Meth/Amphetamine use while on AntiDep (SNRI)

[Stato]

Hi All,

I have recently been started on anti depressants, specifically I was on 30mg cymbalta daily for a month. This has now been doubled to a 60mg dose.

I am aquiring some Methamphetamine and have heard bad things about combining amphetamines whilst on anti depressants.

Should I stop taking my Cymbalta for a couple of days before the meth, or will this be OK to continue my regular dose of 60mg (keep in mind I have only taken 2x 60mg so far... so only just been put on the stronger dose)

Also, what would you all suggest for the best ROA, smoking, snorting, eating it in a capsule? I have 0.1g and will likely be taking this in one dose.

Cheers,

 

[Christ!]

Wouldn't reccomend taking meth if you're on an anti-depressant. Some people find they feel pretty low for a week or so afterwards.

Not sure if you can just stop taking Cymbalta without having side effects, or messing up your treatment.

IME SNRI don't totally mess up the effects of meth...not like MDMA with anti-d's for example. You should be ok to just take the gear without going off the cymbalta, you might feel like the meth is just missing a certain 'something' but I don't think it'd totally ruin it.

 

[hunter1]

^ As Christ said, from a harm minimization point, taking recreational drugs whilst on anti depressants is counter intuitive but i can completely understand why you would want to do so. Your depressed, flat, the meds are not giving you your desired effects ect.

I have not taken Meth deliberately although know many who have and many who have been on ssri/snri's.

If your going to do it I would not stop taking the cymbalta. Keep taking it as you normally would.

As Christ said, you will most likely not feel the full strength of the high. I wouldn't go chasing rainbows with dosage either to counter effect the cybalta.
Basically, decide your dosage beforehand and don't keep taking more to try and fill the gap.

Good luck with Cymbalta. I tried it for 2 months and it was clearly not the med for me. Currently on Prestiq which so far has been somewhat promising so far. Whether or not it's just (side) Effexor without the side effects or just a patent extender it's too early to tell but if you find Cymbalta isn't for you I would suggest giving prestiq a go under the supervision of a medical professional.

In the end, antidepressants will not work properly whilst your still doing drugs. You have to be really ready to give the gear away to give the meds a true chance.

My 2 cents

 

[Divine Moments]

Antidepressants and Recreational Drugs FAQ

 

[Mr Blonde]

^ Good link.

You may notice a qualitative difference in the 'feel' of the methamphetamine whilst on the SNRI, but over-all it shouldn't make too much of a difference. The important thing though, is that using drugs like these whilst suffering from a depressive/anxiety disorder can worsen your condition our and will not help you to recover in the long run. You should definitely consider a break from drugs whilst you are treating your depression/anxiety.

 

[kaiba]

I know someone who is prescribed by a psychiatrist, Cymbalta (forgot the dose) and Dexamphetamine (45 mg a day).

Antidepressants plus adderall/ritalin/dex seems to be not uncommon in discussion forums.

 

[WarChild]

Hey

Yeah anti depressents don't mess with meth that much. Only slightly. As for adminstration - if you've only got 1 point then smoke it for sure. If it is ice/high grade smoking a point will do you nicely. However i try and take my doses orally as i have found it gives a more long lasting euphoria over smoking.


Cheers

WC

 

[tyrael]

As others have said, if possible, try to cease all methamphet usage while on (any sort of) AD!

You most definitely will feel different effects if you do decide to take methamphet while on an SNRI. Even with SSRI's there is a slight (or 'not so slight' ) interaction. Maybe see my post in Advanced DD (if you're that way inclined) here.

To break it down simply, your methamphetamine is a sympathomimic drug so it's gonna be dopaminergic and (nor)adrenergic, your AD (anti-depressants) are SNRI's - Serotonin–norepinephrine reuptake inhibitor. See the commonality here?

So basically (and I have found this personally being on Paroxetine myself) you will notice reduced efficacy (that is, how well it works) of the meth!

If you must dose, try to be generally sensible about it. Try to - limit the frequency, limit the quantity, eat healthy, etc. General good living!

Conclusion is that, with that quantity you've mentioned, you should be fine.

As Mr. Blonde said (and listen to him, he's a smart man! ), regardless of any pharmacological interactions, the fact that you're in a point in your life where you require (medical) help, exacerbating the situation with (any kind of) mind-altering substance isn't such a good idea.

Good luck though (and welcome to BL! )! And let us know how it all goes!