TheBookBurner
Bluelighter
- Joined
- Mar 14, 2023
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ChatGPT says:
The metabolism and chemical breakdown of methamphetamine and related substances are well-documented in pharmacological literature:
The metabolism and chemical breakdown of methamphetamine and related substances are well-documented in pharmacological literature:
- Methamphetamine Metabolism: Methamphetamine primarily metabolizes into amphetamine in the body. The primary metabolic pathways include oxidative deamination, aromatic hydroxylation, and N-demethylation, resulting mainly in amphetamine as a metabolite. However, methamphetamine does not metabolize into ephedrine or pseudoephedrine; rather, these are chemically distinct substances and are not byproducts of methamphetamine metabolism. (Source: National Institute on Drug Abuse (NIDA), "Methamphetamine", and the U.S. Drug Enforcement Administration (DEA), "Drugs of Abuse").
- Sources of Ephedrine and Pseudoephedrine: Ephedrine and pseudoephedrine are common in over-the-counter medications, particularly those for colds and allergies. They can also be used as precursor chemicals in the illegal manufacture of methamphetamine, which sometimes leads to contamination in street methamphetamine products. (Source: U.S. Drug Enforcement Administration (DEA), "Methamphetamine and Amphetamines" and World Health Organization (WHO), "Ephedrine and Pseudoephedrine").
- Analysis of Illicit Methamphetamine Contaminants: Studies on illicit methamphetamine have found that street samples can contain various cutting agents or contaminants, including ephedrine or pseudoephedrine, depending on the manufacturing process. This can happen if the methamphetamine is synthesized from precursors that contain these substances or if they are used as additives. (Source: Journal of Analytical Toxicology, “Analysis of Methamphetamine and Related Compounds in Illicit Samples”).