He took MDMA 7 times in his life and after that he started Tranylcypromine (Parnate).
7 Months ago he stopped taking Parnate and even many months after stoping Parnate MDMA gives him only very fast hearth beat and anxiety. Like the only neurotransmitter that would work is Norepinephrin and Seratonine and Dopamine seemed not to be active at all.
Today he snorted 50mg-70mg 3CMC and he experienced almost exact same thing.
Did Parnate changed something in his brain that Dopamine/Seratonin releasers don't work anymore?
7 Months ago he stopped taking Parnate and even many months after stoping Parnate MDMA gives him only very fast hearth beat and anxiety. Like the only neurotransmitter that would work is Norepinephrin and Seratonine and Dopamine seemed not to be active at all.
Today he snorted 50mg-70mg 3CMC and he experienced almost exact same thing.
Did Parnate changed something in his brain that Dopamine/Seratonin releasers don't work anymore?