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RCs methylone and MAOI?

homeydontplaythat

Bluelighter
Joined
Dec 7, 2009
Messages
1,218
Location
LOS ANGELES
tis very bad to mix the two, correct?

one would have to wait 2 weeks in order to be safe if they were to try methylone, right?

we are talking about one that is one a transdermal patch of selegiline. any info is appreciated. thanks/
 
Yeah, methylone and an MAOI would be quite dangerous. You don't want to mix any serotonin releaser or reuptake inhibitor with an MAOI or you have a very real risk of serotonin syndrome, let alone hypertension.
 
More than likely.

http://wiki.bluelight.ru/index.php/Selegiline

Keep in mind that methylone is not MDMA too. On its own, it tends to cause more stimulation (both CNS and mental) than MDMA usually does. Cathinones are closely related to ephedrine and some of them actually have ephedrine metabolites and MAOIs are the number one no-no for ephedrine.

That extra oxygen added on to MDMA that makes methylone actually changes the chemical pretty significantly.
 
And one would have to wait how long until using methylone after stopping selegiline?

Just like I told you before, selegiline is an irreversible MAO inhibitor so it takes up to 14 days before the enzyme gets replaced..

Any drug that isn't compatible with MAO inhibitors shouldn't be taken within 14 days of stopping selegiline.
 
im reading all these reports of people taking harmaline with methylone and even selegiline with mdma. further, people taking meth with maois. what gives?
 
Allright, while it is possible to mix the two, it is not only idiotic but downright stupid and you run the risk of placing yourself in a body bag. It is far too unpredictable to be mixing MAOIs with any monoaminergic drug. Have others done it before? Yes. Have they lived? Some yes, some no, more often than not they wind up in the ER escaping death by a bees dick. You typically find a lot of reports wondering if MAOI+meth/mdma are ok to take together, but you never find a lot of trip reports saying they did it and died... because your cant post a trip report when your dead.

If you are asking because you have taken a MAOI and want to roll, wait at least 14 days as mentioned after the last dose.

I'm not going be irresonspible and tell you to do it, I am telling you to not do it, forget the idea completely. It is out of the question. I am not joking at all.

You say you have read reports of mixing MAOI+Monoaminergic drugs... read this:

http://www.bluelight.ru/vb/threads/50212-MDMA-MAOI-experienced-Straight-to-the-ER

Following this I got a full blown panic disorder and became suicidal. To this day I have severe depression. I don’t think what I did was smart and I am not proud of it. I am not proud of the fact that I went home after all that had happened and took more drugs. It goes to show the importance of harm reduction. If I had known then what I know now it never would have happened.

Somebody just close this thread, please.
 
i still have more questions. sorry if you want to close this thread. here are the questions:

i have read that MAOI A inhibits the breakdown of serotonin and B inhibits dopamine. would not serotonin syndrome occur from MAOI A inhibition?

could MAOI B cause hypertensive crisis from the dopamine?

lastly, what if one used VERY small amounts of methylone.....would the effects be enhanced or would crisis occur?

please direct me someonewhere if these questions are not appropriate for this thread. thanks.
 
i just found a very interesting thread on reddit talking about the PROs of taking selegiline with mdma. now im totally freaking confused. this guy absolutely advocates using the combination. i wonder if the same applies to methylone. check this out:

http://www.reddit.com/r/DrugNerds/comments/1eau4s/selegiline_to_prevent_mdma_neurotoxicity/

PLEASE DO NOT CLOSE THIS THREAD. i have very serious questions about all this. please do move it to another section if you deem it neccessary. thanks.
 
Both excess serotonin and dopamine will induce a hypertensive crisis/serotonin syndrome if enough is present so doesn't matter what you use... think of PMA, a potent serotonin releaser and MAO-A I in one and MAO-B I say selegiline with methamp.

While technically yes a MAOI can prevent neurotoxicity obviously by preventing dopamine oxidising, it is too risky to get the right dose - the results will be very unpredictable and there is a strong chance you will wind up in the ER or a body bag. Neurotoxicity will be your last concern when your dead anyway. Although the trip report I posted of a MAOI+MDMA the bloke winded up with severe depression/axniety... so there is some neurotoxicity still with reduced oxidative stress potential.

I am telling you not too do this, it's out of the question. I can see you are still interested in trying this as you said thanks for the replies on stopping you from rolling on a MAOI and then obviously went and looked for it more, so the only serious question here is are you that stupid?
 
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Just to make I cleAr I have no intention on using any drugs now that I'm on selegiline.

And will FBI stop poking me asking for RCA sites and where I get drugs. I don't use drugs and the dude asked where I got stuff not where he could.
 
homeydontplaythat, please report the PM so that it can be dealt with by staff.

Great choice on not taking drugs with the selegiline by the way!
 
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