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Opioids Methadone Mega Thread and FAQ

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Taking methadone on a full stomach doesn't really reduce the efficacy, but it may take longer to kick in. Holding it your mouth won't help, neither will snorting etc....

Also, anyone who says methadone comes on in 15 minutes might not have much experience. Regardless of the thousands of times i have taken methadone (literally, in the thousands), it has never come on in 15 minutes (unless IVed, of course). It used to take at least 50 minutes to begin feeling the effects. This is simple the nature of the drug....
 
^^^If I'm sick when I take it,I definitely feel better within 20 minutes or so.but not the full effects.After 1-2 hours I become extremely hungry with a nice little pleasant euphoria.
 
Yeh, I've only had "limited" experience.....nine years. Stating that someone else's experience indicates inexperience, because your own experience is different is pointless.

The responses simply show how variable perceptions are among users.
 
Seeing as I didn't get a response to my earlier response, I took 5mg Methadone at 4:40pm yesterday, with another 5mg Methadone at 8:40pm. There's a possibility I will be consuming 30-60mg extended releases morphine, and perhaps 10-20mg of oxycodone in the form of 10/325's, and perhaps some adderall in the form of 15mg instance release tablets later this evening approx 6-8pm.
I also have the option to consume more methadone, but due to it's half life was thinking that the previously mentioned option would be safer?
Safety wise is there any reason this would be a problem? I also have no intention of drinking this evening as I feel that would be an un-needed risk. I have a relatively low opiate tolerance I believe.
For example Halloween over the course of a night I consumed 30mg xr morphine, 45mg oxycodone, and 30 mg adderal xr, with 3-5 drinks and had a good buzz but did not feel like I pushed it to far. On weekdays I consume approx 100mg tramadol and 5-10mg hydrocodone with higher dosages such as the one on Halloween for weekends. If anyone could chime in with some input before later this evening it'd be greatly appreciated.
I have read through tons of threads on all these various pharmaceuticals and feel I'm at least somewhat knowledgeable but would like some more input from experience members, as yesterday was my first experience with methadone. I didn't feel overwhelmed by any means, I ended up nodding and passing out about 6 hours after the 2nd dose, and still in a good mood today.
I am aware of the long half life, and tend to have a fast metabolism, and a lower body weight approx 120-125lbs.
I'm tempted to post this as a separate thread as I haven't had much luck in general getting answers in mega-threads but I'll give it another go, as I hate to circumvent the rules for my own benefit ;)
Thanks in advance for any input anyone may have.
 
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When I first started using opiates methadone was given to me. I started with 5mg (then, I'm a smaller girl) and that did 'something' to me. I was great at 10mg. I wouldn't do anymore than that-not yet.
 
I've mixed methadone with any number of other opiates without negative consequences. Once methadone is active in your system in sufficient amounts it can block the effects of other opiates, but given your scenario this doesn't seem to be the case.

As in any of these threads, the info you're getting is experience and opinion, not medical advice. Be careful.
 
It can certainly come on within that first half hour if you're on MMT. I definitely felt it pretty damn fast when I was on. I don't have much "recreational" experience with methadone, just a maintenance stint between oxycodone and buprenorphine, so I'm thinking maybe it takes longer to affect someone who does not have methadone built up in their system already...
 
In my opinion , methadone shouldn't be used by those without an opiate tolerance-or even a weak tolerance at that. I've taken 10mg and had that be enough to make my heart feel like jumping out of my chest. It's caused panic attacks, etc. I've had to leave work early because I was freaking the hell out. Start with 5 then 10 mg if you've never had it before and don't take many opiates. This drug IS a bit dangerous to those naive regarding the effects/correct dosage. If you're informed, it can be alright.
 
I am on 170mg through a Methadone clinic, and I wish I never started. Yes, it got me 0off the opiates, but now I have to get off the methadone. To top it off, I stopped taking Suboxone to take the Methadone. Bad mistake, considering now I have to show up at the clinic everyday to get dosed, where with the Suboxone, I got a prescription every month, which was allot easier.

If you are using Meth on the street to detox, good luck, it's just as addictive as dope. I know people who got stuck on 10mg and couldn't get off...
 
Don't hear of too many folks switching from suboxone to methadone.....what's up with that? Don't get me wrong, I'm a firm believer in the benefits of methadone. The problem is access. Once in the clinic system, you must follow their rules, which are ever-changing. The Federal guidelines aren't too bad, its the State rules that caused me problems. Every time the administration changes, so may the rules.

It was an absolute circus when I was on MMT. Jumping through ridiculous hoops was par for the course. It has dawned on me that the MMT system can serve as a snapshot of the kind of nonsense we might all be forced to live with should the abomination called "health care reform" become law. Whenever government inserts itself between patients and their physician, trouble ensues.
 
It can certainly come on within that first half hour if you're on MMT. I definitely felt it pretty damn fast when I was on. I don't have much "recreational" experience with methadone, just a maintenance stint between oxycodone and buprenorphine, so I'm thinking maybe it takes longer to affect someone who does not have methadone built up in their system already...
I am currently on MMT for the third time in my life, this time since 8/20/09. When I take my dose, it takes about an hour for me to start to feel it. Keep in mind that it is not getting me "high", more of a "glow" type of a feel, and only for the first couple of hours after dosing.
 
^It obviously affected me a bit differently than you. I only felt the glow for the first two or three hours as well, but it started really soon after taking it (it was a syrup, btw)...

I think it's strange in how it affected me in a few respects, actually. The switch from 30mg methadone to ~2mg bupe insuffulated actually was more than equivalent; it gave me stronger effects. From what I read, this is not typical (I remember a post by negrogesic a week or so ago about him taking sub for the first time and comparing 4mg insuffulated and 2mg sublingual to like 15mg methadone...)
 
I've never insulfated sub but i would like to sometime. The two times I have been on bupe programs it was in an inpatient setting where they would watch you take your pills and check your mouth n stuff :-(
 
^I actually wasn't in a bupe program either, I just got on because the $11/ day for MMT was ridiculous compared to the cheap price of 8mg subs divided into pieces.
 
Being on methadone now at 70mg/day (started the program a few weeks ago), the dose still isn't holding me until the next morning. Usually I start to feel kinda crappy around 9-11pm.

I get a bit uncomfortable and sweaty with minor aches and pains. Have some trouble sleeping and tend to wake up in the night a few times. Still have nightmares.

Is it a possibility that I'm a fast metaboliser? Should I ask if I need to dose twice a day? Or should I keep titrating my dose of methadone up to see if a higher dose will hold me off longer? Tomorrow I should go up to 80mg/day so I'll see if it helps but I'm not too sure it will.
 
Catching a nod on methadone?

Ok so basically I am taking 70mg of methadone/day. I know methadone doesnt "block" opiates in the same fashion Bupe/Sub does but once you reach a certain level of dosage with methadone it does saturate the receptors so that additional opiates have little-no effect.

I took 80mg of OC tonight after work (dosed my m-done this morning at 7am) and didn't really feel much of anything. If I were to take some oxy in the morning before I took my methadone - would I have a better chance of feeling it? I know I can always take the mdone after the oxy but if I take it first i'm concerned ill just be wasting it as I really didn't feel much of anything and that was a good 12+ hours after dosing my methadone.

Any comments/suggestions welcome!

Thank you.
 
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