Someone should get on a really big beat and rap about doing a whole bunch of meth. Something like (in rhyme form, obviously) "Now I can have sex and deal drugs for four days at a time!". Just the biggest, most overblown street rap song ever. And then, after a sleepless week of selling crack and blowing people's heads off, they go crazy and have to be temporarily locked in a mental institution, where they suffer a fatal heart attack.
They could call it "We Tweakin'".