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Melatonin and MDMA

dezz

Bluelighter
Joined
Oct 15, 2011
Messages
1,662
Hey you guys,
So I've been taking melatonin because I have problems falling asleep. It's doing the job fairly well. Anyways I'm rolling this saturday and I would like to know if there is any risk in taking it after to fall asleep?
 
As far as I know there is no immediate risk. Melatonin can cause depression in some people but it sounds like that isn't the case for you?
 
I took melatonin for weeks on end during a VERY sensitive period of time.
There was substantial insomnia during the first several months of recovery.

Considering how sensitive my serotonin system was this last year, I think I would know if there are any negative side-effects to melatonin.
I never noticed a single negative effect from the drug.
Some nights it really helped me sleep, but often it did not.
It seemed to have the greatest effect when taken on a regular basis - at least 2-3 days in a row.

Of course, lowering light exposure at night goes hand in hand.
Considering you are going to be on a rather strong stimulant and possibly exposed to lots of light, you will probably find melatonin to be lacking in effect.

But there is no risk, in my utterly cautious opinion.
And it may even offer a small amount of neuroprotection.
Valerian is a great companion to melatonin, by the way.
I think this would offer a greater effectiveness than melatonin alone.

Benedryl is NOT recommended.
I took a high dose (100mg) at 48 hrs. past my first mini-binge on MDMA.
I would swear on my own grave (and nearly did) that DPH + MDMA = Serotonin Syndrome

My best guess is that the metabolites of MDMA that were still in my system were allowed to wreak MAJOR havoc due to CYP2D6 enzyme inhibition from the high dose of DPH. This may not qualify as 'typical' SS, but SS is a poorly understood condition in the first place.

A 25mg dose of DPH following a SINGLE dose of MDMA would be very unlikely to cause such an adverse event.
But I still highly recommend against its use, esp. to 'regular' consumers of MDMA.

The shorter version of this post would have said - no problem with melatonin, but I'd add valerian to it. Don't take DPH.
 
Hey, I know melatonin is subtle but I REALLY notice the difference. Some nights I'll be wide awake and when I decide to drop some melatonin, I'm ready for bed in an hour or two.
I like valerian aswell, but it only worked for me the first two times, after that I didn't feel anything, it just stopped working. :P
 
It gave me terrifying sleep paralysis when I was using it to get to sleep while coming off a rediculous long term weed habit. HORRIFYING sleep paralysis. I was literally afraid to go to bed because I knew what was coming, but melatonin was the only thing that would keep me from tossing and turning all night and not getting a wink of sleep. I had been stoned morning til night for years. Based on my experience with it, I would stay the fuck away from melatonin apart from the odd night of coming off hard drugs, in which it would help. It's really best to limit messing with your neurochemistry though.
 
melatonin is naturally produced in the brain. There is no harm in taking it. To think you'll fall asleep from it, though, is kind of a stretch. I have found it doesn't knock me out unless it's the afternoon the next day and I haven't slept yet.
 
Some nights it does help me sleep.

If I am not tired, it does NOTHING.
If I am moderately tired - it really does work.

Valerian is the shit, if you take several doses.
It is pretty safe to do this with.
One or two pills will increase dream activity for me, while four will make me feel very pleasant and almost drunk for hours - if I stay awake.

Kava is nice too, but not safe for continued use.
It is associated with liver and skin problems, and it feels kinda yucky to me.
I can tell the liver enzymes don't like it somedays.

But valerian is awesome.
End post.
 
Alright, so I got some valerian, they are pills containing 3 ingredients: 210 MG Valerian, 210 MG Passion flower and 180 MG Melissae Folium (whatever that is..)
So how many mg's of valerian would you need to induce sleep?
 
Passion flower and melissae are fine, but valerian should be higher.
That is a combo pill that gives less valerian to save the manufacturer money.

I buy the Spring Valley brand at Wal-Mart with 133mg of 4:1 extract and 33mg of plain root per pill.
I don't know if the 4:1 extract equates to 532mg?
I seriously doubt it.

But I have to assume it has at least the equivalent of 200-250mg per pill.
Normally ONE is enough to encourage sleep and improve REM sleep, if I'm tired.
If not, i'll take two.

Four is required if I want to stay awake and enjoy the 'drunk' feeling.
After MDMA, I imagine 2 of your pills along with a melatonin would do the fucking job.
 
Ah okay, will do. Your posts have been very helpfull, thankyou :)
 
Works for me

I take melatonin most nights, as I'm naturally a night owl but my I have to get up early for my "real person job."

I also take it after rolling, and it does the trick for me. No side effects, and definitely helps me fall asleep. Plus, it's an incredibly potent antioxidant, so you could be helping your body stave off further damage from the MDMA!

I've heard you're not supposed to take melatonin at the same time as 5-HTP, but I haven't seen it confirmed anywhere so it could be bullshit.
 
Wait what? Melatonin a potent antioxidant? Win-win situation!
 
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