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MDMA + Diphenhydramine?

Plouch

Greenlighter
Joined
Dec 21, 2012
Messages
6
Hello, all.
About 1 month ago, I took some Diphenhydramine to not feel sick(nauseas) during a travel to some place where I planned to roll. I didn't thought of my car medication to have any interactions with Molly.
So I took this 90 Diphenhydramine tab, and maybe 11 hours later, I took some 100-125mg mdma tab. I felt effects that were quite strange, not the usual. I felt euphoria but not as strong as usual. I took some other 100-125mg 1,5 hour later, same state of mind.
Then I finally took another tab, dosed the same, another 1,5 hours later. I took it when the roll ended, so actually I wasn't feeling anything, dumb me ..
Anyway, in addition to theses effects, I felt some strange effects, and this since the first tab. My jaw was quite clenched since the first tab and when I tried to speak, it opened by fits and starts. It was actually the first time I had negative effects with molly.
Another effect is that it was very difficult to pee. Finally, I had some quite little shaking(at the end of my hands mostly) some times.
The come down was quite hard, and I felt quite bad for 1-2 weeks
My friends rolled with the same batch perfectly. I searched here for more information, but except knowing it had some SSRI-like properties (serotonin reuptake inhibition ) I didn't find anything interesting.
Could this be a serotonin syndrom? I always tried to be into harm reduction but I wasn't aware of the effects of the Diphenhydramine .. My last time with molly was 5 weeks before that time
The fact that I felt bad for 2 weeks and that I had stomach problems(I had little stomach problems before but these were way harder) makes me think of an SS , any idea?
 
No, not really HR, this was not tested. I did the tabs my myself, and it looked, smelled, and tasted like MDMA.
I know, this is not a way to know if it really is so no real answer.
 
i am not a doctor, but no, this does not make me think of serotonin toxicity.

Serotonin is actually directly related to digestion and the stomach in general.. 90% of the body's serotonin is in the stomach!


OP you'll be fine though, the two drugs do interact but not dangerously so. Next time avoid the pills before hand and you'll be fine
 
DPH is a vasoconstricter and has deliriant effects.

Its interaction with MDMA may have intensified the stated symptoms.

This is a very good question and I do not doubt that the science of this drug combination goes deeper than a simple explanation.
 
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The box of my medication says " Diphénhydramine 90 mg " so that's a little higher than 25mg lol .
I think you're right, Renz Envy. It may only have intensified the (negative) effects. Somewhere else to look would be that MDMA raise stomach acids, and so can cause theses stomach symptoms..
But, for the more "classical" symptoms that lots of people got, such as jaw clenching and being unable to pee, where can this come from? I never suffered from that while rolling, that's strange.
 
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