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Mescaline Tolerance

C

cooh

Greenlighter
Joined
Jul 8, 2010
Messages
13
Been searching around on this subject and have read mixed reviews. On Thursday night I took mescaline in the form of San Pedro/Peruvian Torch cacti (they were mixed together) at a dosage of 20gs. I would estimate this to be the same potency as a 250-300mg Mescaline HCl trip. I have the same amount of cactus (20gs) and would like to trip again, about 48 hours later. Would my mescaline trip be greatly diminished? Also, if I were to take the 20gs about how long into the trip would I be able to redose, with say 5gs of cactus powder, considering tolerance (in an attempt to boost the trip, not extend it). Thanks in advance!

(if this should be in BDD, sorry for fucking up again!)
 
No problem posting it here....

well I created a plot for this sort of thing a while ago based on all classic psychedelics:
psilocin/mushrooms, LSD and mescaline/cacti.

If you are saying it is 48 hours later then you can read in the graph in the thread I linked to that in average and subjective terms it would take 220% of your normal dose to get the effect you want. So that is 2.2 times larger because of tolerance.
That one is based on mushrooms and LSD however, mescaline or cacti are less often consumed and actually mescaline gets metabolized differently or so I have heard. There may be a deviation from the number I gave.

This is not exact science but it's the best answer I got :)
 
Yeah, I recall seeing that graph a while ago. Reason I ask is because a friend of mine dosed probably around 20gs of this cactus one night. And then the next day took a dose of about 35 and tripped pretty hard. So it seems mescaline may be a bit different from LSD/Psyclobin?
 
Well the thing with mescaline seems to me that first off it's a pretty large dose compared to everything else (around 250-300 mg) which very much occupies MAO enzymes, and this apparently is a self-reinforcing effect. Since it simply cannot be broken down it remains effective.

But we must remember other than that it is serotonergic like the rest and can be expected to get a respond as such.
 
As a phenethylamine (as opposed to a tryptamine) you might well find that the tolerance builds and drops slowly like other phenethylamines, whereas tryptamines are the opposite.
 
I don't have anything to say about tolerance, but I will comment on dosage.

Mescaline HCl is more or less precise. If the extraction has been done properly you will get just what you expect. This is not true of dried cactus, which is what I presume you are referring to when you mention '20 grams.'

The other thing is that I would not expect a 20 gram dried cactus trip to be as strong as 250-300 mg of HCL. I've done 340mgs and it was a very solid medium,.i.e. no question at all you are tripping for 12 hours, a substantial peak, etc. 20 grams, depending on the plant(s) might be quite a bit lighter.
 
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