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Methamphetamine Discussion Thread 3.0

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ebola? said:
Honestly, these questions are in general quite difficult to answer, as we will be for the most part trying to infer from animal experiments involving a very high dosages given a small number of times over a brief period to humans taking comparatively low dosages at higher rates of frequency over long periods. However, there are some notable general trends:

Neurotoxicity: methamphetmaine might be the most neurotoxic of typical classical stimulants. Compared with amphetamine, it induces toxicity (largely through oxidative stress) at lower dosages (certainly having measurable effects when taken in dosages over 20 mg). While it is not entirely clear why this is, it seems that part of what's going on is methamphetamine's higher lipophilicity allows it to more easily diffuse into the presynaptic cell directly, wherein it is more likely to affect the cell's functioning and to be metabolized to oxidative species. So at equi-intoxicating doses, amphetamine will be much safer, and NDRIs will essentially be absent of neurotoxicity. Additionally, meth's affinity for SERT and propensity to release large amounts of dopamine confer the type of serotonergic neurotoxicity that we see with MDMA and other entactogens, albeit milder...well, milder until one binges (as is common with meth). In behaviorally relevant terms, it is really difficult to establish a certain "safe" level. Given that the serotonin system is strongly affected, I would try to adopt once monthly or more infrequent dosing if the doses are high (especially to the point that there is dosing following a night of lost sleep), perhaps a bit more frequent dosing with lower dosages. I can't really see dosing more than once a week being prudent in any sense. One thing that has come out more clearly in the epidemiological data is that regular dosing of either meth or other amps significantly increases Parkinson's risk, due to dopaminergic toxicity localized to the striatum.

As for other organs, meth places significant train on the kidneys, and opulent hydration is key. Luckily, meth doesn't place particularly much train on the liver (beyond general metabolic increase and the other lifestyle correlates that come with regular use). As for cardiotoxicity...well...honestly, I wouldn't really use any classical stimulant with any regularity past age 40. The strain gets more and more apparent as one goes on. The cumulative toxicity seen with regular usage is pretty closely analogous to the damage conferred by a tobacco habit. . .

Hope this helps (sorry it was so vague...)

ebola
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Thanks for this answer!!
I have a much better idea now.
 
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Is cocaine neurotoxic at all?
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It seems only insofar as cerebral vasoconstriction increases likelihood of stroke and induces localized hypoxia (however, cocaine's auxiliary mechanism, as a sodium channel inhibitor, tends to induce cardiotoxicity that exacerbates this). Now, I am defining neurotoxicity pretty strictly, as permanent changes to neurophysiology that induce undesirable behavioral consequences (or would induce such if more severe). The temporary changes in function of dopaminergic signalling that come with cocaine addiction are highly undesirable and severely impairing, but they will abate in months to years.

ebola
 
G'day guys! Just a quick question fuck knows if this is the right place for it.
So last night about 7pm I had a good few decent bulbs and have been up since. I just took 6mg of Diazepam because I thought I'd try to hit the hay but as it so happens I've changed my mind (surprise) and want to kick on with a few more today I'm wondering will their being any horrible effects of cardiac arrest ect lol If I jump staright back on and start pumping it?

Cheers ?
 
canberracrack said:
fuck im fiending a shot/pipe something chronic. bodies full of aches and pains and I'm fucking fanstatsing about a shot or a puff. at least they got me on valium cos they know of my huge habit. they say there gonna taper me down very slowly and carefully
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So I just recently joined these forums about and hour ago and it has been an interesting read to say the least... Canberracrack I honestly feel like your making up the majority of shit you post, "googed up" in other words, but for some reason I'm wrong and all that far fetched shit is true you need to take a long hard look in the mirror and wake up to yourself mate.
 
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I take Adderall IR Rx of course. I notice alot of similarities in the two, adds and meth... But my Rx adds help me concentrate so i can actually function without my mind racing. This is my first time posting i guess im a rookie so if i do or say anything wrong please help me. My question to Meth users is, I wondered if anyone has tried suboxone for the crash off of meth or better yet are there any people here Rx'd to Subs as I am and do they help with crashing from the getty up add gives you? If anyone could help me move this to another thread if needed please do so like i said i am brand new!
 
So I just recently joined these forums about and hour ago and it has been an interesting read to say the least... Canberracrack I honestly feel like your making up the majority of shit you post, "googed up" in other words, but for some reason I'm wrong and all that far fetched shit is true you need to take a long hard look in the mirror and wake up to yourself mate
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In 15 odd years on this site, this is one of the more sensible, insightful, direct and ultimately reassuring Greenlighter posts. DeadKelly, welcome to Bluelight. I am not sure saying, "I hope you enjoy a stay as long as mine" is necessarily the best advice one can give in the interests of harm reduction, but I hope you hang around and go onto be a valuable contributor to this invaluable site.
 
^ Yes me thinks our mutual friend dath not beat about anybodies bush, and or small shrubbery. Solid post indeed.
 
Shz said:
How do I smoke the stem of my meth pipe???
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No expert here, but it's not too hard. You don't want to smoke it from the stem, you want to melt and puddle it back to the bulb.
Finger over the end of it, hold it at a 45 or steeper angle with the bulb at the bottom and heat it from the top, near your finger. Be gentle, you don't want it clouding like mad. When it melts, gravity does its thing and just follow it down to the bulb. Might take a few goes, don't want the stem getting too hot. Also, don't bother after just a few points, let it build up in the stem until you can actually get a fair bit flowing, it's much easier.

I've heard of alcohol washing stems and then evaperating that off on foil. Sounds like a shit load of work for not much result. Unless the pipe sees grams go through it between washes.
 
You will have to have a sufficient enough of a build up in the stem for it to melt into a puddle and reforming making its way back down to the bowl otherwise it doesn't work. If you have only put a gram or so through your pipe and you decide to burn down your stem you just hold your lighter at the bottom end of the stem (the closest end connected to the bowl) and you work your way and follow through towards your face up the stem, remembering to twirl it around your fingers spinning it around. Spinning it around can be a hard task as you get closer to your face because the lighter will burn your mouth and fingers. You might not get much if you have only had a gram run through your pipe but yeah that's how i smoke up the stem when there is a minimal amount been through the pipe. If you have shit loads gone through your pipe then stick to method in the post just above mine :)

Peace
 
did yous miss me >??? hahah looks like yous all read my posts and got warded off the meth??!! Or just been scattered for two weeks? hahahaha

im in the psychiatric wing of hospital in canberra. on a diazepam taper. didn't have a phone charger for a while haha. plus I've been really trying to get a sort of health b ack..walking, playing ball, hiding behind the fucking bushes too smoke ciggies i scab (its smoke free in here and cunts gotta sneak em in when they come back from leave) rehab doesnt take u till your clean, its no dice while your still on a taper. So thats off the cards atm. I'm also on olanzapine for psychotic symptoms of my wig out. I was on a two week order, which got renewed yesterday. sucks donkey balls but i dont think I'm gonna see the last of this place for a while. mate I've made in here reckons ill be in for a good 3 months :/ fuck can u do ay. its doing me good in some ways i guess

i haven't had any meth since my skitz out~!! i haven't been granted leave yet from here. should be getting some asap though. leave is u get to fuck outta here for 2 hours. if u arent back in two hours a warrant gets sent out hahahaha. theres flats just basically across the road (fucking lol) my mate can score from, he's getting leave tomorrow most likely so can smuggle some back in for me...said he should be able to get a pipe back in too so that will be fun...

feel way better from the meth break..shit my brain was/is fried. withdrawals have been a total cunt. body aches and pains and feeling flat/depressed but light exercise helps and it really aint as bad as i thought/some say. i suppose my valium dosage (60mg currently, coming down weekly) is helping.

i think ill be fine to have a pipe tomorrow. gonna go this bloke just halves in a point so i won't even be too tweaked just have a pick me up, but mate seems trustworthy, promises he won't shaft me. says its always on the dot and is primo shit. i kinda wanna shot but he doesnt shoot so he's just gonna bring a pipe back and we will share a point...says depending on who's there he might get chucked an extra .5 or so so it should be aight,.
 
^ Best of luck mate, try and focus more on your recovery than scoring meth, if they catch you with that shit you can bet your situation will only go downhill further. It is good that you seem to realise that you are there for a reason and are benefiting in some way.
 
thanks mate ^^^^


it is however...pipe time baby!! mate just got back with it and said we got about 1.5 or so so were gonna sneak to his room make sure the coast is clear and pipe on lads!! Pipes in the mental ward bahahahaha

on another note does anyone know how it will interact with olanzapine??
 
Good to hear that cnberracrack is getting at least a taste of treatment so in future if he relapses(many do, some don't) he will know whether detox is for him. I don't think detox is bad at all, its not even close to the level of shelter you get from the outside world, its obviously not something anyone would be jumping over the moon bout but the idea of detox is to make it easier for you and if they aren't making it easier theyre not doing their job! I enjoy NA, and home detoxes if possible(benzos need to be plentiful as somehow I had a gigantic tolerance taken effect in the last 3+ years yet im not dependent and never have been in many years of use and abuse, sorry only used long enough to form a physical dependence once and no matter how long I have a break for I still need silly doses. That's was Xanax mostly though, I use a lot more clonazepam now which I find is better in ever way to Xanax.

Tonight is my fourth night awake and I actually feel almost as though its my first. Either its very strong, very clean crystal, the food and vitamins ive been gorging on is keeping me nourished or that im just getting lucky. I had 0.1g IV a few hours ago, 0.1g IV yesterday, nothing the day before and 2 points IV before that. Is it possible that this is 4-MAR? I usually start getting psychosis symtoms on day 2 and I am pretty damn normal. Im also not insanely anxious which is almost a given if I have more than one shot(I usually Iv a point and ride that out till the next day and that's it, though I have bee a daily user too) Im sure Xanax would be helping me stay calm but this stuff is different. It lasts sooo long, is sooo clean, I don't get the usual meth taste after a shot and its helping me feel more normal(as in it gives me the motivation, social confidence, sexual drive/confidence that methadone robs me of) but still, its not the norm for me to be so fried from so very little

4-MAR?.
 
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the_ketaman said:
Good to hear that cnberracrack is getting at least a taste of treatment so in future if he relapses(many do, some don't) he will know whether detox is for him. I don't think detox is bad at all, its not even close to the level of shelter you get from the outside world, its obviously not something anyone would be jumping over the moon bout but the idea of detox is to make it easier for you and if they aren't making it easier theyre not doing their job! I enjoy NA, and home detoxes if possible(benzos need to be plentiful as somehow I had a gigantic tolerance taken effect in the last 3+ years yet im not dependent and never have been in many years of use and abuse, sorry only used long enough to form a physical dependence once and no matter how long I have a break for I still need silly doses. That's was Xanax mostly though, I use a lot more clonazepam now which I find is better in ever way to Xanax.

Tonight is my fourth night awake and I actually feel almost as though its my first. Either its very strong, very clean crystal, the food and vitamins ive been gorging on is keeping me nourished or that im just getting lucky. I had 0.1g IV a few hours ago, 0.1g IV yesterday, nothing the day before and 2 points IV before that. Is it possible that this is 4-MAR? I usually start getting psychosis symtoms on day 2 and I am pretty damn normal. Im also not insanely anxious which is almost a given if I have more than one shot(I usually Iv a point and ride that out till the next day and that's it, though I have bee a daily user too) Im sure Xanax would be helping me stay calm but this stuff is different. It lasts sooo long, is sooo clean, I don't get the usual meth taste after a shot and its helping me feel more normal(as in it gives me the motivation, social confidence, sexual drive/confidence that methadone robs me of) but still, its not the norm for me to be so fried from so very little

4-MAR?.
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Only way to tell is to Reagent test it. If it shows up signs of meth then it's meth. If not then it.could be anything.
As for old mate, pretty sure he already has relapsed before he left rehab. He did say he was getting on in there. I'd say he got caught to so he is probably getting held down
 
^^^ well maybe because of the intense dopamine rush genius!!!! meth is fucking incredible!!!!


Ive been going and getting toasted nearly everyday in this place!! I got my own leave now and Ive got a new connect up at the apartments. Go up have a big shot of about .50- 1.0 then come back peaking into the ward and just smoke ciggies and talk shit all day!!

The rushes Ive been getting are so much better and cleaner. this stuff is primo as all fuck!! I crashed for a bit last night and went for fat shot today at about 1pm of a point..been rushing hard as FUCK like hard as FUCK.. god damn I'm still beaming like a cunt andf it was so hard to hide how toasted i was in front of all the staff lmao i was off my absolute dick
 
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