Regarding the brains way of coping with complete SERT depletion (sorry Cocha if it seems that I sometimes use the former terms to an extent that they are perceived as different rather than synonyms for Serotonin) throughout all inter-cranial parts and neuralpathways including the very bottom of the brain stem before we hit the first vertebrae, creating normal stainable biosynthesis of SERT post-MDMA administration by the means of neuralplasticity is not a hypothetical situation, it is actual and applicable immediately after MDMA neuraltoxicity.
Looking at a "normal", post-adolencent, just-old-enough to fall into adult-age human pre-drug/trauma brain contains roughly 82,1-, to 110-billion neurons, this number (still argued over pfffft, I think we're ballpark-over it already here) was calculated by -Maxwell et. al. 2001- studying hundreds of FMRI's, PETS, normal X-Rays and advanced MRI's from inception circa 1970 to present and using countless mathematical formulae and synthetic models and many methods of calculation almost always naturally comes up with and leads us to this number that is averaged to the estimation of between 86-, and 110-billion neurons, give or take 11-billion.
Examples of formulae such as 1.) theorems of naturally-occurring, observational-dependent living unit dispersion, 2.) super-imposed and quantity-estimational result of pinpointed positional micro-, and macro-systems' impositions and also more basic biological calculations for estimations and results on organisms and natural area dispersion 3.) taking a sample size ie. 1cm(2) x 1cm(2) and using surface area x sporadic spread x possible occurrence x factor of time etc. etc.
Okay. Now each neurons' dendrites' nerve endings may have the ability to connect with 4,000 to 21,000 other neurons' dendrites' nerve endings through creating and sustaining synapses. These pathways connect relatively distant areas of the brain and the entirety of the nervous system throughout life and these specific connections ultimately makes up your consciousness as memories, experiences etc. Lets look also into the biological arena that is the ability of separately contained biological systems' ability (i.e. organs) for auto-restoratitive, self-repairing abilities and phenomenon, such as the obvious regenerative properties of the liver as one example.
Let us look into the biological arena that is the ability of separately contained biological systems' mono induced-expression for auto-restoratitive, self-repairing abilities and phenomenon with obvious regenerative properties such as those of the liver as one example thereof. Now looking at a “fresh” brain/cluster of neurons. The normally occurring biological and physiological prosess of Neurogenesis starts roughly between weeks 2 and 3 post-conception, pre-foetus, and continues until birth at the rate of 250,000 new neurons per minute.
Neurogenesis is coined as the brain's ability to create new neurons independently. After MDMA-induced neurotoxicity it is not just repairing the damage done through chemically-induced degeneration, oh fucking no, but it has the full capacity the ability to actually grow entirely new and fresh neuron-sites, formations also of completely and entirely new, independently located neuron-clustered areas, all with new cells with new dendrites with new axions and new nerve endings void of defects with perfect bio-synthetical synaptic electro-magnetically induced relay and absorption capabilities never used and ready for immediate training and rewiring-applicable assossioations of 10 to the 10th degree squared ready for data packet handeling via and through its neighbouring neuron-cluster. Most people think this is it. Even orthodox amd new-school academics in the field still insist that we are born with x-amount of neurons for life, full-stop. This limits neurobiology in its entirety and is also an ignorant approach to the most complex accumulation of cells that forms this biological supercomputer that is used and/or abused for your personal pleasure. This ignorance is no longer acceptable in my eyes following a paper and study done at the -SALK Inst. in San Diego et. al 1999- when the neuroscientists there discovered neurogenesis happening in a 72-year-old's brain!
Dude, at 72 you can still take up and master the violin and become a master of it within 5-10 years (or 10,000 hours as Malcolm Gladwell asserted is the average amount of practice/input/involvement/man-hours necessary to master any field of study or any doctrine or any type of any physical activity) As professor of Neurology at Harvard Medical School, Dr. A. Pascual-Leone hypothesized: you only need to do a certain action/think a certain though/experience an event or new environments, and by regular practice/mindfulness/repetition neurogenesis can, does and will occur up until physical bodily death.
This ignorance is no longer acceptable in my eyes. One specific paper published about a study done at the -SALK Inst. in San Diego et. al 1999- when the neuroscientists there discovered neurogenesis happening spontaneously within the frontal and lateral brain tissues in a 72-year-old's brain!!! Dude, at 72 you can still take up and master the violin and come to master it within 5-10 years (or 10,000-hours as Malcolm Gladwell asserted as the average amount of practice/input/involvement/man-hours necessary to master any field of study or any doctrine or any type of any physical activity and master it completely)
As professor of Neurology at Harvard Medical School, Dr. A. Pascual-Leone hypothesized: you only need to do a certain action/think a certain though/experience an event or new environments in a constant manner, and by regular practice/mindfulness/repetition neurogenesis can, does and will occur up until physical bodily death.
Imagine the experience of physical-bodily death, your entire source energy matrix detached from the body, all personal experiences from all previous lifetimes are accessible and are experienced at once, no pain, nothing but pure source energy vibrations, 4-7th dimension existence throughout all time experienced simultaneously and also not so. Just a state of bliss...okay way off the path here let's get back to the point I was making. I think I was concluding the following, I think.......fuck knows where am I again? What day is it today....? Phuza Thursday! In South Africa there is such an overwhelming alcohol abuse situation that spreads country wide haha. Mieliemeel beer Mondays, Tequila Tuesdays, Wacky Wednesdays, Phuza Thursday (ethnic slang for “to drink alcohol profusely”), and then the obvious Hoza Hoza Weenend! Dude fuck Ireland, during the FIFA Football world cup in 2010 I saw first hand how 4 or 5 black ethnis grandfathers above the age of 60-70 drink the Irish spectators under the fucking table they could no longer grasp onto none the less actually sit at. Okay wayyyy off topic, will post as I compose later.