Meth+MDMA, bad combo?

[GFunk02]

I got some green omega rolls that tested positive for meth and mdma (comfirmed this using the 3 tests of ez test extreme), they felt great, mostly mdma-ish.

I am wondering how bad this combo is for the brain, because meth releases dopamine, and dopamine is what gets into serotonin receptors when the serotonin is running low due to being pumped out by the mdma, from what I understand.

Is taking a paxil when the high is almost over going to help this? Lots of vitamin C+E? Or should I just get rid of these pills if I am concerned about the health of my brain?

I plan on taking them with lsd or miprocin (i took them with miprocin the other nite, what a great experience), I wonder if this combo will reduce/increase neurotoxicity. I know most of the replies will be theory and not fact, just looking for an intelligent reply from Blizor or anyone else that has understanding of this kind of neuropharmacology.

Peace

 

[Rcin]

What I would be concerned about is the overheating factor. MDMA makes your body temp rise a great deal, but in conjuction with a strong straight up stimulant like meth it could make it very hard to keep your body temp normal. This would be the biggest issue to me, because most of the studies show that drugs that produce any brain toxicity are increased in their destructive properties once hyperthermia becomes an issue.
...I forget where I read it but I remember seeing a study where they administered monkey's with MDMA and found nearly no brain damage, then heated the monkey's up to a few degrees over normal and found a lot of damage to the dopamine and seratonin systems in the brain.

I highly doubt you'd need to go to the ER if you take this combo, but it would cause some damage no doubt. Meth is just a very hard drug on your brain period, but mixing it with MDMA would make it more damaging. Sorry I can't back this up with more refrences and facts, as I don't have everything I've read about these types of issues at my fingertips. But I'm fairly sure I'm giving you accurate info, I guess we'll find out once BliZor gets his hands on this thread.

 

[BilZ0r]

Your view on MDMA-mediated neurotoxicity is a bit 1998. The whole dopamine into the serotonin neurons is a bit unlikely... it's something I'm begining to doubt happens even a little bit now. But we'll see... either way... of course taking meth and MDMA is going to be worse for you than taking either drug by itself.

Forget about the paxil... there's no point in taking serious drugs that could fuck you up even more when there is no point, and there really is not point, unless you take the paxil at like t+3 hours, and then it's going to stop your roll.

If you want to be safe, just make sure you don't dance too hard and get really hot, and even better, take fat soluble anti-oxidants, like vitamin E, A and alpha-lipoic acid.