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MDMA Recovery (Stories & Support - 4)

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Propranolol sees use in anxiety/panic/nightmare/PTSD type disorders but I haven't heard about its use in LTCs.

But that's too bad about the Klonopin, I'm sorry :(

And yeah I imagine for a while it's just going to be catching yourself, but that is a triumph. Catching yourself even 5 times a day compared to 0 is great progress. I hope you can keep it up, hang in there.
 
I think I have some information that is worth sharing with you guys.

During my LTC I have being trought the most of the common sympthons that are listed here.

Including Insomnia, palpitations, fast heart beating, brain fog, earworms, sexual dysfunction, tremors, numbness, pricking, blured/grainy vision. I had all of these and others. There are very few researches about what could be possibly causing every one of this sympthons, if they all appeared because of chemichal or neuronal alteration after the ingest or abuse of ecstasy itself, because of stress, anxiety, but they are all produced by our minds, and that means LTC sufferers may have specific alterations of determined neurotransmitters, neuroreceptors, hormones. Knowing that I think any kind of information that could lead to a way of manipulation of this in order to improve the sympthons should beconsidered.

In past 4 days I had an experience with Ritalin, which is a stimulant known by increasing dopamine and noradrenaline levels in brain. Some would say it's effect in higher quantity can be compared to the effect of cocaine which is also a stimulant of dopamine.

I remember that, after my LTC i tried coke once. It was horrible, I think all my sympthons were potencialized. I did used it before LTC and had pretty great highs, but after the LTC it was one of the worst days ever. I just couldn't feel that confidence and good feeling of coke that felt before, i just felt very anxious while everyone around was ok. So I thought that it was too little and snort some more which made things worse, like a comedown just after snorting with simply no good effects. Well after that I stopped using anything and eventually recovered from my LTC.

So after trying ritalin I can say I felt some pretty similar effects to the exact same sympthons I had during LTC like Insomnia, palpitations, fast heart beating, brain fog, earworms, sexual dysfunction, tremors, almost all the sympthons in a pretty similar way. Of course that it was temporary, after the effect of ritalin went away i became normal. But even smoking weed while on ritalin was exactly like smoking whe i was pretty bad. That said i think that in order to reduce this sympthons you would problably need to work with your dopamine levels just as the serotonin. Maybe the anxiety is related to too much dopamine, or maybe if you're running low of serotonin the normal quantity of dopamine will not work normally, maybe you need this both neurotransmittor in a stable level.
 
Abstinent MDMA users have been found to have around 10% more dopamine in one particular area of the brain. It is possible that excess dopamine could be contributing to symptoms. Personally I got a fair amount of relief from my symptoms (insomnia, brain that never shuts off etc) from antipsychotics, which work in part by blocking dopamine.

On another note, it's known in animals that if you stress them, their dopamine levels rise. In other words, dopamine is not always this "happy/euphoria" chemical. Selective dopamine reuptake inhibitors have even found to be dysphoric by some.

With MDMA specifically, all of the dopamine release seen with MDMA has been found to be mediated via serotonin. But it's more than possible that SSRIs, which function very different than MDMA, could have different effects. After all, dopamine reuptake inhibitors vs. dopamine releasing agents have been found to have very different effects on the pattern of dopaminergic cell's firing.
 
When will my ears stop ringing?!!

Not sure about the answer to that but one thing that is true for me is the better I feel the less noticeable that and the accompanying visual snow I have is. Its a lot easier to tolerate it when you feel better mentally. But when it truly goes away I have absolutely no idea.

Thankfully for me visual snow is the one and only "HPPD" symptom I have. Similar to tinnitus, its worse when I am stressed.

To cope with tinnitus I don't really notice it during the day when I am busy and I use a fan at night to drown it out.
 
Anyone tried 2cb post LTC?

My feeling is since its not neurotoxic I should be fine, but might as well ask before I go for it?
 
I would be very careful. Those are some vary potent compounds.

I'd advocate using shrooms or LSD instead... But I'm guessing you live in Canada where the 2C series are still legal.
 
Not even worth thinking about taking it, if it were me.... You could get HPPD that won't go away....
 
Not sure about the answer to that but one thing that is true for me is the better I feel the less noticeable that and the accompanying visual snow I have is. Its a lot easier to tolerate it when you feel better mentally. But when it truly goes away I have absolutely no idea.

Thankfully for me visual snow is the one and only "HPPD" symptom I have. Similar to tinnitus, its worse when I am stressed.

To cope with tinnitus I don't really notice it during the day when I am busy and I use a fan at night to drown it out.

Sounds similar to me.... It's at night that my tinnitus is most noticeable.... Fan does help. Sorry about the snow, I'm glad mine only flares up occasionally.

No floaters for you? What about the tingling face? The left side of my face and forehead continues to tingle....most at night when I start to get tired.

How long have you had the tinnitus?
 
Sounds similar to me.... It's at night that my tinnitus is most noticeable.... Fan does help. Sorry about the snow, I'm glad mine only flares up occasionally.

No floaters for you? What about the tingling face? The left side of my face and forehead continues to tingle....most at night when I start to get tired.

How long have you had the tinnitus?

Tinnitus/vis snow since the beginning (aka since February). Almost been a year but not quite. I think they are both linked for me. Mentally my main problem is depression rather than anxiety but I have both. Idon't have anything concrete to be depressed about other than the mental state of depression itself. IE depressed about being depressed.

No floaters. And certainly no tingling face.

I thought you were the one with HPPD though?
 
I was diagnosed with mild HPPD by doctor Abraham. I have occasional snow, flashes of light, things moving in peripherals, and big black translucent floaters.

My main mental symptom is anxiety and racing thoughts. no DP/DR or bad depression, although I get depressive thoughts occasionally. If this is still going on a year from now though I can guarantee you I'll be depressed. I give you much credit for making it this far though, I'm sure the snow will clear up at some point for you.
 
Thanks to the Sertraline and a shroom trip about 2 days ago I feel perfectly fine again, those people that still feel this emptiness inside should really consider trying SSRI's for a time.
 
Thanks to the Sertraline and a shroom trip about 2 days ago I feel perfectly fine again, those people that still feel this emptiness inside should really consider trying SSRI's for a time.

When you tried an SSRI for the first time. Did you just feel like you didn't stick with it long enough? Or, that it wasn't going to work for you at that time?
 
That's a bit longer story.

I already tried it in the 6th month of my LTC and paradoxically it made my symptoms even worse. This feeling of emptiness got much stronger so I eventually felt nothing anymore.

At this time I also had a car crash, where a other vehicle crashed into our side (nothing happened), and it was so shocking for me that I actually felt nothing at all. I wouldn't even care at all if I would die in this crash, at this time my feeling were actually totally absent.
Because of this I decided to quit after 2 weeks.

About a month later I tried it again for a few days, with the same result. I also drank some alcohol at a party the night I began the treatment and it was the living hell. I couldn't talk with anyone, permanently thought if I would just jump down somewhere and kill myself it would end this misery. 3 days later I actually mentioned a bit of a positive effect, I still was very numb but walking in the forest actually felt like something good again. But eventually because of this negative experience on the first night and those before I quit again after 5 days. Maybe a badly thought out decision.

So now (13th month of LTC) I started to take it again because my depression was really bad and I couldn't force myself to do anything at all, that was about 2,5 weeks ago. At the beginning I felt a bit bad, especially in the morning my brain felt like scrambled, but only for about half an hour. This side effect eventually subsided after the first week, and now I feel normal again. And now there is no numbness anymore, it's quite the contrary, I feel like I gained back the power to feel emotions, take decisions, and so on. And it's not like a permanent euphoric state, it's just normal, like you would expect from a healthy person.

The shroom trip was quite weak because of the SSRI, but it also helped me to find this feeling of normal enjoyment again, just like watching a sunset and feeling the beauty of it.

It was the absence of those feelings, that drove me so crazy and depressed during the LTC and I'm grateful to be able to feel this again.

It really seems that the brain needs a lot of time to recover to a state where medication helps. I didn't wanted to see this fact either at this time, but this is maybe how a LTC works.
So my advice would be, try the SSRI route at least for 1 week. If you feel worse, stop it, if you feel you are getting better, stick to them.

I got enough pills for about one month from now, then I will try to live without them. If it really gets worse again, I will continue to take them, but I will make an update of my state at this time.

P.S.: I also started to take prepared curcuma again (3-5g/day) together with the SSRI's to support the positive long term effects like higher BDNF levels and the reversal of negative effects of stress on the brain. Curcuma alone had no antidepressant effect on me, but on the long term it will surely help.

P.S. 2: (lol)
I tried a combination of microdosing (3 weeks, 0.3g/day) and higher dosages (2g) of Iboga rootbark in the 8th month but still without any notable positive effects. It shocked me a bit because Iboga is named as one of the most powerful natural psychoactive substances and even helped heavy heroine addicts. But it really seems that in a early stage of LTC, and this could be sadly even some months or longer, no medication seems to cause some release. But I'm not familiar with other alternative treatments, and everyone's LTC is different, so this is my way the things went. Try to listen to other people who had success with their treatments and leave no chance open to do something to feel better.
 
That's interesting. I'm thinking if I don't see improvement in my current state, I may go the med route. It's almost impossible to live when it gets bad.

I think that it's tricky because some people get worse for two weeks and then they get better. So how do I know when to stick with it and when to bail?
 
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I think it's possible that an atypical antipsychotic (Zyprexa or Risperidone for example) could help with the the first few weeks of worsening if that is a thing for you, but that seems to be dependent on dosage and stage of the LTC.
 
I think it's possible that an atypical antipsychotic (Zyprexa or Risperidone for example) could help with the the first few weeks of worsening if that is a thing for you, but that seems to be dependent on dosage and stage of the LTC.

One thing I am wondering about though is with a hormonal component couldn't antipsychotics also cause a bad reaction? (Prolactin/Dopamine/Testosterone etc). Like say LTC has already lowered T (which it has for me and I wonder if others have the same) either as a result or a cause then wouldn't taking an antipsychotic potentially really worsen it from impacting the pathway I mentioned above?

The other thing I am wondering about is if hormonal dysregulation at the hypothalamus and pituitary *itself* impacts response to certain psychiatric medicines and whether that component needs to recuperate and then more normal reactions to medicines would happen? Amml alluded to this when saying something about the brain calming down.
 
I wouldn't personally take an anti-psychotic if you have HPPD symptoms......look it up....you'll find Nothing good. They might work (they did for Cotcha)....but they seem like a big risk
 
It is true that there are case reports of Risperidone making some people's "post LSD visual syndrome" worse but I would be open to the idea of LTC sufferers being unique, but mainly for some people that whose HPPD symptoms are most primarily related to sleep deprivation (which was my case).

Sensory gating goes to hell with sleep deprivation and antipsychotics can help with that - personally they also helped with my audio problems.

Of course I recommend caution with all drugs.
 
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It is true that there are case reports of Risperidone making some people's "post LSD visual syndrome" worse but I would be open to the idea of LTC sufferers being unique, but mainly for some people that whose HPPD symptoms are most primarily related to sleep deprivation (which was my case).

Sensory gating goes to hell with sleep deprivation and antipsychotics can help with that - personally they also helped with my audio problems.

Not HPPD related but I was wondering if "uniqueness" overall in terms of meds could be related to what I mentioned above if the endocrine regulation (done by the brain) has been thrown off compared to things like MDD if that hasn't happened. Although I guess even MDD sufferers have endocrine regulation thrown off too? Is it standard in MDD to end up with a subclinical hormonal dysregulation as well? And, if so, how come that isn't addressed more often. Seems like research papers are all over it. Or do you think it will be in the near future? And also whether it plays a role in not responding properly to typical medication trials or having adverse effects. The unpredictability and wide variation basically. Not that its the only thing.

Lots we just don't know.
 
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