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Methamphetamine

contraindications

I. possible drug interactions:

- Sympathomimetics eg: MAOIs (isocarboxazid, linezolid, methylene blue, moclobemide,
phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine, chlorgyline, nialamide, pargyline,
befloxatone, brofaromine, moclobemide)
If taken within 2 weeks before, during, and after treatment with this medication,
in some cases a serious and possibly life threatening drug interaction may occur.
Very high blood pressure can occour. DO NOT COMBINE ANY MAOI WITH METHAMPHETAMINE!!

- Antidepressants (venlafaxine)
Can cause dangerous fluctuations in blood pressure and possible serotonin syndrome.

- Tricyclic antidepressants (amitriptyline, amoxapine, clomipramine, doxepin, imipramine, desipramine,
nortriptyline, protriptyline, trimipramine)
Taking methamphetime with tricyclics can change the way the brain reacts to methamphetamine,
possibly causing more side effects.

- SSRIs (fluoxetine, citalopram, fluvoxamine, paroxetine, sertraline)
Serotonin reuptake inhibitors may potentiate the pharmacologic response to sympathomimetic agents.

- NARIs/Noradrenaline Reuptake Inhibitors (mianserin)
Stimulant effects felt by methamphetamine are almost completely blocked by NARIs.

- Insulin
If taken with methamphetamine, insulin can increase your risk of low blood sugar
(hypoglycemia) because you may eat less while taking methamphetamine (it is an appetite
suppressant).

- Medications for high blood pressure (guanethidine)
Since psychotstimulants can increase blood pressure, they may counteract the effectiveness
of antihypertensives

- Beta blockers (atenolol)

- Medications that affect the acid level of the urine (sodium bicarbonate, acetazolamide)
Alkalinization of the urine can decrease the renal elimination of methamphetamines. Methamphetamine
effects may be prolonged, and the risk of toxicity may be increased.


- Other stimulant medications (e.g., methylphenidate, lisdexamfetamine)
Combining other stimulants with methamphetamine may decrease the effects of methamphetamine.

- Phenothiazines (chlorpromazine, thioridazine, fluphenazine, perphenazine, promethazine,
trifluoperazine)
If taken with methamphetamine, this may decrease the effectiveness of methamphetamine.

- Cough & Cold products (dextromethorpan)
Mixing cold medicines with methamphetamine may cause blood pressure to become
dangerously high or lead to irregular heart rythyms

- Isoniazid (INH)


- Ioflupane eg: dopamine transporter bin
Drugs that bind to the dopamine transporter with high affinity may interfere with the
image obtained using ioflupane I-123, which also binds to the dopamine transporter.

- SNRIs (venlafaxine)
Possibly causes seizures when combined with methamphetamine.


- Serotonergics (MDMA, St. Johns Wort, tramadol, pethidine, triptans)
These drugs have the potential to produce symptoms of serotonin toxicity

- Antipsychotics (colazapine)
These drugs antagonize the effects of dopamine at D2 receptor. Using methamphetamine
with any of these drugs can greatly reduce the efficacy of each drug. May also induce
a meth-related psychosis or psychotic symptoms, or antipsychotic-induced acute dystonias.


II. Pre-existing Conditions that should not be mixed with Methamphetamine

- Allergy to methamphetamine hydrochloride, Desoxyn, or any inactive component in the drug
- Heart conditions including heart disease, atherosclerosis, congestive heart failure, recent heart
attack, certain irregular heart rhythyms (arrhythmias)
- Have moderate to severe hypertension (high blood pressure)
- Severe agitation
- Overactive thyroid (hyperthyroidism)
- Glaucoma
- Have used a monoamine oxidase inhibitor (MAOI) within fourteen days
- Tourette's Syndrome (methamphetamine can exacerbate tics)
- Diabetes
- Pregnant or could be pregnant, or breastfeeding (methamphetamine is passed through breast milk and may effect an unborn baby resulting in low birth
weight)





I am so sorry it took me so long, I was having trouble "working" on my vacation :) Thanks for being patient with me. This is kind of a rough draft, there's more things I will be adding, but I just wanted to get this to you so you had something. Any questions or comments or things I can fix/improve, please let me know! Also, in the very very near future, I plan to attack the ROA section.
 
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Thank you for this! I'm going to format it (in Wiki'd format, that is) and enter. Much love, thank you!

Before I'd posted the Wiki, I wrote up something brief regarding ROA:
Vaya from Meth Wiki said:
Methamphetamine is most frequently insufflated (snorted), vaporized or injected intravenously.
The hydrochloride salt of methamphetamine readily melts and vaporizes without combusting, thus making this route of administration (ROA) not only simple, but efficient. Many users, however, prefer to inject methamphetamine. The user typically experiences a "rush" following injection that is experientially more significant than intravenous amphetamine due to methamphetamine's additional methyl group which allows the drug to cross the blood-brain barrier more thoroughly.

Other viable ROA for methamphetamine include buccal, oral (swallowed), sublingual and rectal (known as "plugging"). Buccal and sublingual administration are generally discouraged due to the extent that methamphetamine irritates the body's mucous membranes. Similarly, even short-term insufflation of methamphetamine may result in profound nasal tissue irritation and bleeding, with long-term insufflation causing potentially irreversible damage to the septum (that which divides your left from your right nostril).
Click to expand...

Delete or add anything you wish, however!

Also, do you have any sources for the above information I could toss into the document?

Thank you so much!!

~ vaya
 
I couldn't help contributing :D Found some handy harm reduction stuff here: http://www.meth.org.au/index.php?id=30
Amount
Try not to use more than two times in a week, and no more than a small amount each time. Have regular or set non-using days each week. The risk of becoming dependent on meth is high for regular users, injectors and smokers of ice.

Injecting
Injecting meth is risky, but if you do choose to inject, make sure you use safer injecting techniques. There's lots of on-line information about safer injecting, but if you're looking for a place to start, try the AIVL site: www.aivl.org.au.

Water
Drink plenty of water - keep a water bottle handy so you can take frequent sips even if you don't feel thirsty. Don't let yourself become dehydrated.

Coming down
Plan a time to come down if you’ve been bingeing or using regularly so you can eat, drink, rest and sleep undisturbed for a few days. Stock the fridge with good food so you don’t have to go out; take the phone off the hook; turn off your mobile; make sure you don't have to go to work or do anything important; avoid making important decisions until you feel better.

Diet
Eat a balanced diet. You can still eat a little even if you don't feel hungry. Weigh yourself regularly to make sure you're not losing too much weight.

Try milk, high protein drinks, shakes, or fruit smoothies if you really can’t eat very much.

Rest
Get enough rest. Going more than two nights without sleep is stressful on the body so plan rest periods too. Even marathon runners plan regular rest breaks. Extended meth binges lasting for 3 or more days can cause visual/auditory disturbances, paranoia and delusions due to lack of sleep. Can also attract the 'shadow people', perceived beings that can cause a lot of distress. Know your limits.

Teeth
Brush and floss regularly, and chew sugar free gum to take some pressure off tooth enamel. Dental health can suffer because meth tends to dry up saliva which helps to fights bacteria. Probably a good idea to check with the dentist every now and then if you're a chronic user.

Plan
Plan for the week ahead and make sure you don’t use (or be in the middle of coming down) just before an important event or commitment. Planning helps to keep life a little more on track.

Mental health
Call on friends or family who don’t use meth if you feel scared, paranoid or panicky. Even though it's sometimes hard to ask for help (some people feel embarrassed or even ashamed), support people can often help you calm down. Don’t hesitate to call for specialist help if you need it.

Take a total break from using meth if you hear, feel, or see things that aren’t there, or start to have strange or scary thoughts. Sometimes people can experience psychosisMental health disorder that can include hearing or seeing things (hallucinations), false beliefs (delusions), extreme suspiciousness (paranoia), and seemingly irrational behaviour. and if this happens to you, get some professional help (e.g. GP, local emergency department, local mental health service).

Lifestyle
Stop and think. Consider if you're doing things that you wouldn’t normally do to get meth. Sometimes people don’t realise that their life has gotten out of control, and your own moral compass is a good indicator.

Overdose
Call an ambulance on 000 immediately if you or a friend overdoses on meth – ambulance officers don’t routinely call police in the event of an overdose, and untreated meth overdose is life threatening.

And just in general... Know what you're dealing with. Meth is a highly addictive drug that will completely take over your life if you allow it. Different people have different patterns of use and self control, you gotta be able to recognise the warning signs and be strong enough to take a break if you know you're taking things too far. Also, be very careful who you associate with in the meth scene. Some people keep their morals, others let the drug change them. Some people didn't have any morals to begin with. This is the hard drug market. Prepare to meet some very unpleasant individuals who will fuck you over at the first chance they get. Use your good judgment and common sense.

I added my 2 bobs worth every now and then, feel free to elaborate or pitch in what you feel like. Sorry I took most of it word fo word, needa shower and sleep shortly. I'll check back in if I think of anything else or find something worth chucking in.
 
I Totally Agree With You Both After All My Years Experience Too. Could you A Person Off Huge Wisdom Possibly Give Me Some Advice Please
 
Youll need to ask a specific, and appropriate, question of this forum before we can help you. Sorry, but I can neither help you synthesize, nor purify, street drugs here. Hence, ive unapproved your first post.

~ Vaya
 
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Just chuckin' in my 10c worth; street slang most commonly used in Sydney AUS is shabs, from the Filipino Syabu / Japanese Shabu, whereas in Perth AUS,meth is usually called simply kuta (etymology of this is unclear but it appears to have been borrowed from Kuta in Bali, Indonesia, Australia's most frequented overseas holiday destination and one of the first bazaars for cheap, high quality crystalline meth when it rocketed into popularity in the '90s. Also spelled koota, coots or referred to as "the koots". This etymology would appear to suggest a strong, if not INTRINSIC link between surfing culture and meth. Similar sociological observations could be made about Honolulu.

Also, a lot of people here used to call crystal meth simply "rock", but this has fallen out of favor and it is sometimes referred to as shunt or shards.

Thanks for an excellent thread!
 
^very interesting sociological extrapolations, gearjammer... what inspired you to make the connections between slang and the subcultures that likely spawned them, alongside connecting these hypotheses between multiple separated populations?

Very interesting, indeed...
 
Meth is not one drug. its.either crystal or powder and hugredifference in the 2. and that's what ppl fail to see. meth has so many varieties . more than any drug. and each is.to be used different and each acts different . so knowledge on small things will allow you to be some what safe doing it. because i dnt fear of a.od.on meth because u can check quality first and uaually if is junk junk u can tell. good cut is hard to see but can be used rather than the crap junkies rip u pff with. simple breaking of crystals or taste of item is enough to bbe.on right path if.i can't test then i won't touch .
 
Knowledge of pure is least Important. gain knowledge on cut methods and how to test or atleattt take a good.guess. cut it what scares.me. not the actual shards. i.won't.touch powder form . if gna risk using atleast make the.risk smaller and dnt let ppl tell u what u get. but look. cause od's r mainly because took junk and still.used. or thought was.bunk and did a.huge shot. but.meth.in pure uncut crystals won't just.drop u dead.smoking pr.snortinng. and iv u know what.to.do.if not u gamble on a strangers drug with ur life. learn not what it chemically is in it. but what is added and used as cut is the important part. real pure u won't find as a.user.because to many young ppl just take and use regardless.if.looks black. Instead of waiting for good and forcing the bad to.stop
but u buy annything a.dood says is good and use it.blindly
weed u smell and.look at. and same with.pills.u read.imprints. so look first . And refuse to buy if can't chek.it out first . duh. knowing how its made don't effect u. but knowing what.its cut with and knowing diffence between the types. p2p, any . phosphorus and so on. andd easy to know by scent s and if ur refused.to check it out then odds are its junk. cause good stuff sells itself . junk needs hustle
 
It was kinda hard to read your post but i think i got the gist of it and i tend to agree. Its what they cut it with thats a problem. Thats what is harming people and causing overdoses.

I met this guy in rehab that was a pretty hardcore meth user. He had been around awhile and knew his shit when it came to meth. Really smart guy, just lost and hanign with the wrong crowd. He would tell me that you literally cant overdose from meth if its clean. He said that his buddy and him would go out to the desert and cook shit up and just mix these huge thick shots together and slam for days.

He said you get just blasted but your not gonna die. Although i just dont see how its not possible to overdoses speeding your heart up like that.
 
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