Mildly novel tryptamine with a dithiazinane tail (DiTT)

[Allylbenzene]

It's reminiscent of DiPT.
The precursor is called Thialdine, it's an OTC perfumery chemical with GRAS status.

Thialdine = 2,4,6-trimethyl-1,3,5-dithiazinane

So perhaps ... DiThiazinyl Tryptamine (DiTT)
SMILES: CC1SC(C)N(CCC2C=NC3=C2C=CC=C3)C(C)S1

The question is... are any of the metabolites toxic and does it risk having unusual effects like the pyr-T's from TiHKAL... anyone care to see how it overlays DiPT & pyr-T?

How will CYP, MAO and SSAO behave?
Tryptamine is an SSAO substrate:

Like monoamine oxidase (MAO), SSAO can deaminate short-chain primary amines, but is insensitive to MAO inhibitors.

— https://doi.org/10.1351/pac200173091393

 

[tuppingtoncity]

This is an interesting one - I have no clue about the potential toxicity of metabolites or its various enzymatic activity, but like you said I would definitely be a little cautious of any N-cylic tryptamines. Perhaps it's nothing like N-pyr tryptamine and co., but wouldn't surprise me if it were to have rather high affinity for 1a and thus some pretty unfavorable effects.

 

[Allylbenzene]

...wouldn't surprise me if it were to have rather high affinity for 1a and thus some pretty unfavorable effects.

It might even be an antagonist which isn't ideal.