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MDMA consumption, while pregnant

We covered this a bit a few months ago:

Originally posted by Invalid Usename

http://www.bluelight.ru/vb/showthread.php?postid=2047627#post2047627

s0nic said:
I doubt there are too many doctors who know very much about the damages MDMA can have on a fetus. It's nothing that has been extensively researched with humans.
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No kidding. (btw, this would be far from being a fetus at this point.)

Reproductive Toxicologists are a rare bird, and many of them are research scientists, not MDs.


I don't know of many studies involving the first trimester. One such study was done at Rush Presbyterian-St. Luke's Medical Center in Chicago last year. Here is a report of the study:
http://www.nih.gov/news/pr/aug2003/nida-29.htm

Before you read the study:
The results of the study are somewhat concerning. But I'd like to point out several things: that rat metabolism is much faster than is a human's. And the exposure schedule in the study (rather unrealistic) is twice per day for 6 days total (and probably at abnormally high dosages of MDMA). That's 6 days out of a 21 day gestation cycle for rats.

Considering the length of gestation for rats compared to humans, this would be like taking a large dose of MDMA, twice per day, for a full trimester. You're friend ONLY took 1/2 pill, and ONLY once.

I would say that she doesn't have anything to worry about. That is such a low dosage, and you are only talking about one incident of exposure. In all honesty, I would think that her having a few alcoholic drinks in that period would be more threatening to her baby, than the MDMA exposure that she has had.

My advise would be to not worry about it. Even the specific cells which MDMA has an affinity for do not exist in the embryo at this stage of development. But if she still feels concerned, then recommend that she discuss this with her OB/GYN. He will be able to recommend if she needs to see a specialist or not.

Good luck, and tell her not to worry. Over 30 million MDMA dosages are taken worldwide in any given weekend. Imagine how many of those dosages are going into pregnant women who are not aware of it yet. This is probably far more common than you'd think. And healthy kids are still being born. ;)

:)



Like I said before, finding a physician who specializes in reproductive toxicology is hard to find. I don't know where you live, but if you are in the states she may want to look up Dr. Lillian Swiersz at the Stanford University Medical Center. Dr. Swiersz is a member of the Reproductive Endocrinology and Infertility Faculty, and she has a background in reproductive toxicology. Chances are she might be able to help pinpoint someone close to you with the right background.

Here's the contact page for their clinic:
http://www.stanfordhospital.com/clinicsmedServices/clinics/reproductive/REIhomePage.html

And here are a list of the physicians working in the Reproductive Endocrinology and Infertility Faculty (including Dr. Lillian Swiersz):
http://www.stanfordhospital.com/clinicsmedServices/clinics/reproductive/REIfaculty.html


I'm not a doctor, and what I am about to say is not medically authorative.

But given the number of exposures she's had, I would suspect that there isn't that much to be concerned about (though I do encourage her to follow up with an evaluation by a specialist).

All of the rat studies that I've read, which show damage, are are performed with a continuous, high dose exposure, over long periods of times. If the same study method were applied to a human, it would equate with constant, high dosage use, for months. A sustained exposure for up to one full trimester, or 3 months.

That's a far cry from 5 medium level exposures, each approximately 8 hours in duration, spread over a 5 month period.

That's not to say that taking MDMA while pregnant isn't a risk, using any recreational drug during presents a certain risk to the child. But I suspect that this is more common an occurrence than is documented, as a lot of females take MDMA, some of them who are pregnant (without knowing it), and result in having healthy offspring.

Anyway, give them a call over at Stanford Medical Center. I'm certain that they'll be able to help you find an OB/GYN in your area with a sufficient background to help out.

Best of luck :)
 
LWA said:
check out:

http://www.erowid.org/ask/ask.cgi?ID=36
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I just read that reference and I don't find it authorative or timely.

MDMA
This seems like one of the worst. There's still raging debate about the effects of MDMA on the brain, but it's difficult to refute that it does make changes to the brain chemistry of humans. This seems like something to avoid with a developing fetus.

...

Asked By : Sy Hall
Answered By : fire
Date : 6 / 27 / 1999
Question ID : 36


It was a reply made by "fire," in 1999 (we were all still chasing after prozacs to post-load with back then), and little was known about MDMA except for the largely rigged research funded by agencies like the NIDA (the best that he had to go on at the time).

What he is basing his response on is simply "gut" feeling, and he even uses the phrase "This seems like" twice in one paragraph. :D

I'm not saying this to belittle fire, far from it. He's was just trying to help someone with the best that was available information wise, at the time. But there's no benefit to that reference other than its common sense, "No recreational drugs during pregnancy."
 
wasnt there a study done on cell cultures that suggests MDMA exposure in developing braincells results in more active seratonin and dopamine systems? i remeber seeing somewhere on this site...
 
therollingstoner said:
"e puts holes in your brain, and your childs too"
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if a doctor ever says anything as ignorant as this to her, they are just trying to scare her because its a falacy.

Some good points have been made already.
She should definately speak honestly to a doctor, and seriously consider whether she wants to continue with the pregnancy. If there is a chance that the baby might be adversely affected by her drug consumption then she should look not only to the impact it will have on her future child, but also what will happen to her own life -
if she is already have dilemnas about whether this is the right time to have a baby, think how much more difficult it will be to support and nuture a baby as well as look after herself in all respects if the child indeed has some emotional problem.

My sympathies to your friend, this must be very difficult for her.
 
I know this thread was started a few weeks ago, but i think it is very important and a lot of people have/will find themselves in this circumstance.

My wife and I took e approx 2 weeks after conceiving our first child, without knowing she was pregnant. When we realised, we felt the feelings of fear/guilt etc that you might expect and i researched the web for everything i could find. i wanted her to tell her obstretician so we could get the latest research but we decided that we would be judged for having taking mdma. This was back in 2002 and there was one major study back then and still one now that i can find. It has been harder to find now on google than it was a few years ago, however, this link provides a summary:

http://www.erowid.org/chemicals/mdm..._lancet_1/1999_mcelhatton_lancet_1_text.shtml

There are a lot of disclaimers in the article and a lot of different circumstances, however, the finding was 66/78 = 85% normal births. it was enough to freak me and my wife out a bit before we had our child. however, read it closely and the risks are very low - the uncertainties are high and regardless, the so called defects are minor.

This is clearly a serious issue, however we have a healthy beautiful baby girl and we know other people who have inadvertently exposed their unborn children to mdma.

one couple we know of had e at leat 5 times in the first 3 months and they also have a healthy baby girl.

obviously no-one should take any un-prescribed drugs once they know they are pregnant, but it is quite common to still be taking drugs before you know.

I think (without being any sort of specialist) that it is more likely to be overheating while on e that may harm a foetus more so than the actual drug itself.
 
MyDietMainlyAmines said:
I think (without being any sort of specialist) that it is more likely to be overheating while on e that may harm a foetus more so than the actual drug itself. [/B]
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First of all I'm glad to hear that your child is healthy. It's good that you took it upon yourself to do as much research as you could. What you found out is probably more than any doctor could have told you.

I think it's more than just overheating that can harm a foetus.. a drug that releases large amounts of neurotransmitters could theoretically be pretty bad for an undeveloped brain. My guess is that MDMA probably has the potential to be more harmful during the later stage of pregnancy, but that's just a guess. I realize that nothing has been proven when it comes to birth defects and MDMA use during pregnancy.
 
Pippin said:
if a doctor ever says anything as ignorant as this to her, they are just trying to scare her because its a falacy.

Some good points have been made already.
She should definately speak honestly to a doctor, and seriously consider whether she wants to continue with the pregnancy. If there is a chance that the baby might be adversely affected by her drug consumption then she should look not only to the impact it will have on her future child, but also what will happen to her own life -
if she is already have dilemnas about whether this is the right time to have a baby, think how much more difficult it will be to support and nuture a baby as well as look after herself in all respects if the child indeed has some emotional problem.

My sympathies to your friend, this must be very difficult for her.
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it's not difficult at all for me thank u very much
 
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