Mechanism of action

[i are spectre]

what the heck about other phenidate esters? ritalinic acid is converted already... which im guessing has its own effects... a lot of us eat esters in food...

im thinkin propyl, dipropyl, isopropyl/ethyl, etc phenidate... but im all chem with little knowledge of ligand binding, dimers ,etc, just a college level A&P

but i could see turning that COOH into a whole mess of things... sheesh!

i hope for longer half lives, less side effects, which ive already noticed with the larger ethyl group...

id rather have it than adderall... adderall puts me to sleep... even at 90mg... weird huh. im going to get back to my old doc and talk about it.

my last one ditched out. he left a hand written note on the door of a vacant building. phone line shut off. he's gone, that train has sailed... back 40 of clarksville...

anywho, i was on bupe and ritalin... ethylin doesnt seem like its gunna be too easy to get too soon...

pm if you wnna chat....

 

[Tussmann]

I thought ADD was supposed to keep the "lets state blatantly wrong information as fact with no source" people out.

...

I find that doubtfull, i have to dig up references but i beleive more inhibition needs to take place for therapeutic effects.
"The occupancy of dopamine transporter (DAT) by bupropion and its metabolites in the human brain as measured by positron emission tomography was 6–22% in an independent study[129] and 12–35% according to GlaxoSmithKline researchers.[130] Based on analogy with serotonin reuptake inhibitors, higher than 50% inhibition of DAT would be needed for the dopamine reuptake mechanism to be a major mechanism of the drug's action. By contrast, approximately 65% occupancy or greater of DAT is required to achieve euphoria and reach abuse potential.[131] "
Refs are on wiki but will dig them up when requested, also the ref that




The metabolite does increase da enough but to get that you must be a rodent or have a rodent liver.

Thank you.