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  • BDD Moderators: Keif’ Richards

Mixing alcohol, Nyquil, Tylenol PM, ibuprofen, doxylamine and diphenhydramine?

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jkim4007

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Jul 11, 2012
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Other than colossally fucking up my liver, what would these a combo of these drugs do to me?
 
"Colossally fucking up my liver" is probably enough reason not to do something, no? Why are you taking this combo, if you don't mind me asking?

Acetaminophen in Tylenol can be very damaging to the liver and can cause liver failure and death in overdose. The max recommended daily amount is 3-4g in 24 hrs or 1-2g in one dose (guidelines vary) - any more and you are risking serious harm. What else does Tylenol PM contain? A sedating antihistamine? Drinking alcohol while ingesting acetaminophen can increase the chances of doing some damage as well, it's not a good idea.

Ibuprofen isn't heavy on the liver like acetaminophen but it can cause internal bleeding from your gut after overdose or repeated use, so again it is best to stick to the recommended dose, don't take it daily if you can help it, and be alert for abdominal pain / indigestion / bleeding. Alcohol can also increase this risk as it can irritate the stomach and promote bleeding.

Diphenhydramine and doxylamine are 1st generation antihistamines. They are sedating, and combining them with alcohol may make you pass out or could be pretty unpleasant. In high dose they cause delirium which can be truly horrendous and is not at all recreational for the vast majority of people. I would not take two different 1st gen antihistamines and I wouldn't exceed the recommended dose.

Nyquil also contains doxylamine, right? And DXM? You really want to choose one out of diphenhydramine, doxylamine, Nyquil (containing doxylamine) and Tylenol PM (if that also contains a sedating antihistamine).
 
^ all of this, plus the potential of choking on your own vomit and not waking up if you've had a lot of alcohol. This is really reckless and will not be any fun at all, why would u wanna do it? There is no recreation to be had from this, it will mess you up.
 
Absolutely nothing good would come out of this combination.

And dude, you've got one liver. I would take "Colossally fucking up your liver" very seriously.
 
In my opinion, there is absolutely NO value in this combination unless you want to sleep or die or maybe both. Having a messed up liver is extremely painful, and whatever feelings you would get from the above combo wold in no way be worth the storm of shit you would have to wade through after....
 
Take out the tylenol pm and advil at least... This combo is so stupid. Complete waste of a high plus liver damage. Don't do it
 
Well this isn't really for recreational purposes, my goal is to go to sleep and not wake up

was just wondering if that would do the trick or if I'd wake up with a fucked liver or something
 
Well,certainly not going to help you kill yourself, but my guess is that you would wake up with a fucked up liver...not a fun thing to have....why are you considering such drastic action? How old are you? What is going on? Would it help to talk about it a little bit?
 
Please call a suicide help hotline, you can google one in your area. This forum isn't for helping figuring out lethal drug combinations
 
Bluelight is a resource to help keep people healthy, not to advise people on how to kill themselves. I would advice you to talk to someone about your intentions, your therapist, doctor, suicide hotline, etc., or make a thread in The Dark Side, they're very supportive.

And that particular combo sounds like it would cause an extremely painful, slow, and unpleasant death, as in multiple organ failure and brain damage, and there is of course a good risk of it not actually killing you and leaving you maimed.

As I mentioned BDD isn't the place to deal with such cases, but I urge you to check out TDS. Closing thread.
 
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