the same, my tolerance built up quickly.

So modafilin isn't a very good long term choice, right?

 

[xxl]

So modafilin isn't a very good long term choice, right?

Difficult to say. I build up tolerance quickly to most drugs, that may be because my liver is in top condition. An efficient liver is a good thing but it also means drugs get degraded quickly.

Still, don't expect Modafinil to be different in terms of tolerance just because it is reported to "work differently" compared to amps. Tolerance is a kind of immune system directed to chemical (rather than microbial) entities.

If you want to stay awake and feel slightly speedy, Modafinil is worth a try. Then by the time you've built up a strong tolerance new molecules may be on the market. Expect some side-effects like short-term memory loss and absent-mindedness. Take Modafinil to sit an exam but don't study on Modafinil. I suspect these caveats apply to amps as well.

I don't know about ADD proper. With all due respect, I regard ADD as the medical profession's (and big pharma's) excuse to prescribe stims to children.

 

[iameatingjam]

I've never tried modafinil but from what I hear the feeling is completely different. It doesn't have any sort of high or 'tweeked out' feeling. Apparently it just feels like being more awake in the natural sense. (from what I've heard)

I don't know if this would help with ADD

but I really have no idea what I'm talking about

 

[adhd1921]

Difficult to say. I build up tolerance quickly to most drugs, that may be because my liver is in top condition. An efficient liver is a good thing but it also means drugs get degraded quickly.

Still, don't expect Modafinil to be different in terms of tolerance just because it is reported to "work differently" compared to amps. Tolerance is a kind of immune system directed to chemical (rather than microbial) entities.

If you want to stay awake and feel slightly speedy, Modafinil is worth a try. Then by the time you've built up a strong tolerance new molecules may be on the market. Expect some side-effects like short-term memory loss and absent-mindedness. Take Modafinil to sit an exam but don't study on Modafinil. I suspect these caveats apply to amps as well.

I don't know about ADD proper. With all due respect, I regard ADD as the medical profession's (and big pharma's) excuse to prescribe stims to children.

Well I agree with you to some extent on that last point.

I think ADD meds are over prescribed and that a lot of people are labeled as ADD simply because their parents can't deal with their kids. However, there is a lot of people with bona fide ADD who cannot focus on anything for the life of them and have a very low attention span (me).

Some of the biggest pharmaceutical companies like GSK were founded on amphetamine and governments literally gave out dexedrine to their soldiers like candy during WWII.

 

[xxl]

Some of the biggest pharmaceutical companies like GSK were founded on amphetamine and governments literally gave out dexedrine to their soldiers like candy during WWII.

Yeah, it has been written that the battle of Britain was won by amphetamines. In a more recent past, I read that the Iraqi soldiers during the 1st Irak war kept awake swallowing Captagon. Now the US army has been experimenting with Modafinil. What's the use of having a war-on-drugs if wars per se are fought on drugs?

Note that no army would distribute alcohol to its troops. So much for alcohol being a better drug than illicit ones.

 

[adhd1921]

Yeah, it has been written that the battle of Britain was won by amphetamines. In a more recent past, I read that the Iraqi soldiers during the 1st Irak war kept awake swallowing Captagon. Now the US army has been experimenting with Modafinil. What's the use of having a war-on-drugs if wars per se are fought on drugs?

Note that no army would distribute alcohol to its troops. So much for alcohol being a better drug than illicit ones.

I guess drugs are bad unless of course they can get our soldiers to push themselves more. Don't ever underestimate the hypocrisy of the US Gov't.

The main reason amphetamine caused an explosion in the US Phara industry is because before WWII US Pharma was actually much more behind Europe when it came to pharmaceutical research. However, the Germans owned a variety of patents on pharmaceuticals including amphetamine.

Once WWI was over the Allies usurped all of Germany's patents. Since the US was the only country that whose economy was stable and unaffected by the war the US took over European Pharmaceutical production and used all of the Axis' patents as a springboard for slight variations in those medications so that they could churn out new patents.

Thus GSK made dexedrine which is not much more than a pill form of amphetamine.