farmacista
Bluelighter
there aren't any studies about mdma's bioavailibity when is taken orally? and when is snorted?
N&PD Moderators: Skorpio
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mdma bioavailibity
farmacista
Bluelighter
there aren't any studies about mdma's bioavailibity when is taken orally? and when is snorted?
pofacedhoe
Bluelight Crew
look up caffeine and mdma absorbtion
farmacista
Bluelighter
mh wasn't useful
farmacista
Bluelighter
i was looking for mdma's bioavailability not interaction
sekio
Bluelight Crew
There aren't, it seems.
Oral BA is variable based on dose. Bigger doses are better absorbed.
Given that a "good oral dose" is considered to be about 120mg, and comparable injected doses anecdotally are about 25-50mg, that means it's probably something like...
oral: 30-60%
nasal/rectal: 60-80%
farmacista
Bluelighter
no, don't think nasal is higher rhan oral...how is it possible?
sekio
Bluelight Crew
Lots of drugs have higher BA via non-oral routes, because orally administerred medications have to be processed by your liver before they make it into your blood, resulting in a loss of drug.
Anecdotally, most people who do nasal/rectal MDMA report they have to use less than they'd use if they did it orally.