Methotrexate

[BongFish]

Hey thought this would be a question for you guys who know about drug metabolism and stuff.


i've been prescribed 7.5mg methotrexate for my psoriasis, i know its a big no no to drink on this because it will damage my liver, what other drugs should be avoided? I know opiates are ok but I'd really like to be able to take acid/other trips and uppers... what is safe?

Many thanks

 

[BongFish]

are gbl and benzos ok?

 

[Amberthefrog]

I would imagine benzos and acid are fine and gbl probably isn't fine.

 

[Black]

i'd second benzos being ok.

hope you won't have to take methotrexate for long, as it's pretty nasty stuff.

 

[fastandbulbous]

Methotrexate is indeed nasty stuff, causes faults in DNA replication (like the inclusion of uracil into the reproiduced strand). Isn't corticosteroid treatment enough for your psoriasuis - it's all mine needs to beat it into submission

 

[BongFish]

no my psoriasis is very severe, flares up occasional. uv-b treatment works but im im only in bangkok for a month so need it to work really quickly apparently this will help.

any idea is k will be ok to take with it im a big k head... its new years and i want to get off my face! if lsd is ok i presume brdfly is ok too


this is low dose short term treatment, 4 weeks max

 

[BongFish]

hmm k is also metabolized by the liver (hepatic??) so i guess this is a no no too.

 

[RhythmSpring]

Hey, I was on anywhere from 7.5 mg to 20mg of methotrexate for a period of 4 months. During that time I took DMT, pot, and DXMwith no adverse effects.

Fastandbulbous- Methotrexate is nasty, but corticosteroids are just as bad... they screw with your appetite, your mood, and adrenals. Also a terrible drug to use repeatedly.

To the OP- Please consider diet as an option to treat the psoriasis. Like eating raw/vegan and removing any foods that may trigger flare-ups. There is a lot of strong anecdotal evidence for the effectiveness of this method.