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Lysergamides Make your own 1-acetaldehyde LSD at home from LSD, very similar to ALD-52 or the real orange sunshine

tregar

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Make your own 1-acetaldehyde LSD at home from LSD, very similar to ALD-52 or the real orange sunshine

Timestop said:
Quote:


Tregar do you still like to take 1-acetaldehyde LSD via the sherry wine method? I don't have any cactus at the moment to combine it with but I am wanting to give it a go versus normal LSD, how long is the mixture good for if stored?


Good to hear from you my friend Timestop, was just thinking about you! Yes, it's the only way I take LSD, 1-acetaldehyde LSD is no different than ALD-52, same exact effects. Just drop your LSD hits into a shot glass with 1/2 shot of cold sherry wine, put it in fridge and just stir it with a straw every so often around once an hour for 3 hours, the acetaldehyde in the wine will adduct onto the bottom NH group, as aldehydes are easily attracted to NH like a magnet, and bond well under acidic conditions, drink as such. You will love the effects, flowing visuals, no choppy visuals like normal LSD, way more colorful, look up ALD-52 on the net, same exact effects as ALD-52, people preferred ALD-52 over LSD as it was without anxiety, you could take much higher doses with no confusion, more colorful with flowing visuals...Albert Hofman himself invented ALD-52. The "electricity" of LSD is replaced with a more natural feeling. The man-made feeling of LSD vanishes and becomes more nature like.

You can leave the shot glass with wine and LSD hits in fridge and it will keep for weeks, or freeze and it will keep forever, then just defrost an hour before in the fridge, as it's wine it will defrost fast, then drink it. Always keep cold as acetaldehyde boils off around room temp or 70 degree F.

Another thing you must try is then take around 100mg of pure THH or tetrahydroharmine at the same time as you take the 1-acetaldehyde LSD, she (thh) has numerous similarities to mescaline, and the combination of the two is absolutely incredible, it will feel as though you took a dose of mescaline with your LSD, THH + 1-acetaldehyde LSD is the only way I ever take LSD, I've done this for years...it's so bad ass and super cheap combo.

You can find studies for the bonding of the acetaldehyde to the NH group if you go to this link and read the 9th paper on post #1, Tryptophan analogues form adducts by cooperative reaction with aldehydes and alcohols or with aldehydes alone, 1992 Austin.pdf 780.97KB: https://www.shroomery.org/forums/showflat.php/Number/27850299

I've also attached the study here for convenience.

Not only will acetaldehyde bond to the bottom NH on the indole of LSD, but it can bond to the H on the amide of LSA, forming LSH, more than 5 studies all prove this happens, even the 1960 study by Arcamone, all papers in link above.

From post #19: https://mycotopia.net/topic/111610-hpbcd-dmt-sublingually-active-under-tongue/

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Part 15: How to theoretically form 1-acetaldehyde LSD (similar to ALD-52 or 1-acetyl LSD, Orange Sunshine) from LSD hits
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1-acetaldehyde LSD (nearly identical to ALD-52) will theoretically form when you drop hits of LSD into 1 shot of fridge cold just opened sherry wine, stir once an hour for 3 hours, keep in fridge at all times, as acetaldehyde boils off at room temp or 69 degree F, then consume...all explained below:

Sherry wine is high in acetaldehyde (10mg per 30ml or shot glass). This serves as an advantage...why is this important?

Page 8441:

Quote:


Reaction of Indole with Acetaldehyde: A 0.2% solution of indole in equal amounts of water, ethanol, and acetaldehyde formed a product with 60% yield after 1 hour of reaction at ambient temperature. Omitting the ethanol (50% acetaldehyde in water mixture) had no effect.

Decreasing the concentration of acetaldehyde to 0.1% increased the reaction rate and percent yield of product.



See pic of the researcher's indole + acetaldehyde adduct product formed before (page 8439) and after (page 8441).

The researchers achieved a new product with or without the use of ethanol, it made no difference, you only need water acidified to around ph=4 and around a 0.1% acetaldehyde solution, and around a 3 hour soak time for 100% conversion.

Sherry wine fits the bill perfectly with it's high acetaldehyde content, and low ph, which is already at ph=4, just like the study calls for. The researchers stated "the lower the PH, the faster the reaction (indole adduct formation at the NH group)." It contains the perfect amount of acetaldehyde as well, in an alcoholic medium no less.

It is quite possible that 1-acetaldehyde LSH and 1-acetaldehyde penniclavine produce stronger visual trips with zero anxiety. This has been my experience with the seed solution and also my experience when converting 3 x 100ug blotters of LSD to 1-acetaldehyde LSD (have done this over 10 times already spaced at least two weeks apart during the past two years), also confirmed recently by Namaste at the Shroomery to work for him as well, now his preferred method of consuming LSD as well.

Once you know your morning glory seeds are potent, you could also throw in a blotter or more of LSD into the sherry wine/morning glory seed solution soaking in the fridge for 3 hours, not only will this convert the LSD to the more visual, colorful and anxiety free 1-acetaldehyde LSD but it can result in a trip way beyond normal LSD. Example below:

Dragonrider:

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I have also experimented with morning glory seeds a lot. A couple of times the seeds came very close to LSD. I have combined morning glory seeds with other psychedelics. On a few occasions, they boosted the effects of psychedelics enormously and very few seeds where actually needed to create this effect.

Once a mere 30 seeds were enough to cause an overwhelming OBE on LSD, paired with the most insane visuals and a defragmentation of the mind like i have never experienced ever since. I am convinced that there is a substance in fresh morning glories, and maybe it is LSH or penniclavine, that modulates receptors that are being activated by psychedelics in such a way that it can boost the effects of other psychedelics.



How 1-acetaldehyde LSD is different from LSD:

1) You know how acid has that sudden drop off then you are back to sobriety? Instead, this lasts longer than acid and has a warm gentle transition back over a longer period. The come up is also gradual and smooth similar to cactus.

2) 1-acetaldehyde LSD is way more colorful than acid, similar to mescaline.

3) 1-acetaldehyde LSD does not have the "visual choppiness" of acid, but is flowing in the visuals.

4) LSD produces tracers with multiples of shadows of the hand, this produces not only tracers, but colored fractals and mosaics inside the tracers.

5) LSD produces "colored specs that flow in front of everything", this produces instead "fine colored rainbow reflections" that surround everything.

6) Music sounds good on acid, but music sounds great on this, like a whole nother world, similar to mescaline.

7) With 1-acetaldehyde LSD, everything seems alive and magical. Patterns & neon colors form everywhere, the shifting of textures is magical. You can lose yourself easily as the visuals seem to drag your focus in without any effort. As a result, ego death is basically spontaneous.

8] Sometimes LSD causes wandering thoughts & can seem abrasively analytical but with 1-acetaldehyde LSD there is no wandering thoughts, no tenseness or anxiety like with acid, this is deep mentally, a real gem, pure psychedelic bliss. LSD feels man-made, this feels very primitive, archaic and natural.

9) 300ug of 1-aceteldehyde LSD taken with 400g of fresh boiled thick bridgesii cactus pieces (no core, approximately 200mg mescaline) feel instead closer to the effects of 400mg + of mescaline, when also combined with 100mg to 300mg of pure THH or tetrahydroharmine (100mg is plenty !). Always take the cactus 1st, then take the THH 1 hour later --> only in that order so that the SRI which is THH does not clash with the trace maoi's in cactus.

I think this has to do with the possibility that 1-acetaldehyde LSD shifts the receptorome or radioligand binding of receptors "slightly away from 5-ht2a" and stronger towards the adrenal A2A, A2B, and A2C spectrum instead. This adrenal spectrum (A2A-A2C) is also the stronger dominance or habitat as well for mescaline & dmt & psilocin when compared to 5-ht2a, which is only midway on the spectrum, with the adrenal spectrum (associated with beauty & aesthetic enhancement) being more dominant with all these natural entheogens.

10) It is not a sacrilege to convert LSD to 1-acetaldehyde LSD cause Albert Hofmann also discovered ALD-52 at Sandoz labs. This is different from ALD-52 cause it has one extra hydrogen on the acetaldehyde adduct at the bottom indole NH group nitrogen.

12) LSD is more "analytical" and not as aesthetic, this feels more natural and is extremely aesthetic (beauty enhancing) like with mescaline.

Sample ALD-52 trip report:

hxxps://www.reddit.com/r/LSD/comments/4ynu/highly_underestimated_ald52/


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Yes, I realize it's not technically LSD but really, it might as well be. I took 300ug thinking it would be mild if anything. Granted it wasn't as intense mentally as LSD can sometimes be, but conceptually and aesthetically it is beautiful beyond anything I ever anticipated. I feel perfect. At one. Better than I've felt in so long. I thought I could never trip again on anything but this is honestly paradigm changing for me. ALD-52 should be considered just as powerful as LSD-25 although it's a lot more relaxed and somewhat forgiving. As it is probably apparent I'm still very deep into this experience and I hope this to be an open discussion to anyone who would like to be involved.

My god, I just went through multiple ego death experiences beyond anything I've ever experienced from LSD before. There are no words. I mean there are plenty of "words" but none of them mean a single thing compared to any of THAT. Dear GOD. I never expected anything like this, but I sure as hell needed it. Even if I'm the only one here to express it to, as that's realistically the truth of nature anyhow. However, anyone who felt compelled to actually read through all this insanity, I just want you to know you're beautiful and you are everything. All things are right and they always will be.

Anyway, as far as the ALD-52, I took 300ug as I said. It was amazing and stronger than I expected, however I don't think 100ug would be very eventful to be perfectly honest. If you're concerned about it being too strong 200 might be worth it but 300 was really a great amount if you ask me. Even if you haven't taken any lysergamides before ALD-52 is rather calm compared to LSD or even mushrooms for the most part. Visually though, at least for me, it was absolutely breathtaking. Colors and textures were shifting like crazy.

Everything was alive and magical. Patterns were forming everywhere. I could lose myself so easily as the visuals seemed to drag my focus in without any effort. As a result, ego death was basically automatic and I reached that point multiple times. The first time I ever experienced ego death on LSD it left me with this beautiful feeling, like a deep inner glow that lasted for months afterwards. It eventually faded and I hadn't felt anything quite like it in years, but ALD-52 brought it back, and I feel like I've awakened from a spiritual coma.

Another thing is LSD sometimes causes my mind to wander uncontrollably unless I take my own initiative to focus, especially during the come up which can also sometimes fill me with restless confusion. Once I peak everything usually evens out, but ALD-52 put me in a state of perfect clarity from beginning to end. The come up was so smooth and comfortable.

I didn't notice the come down because I actually went to sleep when I felt like it was time to do so, which was an interesting surprise. Every time I've taken LSD I've had to let it run its entire course before even attempting to sleep. Often I would have to stay up for the entire day after which is obviously physically and mentally exhausting. But once I felt like the ALD-52 had made its point I went to sleep just like any other day, and woke up the next morning fully rested and mentally clear.

Overall, it felt very natural and I never had a single moment of uncomfortability or confusion. Just pure psychedelic bliss. I mean, I've had some amazing and extremely important experiences on LSD but honestly after the other night, think I prefer ALD-52. It felt like tripping for the first time again.



Random comments found on reddit to back up my dozen experiences with 1-acetaldehyde LSD (nearly identical to ALD-52) over two years:

1) Pandemoon said:


Quote:


I dosed ALD52 like 100+ times throughout the last 4 or 5 years, in doses between 25ug and 350ug.

While ALD52 is very similar to LSD25, I think I can still see a slight difference. To me the visuals are different, especially the tracers. I can clearly see a difference there.

With 200ug+ of ALD52, when I move my hand it shows some very colorfull spirals and fractals in the tracer /smearing.

While with LSD25 it is just a mirroring effect that shows several of my hands. Not nearly as colorfull, just a non colored shadow (or several) of the real hand.

With ALD52 it's much more colorfull and intense, like painting the air with rainbow colors.

100ug or even 150ug don't really show a difference at all to LSD25, but with 300ug and above (my highest dose was 350ug) the differences are even more intense.

With 350ug I can hardly see reality anymore due to all those colorfull reflections of anything I look at.

I think the higher the dose the clearer the differences.



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2) ALD-52 is probably most similar to LSD relative to the other analogues (of which I have only tried ALD-52). The headspace is markedly psychedelic, it lasts 12 hours and the visuals are prominent enough. They seemed to take on a more flowing characteristic than LSD, to where I'd see objects form within the patterns.

3) I find it has a more mellow vibe than LSD, I'm more content to sit back and relax whereas 1p is supposedly closer to the electricity of LSD.

4) For what it's worth, I found the come down of ALD-52 to be better than LSD... it just felt more refreshing, like a warm hug and it tapers off gently whereas LSD is more of a sudden drop off into sobriety, but the actual peak of LSD feels more... alive to me. like my consciousness is oscillating at a super high vibration.

5) ALD-52 is more euphoric than LSD-25 or 1p, and I find it's also less prone to creating anxiety. Because of this, I feel like I can take much higher doses and go much deeper. I took 5 tabs and experienced absolutely no anxiety at all. I don't think I would have been able to to do the same with 25 or 1p.

6) Hmmm. I seem to get much more euphoria from ALD-52 over 1p. But yes, the anxiety levels are consistently low with this chemical. ALD-52 is an absolute gem.

7) Agree. I feel like it's a subtle power, not as forceful as 1p. But there's genuine depth to it.
I'll be the first to admit it may be placebo, but I also favor ALD-52 for this reason.

8] I am very fond of ALD-52 as well! For me, the headspace was very much like LSD#25; however, I felt like the former of the two had potential for a really crazy headspace. ALD-52 also had me seeing three different colors that I'd never seen in my life. I saw red-greens, orange-blues, and of course the fucking purple-yellows.

9) NoticesMemesOwO:
ALD is MUCH calmer than 1P in every way. 1P tends to have a shitload of anxiety on the come up and tachycardia for me and my group of friends. Its very visual but also very scary at times. especially at high doses. ALD is the best IMO. I prefer it over the real thing honestly. At high doses it was very tame, had a great visual set, and no anxiety at all. very welcoming in the way it gets you. I would pick ALD all day long, and i could take or leave 1P in all honesty.

10) Doubledog said:
My friends had some ALD52 blotters few years ago and described it as slightly more visual, and not so stimulating, and as upgraded version of LSD, but with just small difference.



11) Namaste from Shroomery (has many years experience with LSD) said:

Quote:


Tregar, I think you're on to something here. The 1-acetaldehyde LSD I made following your instructions dropping 3 hits or 300ug in 1 shot of sherry wine in the fridge with stirring once per hour was extremely chill. Soft around the edges. When I started coming down, it felt like 10 years of therapy.

I remembered good times, felt compassion. Listened to music I haven't listened to in years. Thought about friends, was at peace in a way that I haven't felt before.

The stars formed into animated constellations. My Bodhi statue began to juggle. I saw the Perseidies meteors not just out of the corner of my eyes but right over my face while lying in a hammock. Saw the entire movement from start to finish. They looked like giant arrows.

Stayed awake all day, went out to visit friends. It was very happy nostalgia. Sometimes larger doses make me totally black out. Not this time, I was awake and aware. No primal fear or paranoia.

Felt like I was still peaking seven hours after dropping. Sometimes I get a cracked out, confused feeling, not this time.

Haven't seen neon colors like that since the one and only time I was puddled.

Sunday's are generally filled with dread and depression for the following week. Experienced none of that. Just a long lasting afterglow. Still in a great mood now. I did get a pretty severe headache but I also drink like it's my job, and I am on a SSRI.

Been thinking about Ephesus and Pergamon, not sure if thats subliminal or coincidence.

Going to wait 3-4 months and repeat.

Give this a go!



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Part 4: Tetrahydroharmine receptorome similarities to mescaline; potentiates cactus & safety note
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A little off topic, but I think tetrahydroharmine is a pretty special compound. I've used 250mg of it to potentiate cactus to very strong levels, it makes a 12" medium san pedro cactus tea which may contain around 250mg mescaline feel like an X-large 12" thick san pedro cactus containing around 400mg mescaline. It makes a 12" thick bridgesii cactus feel closer to a tea made with a 12" bridgesii cactus along with an extra 6" piece.

In the data I've seen for THH, it strongly blocks serotonin just like cactus, but also agonizes the adrenal A2A thru A2C receptors (the receptors associated with aesthetics & beauty), just like mescaline has been shown to do receptorome wise, explaining perhaps why they "overlap" so well. THH being able to make mescaline in cactus feel much stronger than it really is. Anyone who has ever taken cactus or high dose THH knows the appreciation for beauty experienced is "over the top".

But you have to stagger the THH from the cactus by taking the tetrahydroharmine around an hour after the cactus is taken, that way any minor maoi's or rima's in the cactus won't interact with the SRI which is THH, which can result in a faster heartbeat for a few hours which has happened to me before...so long as you take it later, it potentiates the cactus quite incredibly...it feels like I've taken 400mg of mescaline containing cactus tea when it's really only 250mg mescaline containing cactus, and they both lasts around 6 hours with super strong activity, so they wind down at around the same time. I have around 7 months experience combining the two, giving myself around 2 weeks apart from journeys.

It works so well, I won't take cactus any other way from now on. I get much more mileage from cactus this way. Visuals and visions are insane, music is so good sounding, you would think you were an alien experiencing sound and music for the very first time, every instrument stands out on it's own, like hearing a track for the very first time.

Always take the san pedro, bridgesii or torch cactus first (they all contain trace maoi like actives)...then take the THH one hour later, in that order, then the journey is pure bliss and no negative interactions. Beautiful combo beyond belief, just like the combo of THH + LSD or THH + mushrooms.

Other topics: Alchemy chemistry fun:

How to extract 2.4g dmt from 170g bark using a 2 Liter erlenmeyer flask (heat and break resistant), post #15:
https://mycotopia.net/topic/111610-hpbcd-dmt-sublingually-active-under-tongue/

Tetrahydroharmine or THH and how to make her, Caapi visionary feminine teaching spirit:
https://www.shroomery.org/forums/showflat.php/Number/28423951/page/1

Zero nausea HPBCD or aloe vera enhanced penetration Ayahuasca capsules:
https://www.shroomery.org/forums/showflat.php/Number/28189371/page/1

Cactus tea before waterpark to beat the heat:
https://www.shroomery.org/forums/showflat.php/Number/28411312/page/4

How to make LSI or Lysergic Acid Isovaleraldemide (Greek Eleusis ancient LSD) at home from morning glory seeds (the priests used non poisonous claviceps paspali which grows on paspalum grass adjacent to Eleusis present day in the famous Rarian plane, same alkaloid profile as the sacred Mesoamerican morning glory):
https://www.shroomery.org/forums/showflat.php/Number/27850299/page/2

LSD high dose trip: 20 minute visionary visit from a dead Aztec Shaman:
https://www.shroomery.org/forums/showflat.php/Number/28451382

On my very first pan cyan mushroom trip, where I went to a house music club tripping with friends, I viewed laser light patterns on the floor of the club, where the women danced, I believe the mushrooms showed me how to form never before seen patterns, as went I went home, over the next several months, I built my own 6 channel audio generator that when these combined frequencies (3 on x channel and 3 on y channel) were sent to a laser x and y galvanometer, were able to produce brand new laser patterns such as collapsing circles and spinning lines 360 degrees which looked beyond belief in the fog as 3-d, I then went on to market these laser scanners to clubs on the strip, and they were a huge success...I owe this creative invention to the mushrooms which sparked new creative energies, way beyond thought, from a higher source where the mushrooms tap into. My love for house music stems back to those days of visiting many clubs as an entertainment laser lighting fixture creator and programmer and making friends with the many DJ's. Over the summer myself and friends were lifeguards at the local water park. But on the weekends we went to parties or house music clubs.

https://www.friskyradio.com/
https://jaytechmusic.podbean.com/
 
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I've gone over why LSA does not react with aldehydes in the manner that people claim, and there is no evidence for formation of LSH from acetaldehyde and LSA, in fact, there is no literature evidence for any amides reacting with aldehydes to form 1-hydroxyalkylamides of any sort. Also, imine/hydroxyalkylamine formation requires conditions that are free of water: aldehydes and amines do not react if they are in water solution (sherry is 78-85% water). Read about how aldehydes and amines react before making any claims. "Imine formation is a reversible process [...]" meaning the 1-hydroxyethyl product reacts with water to form the aldehyde and LSD... oopsy.

Once you start mixing in other psychedelics all scientific reproducibility is thrown out the window, (Like I mentioned in the above thread, LSD and analogues make you more suggestible so I don't really consider trip reports as reliable scientific evidence)

There was also a recent study that showed that ALD-52 and 1P-LSD and other 1-acyl-LSD analogues are rapidly metabolized to LSD and simply function as prodrugs (I.e. they don't have "magical" effects or anything unusual and are equally likely to cause a bad or good trip as LSD). So even if you did form any sort of addition product to the aromatic nitrogen it would just turn back to LSD anyway.

Also, Tim Scully and Nick Sand (the chemists who made Orange Sunshine) said that Orange Sunshine was actually just LSD, the claim that it was ALD-52 was an attempt to get out of a charge and was never proven. (source: The Sunshine Makers (great film, with Tim and Nick in it, as close as you're gonna get to an authentic recollection by the guys who actually made it), [ref1][ref2], etc.

Sorry to "harsh your buzz" but I dislike these kind of playground rumours that are often repeated and never actually proven with any sort of proper science - it's always trip reports and subjective experiences. To me, that's not enough.
 
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Also,
> adrenal A2A thru A2C receptors (the receptors associated with aesthetics & beauty),
These are absolutely not associated with "aesthetics and beauty", they are responsible for the activity of adrenaline, and α2A specifically is an autoreceptor which your body uses to sense the levels of adrenaline and either release more (α2A antagonists like yohimbine act as (fairly rough) stimulants that have a strong effect increasing heart rate/blood pressure, and α2A agonists like clonidine act to decrease blood pressure and cause sedation). Not to be confused with the adenosine A2A receptor. which is responsible for caffeine's stimulant effect (as adenosine builds up it causes sedation and caffeine antagonizes the A2A receptor to allow your body to "ignore" the adenosine and feel more awake. And there is no A2C receptor. (Just A2B).

Tetrahydroharmine does not "block serotonin", nor does mescaline. It is a serotonin reuptake inhibitor, and also a reversible inhibitor of MAO-A (which is why it potentiates psychedelics like mescaline). Unfortunately they don't mention this at all, and THH (i.e. from Banisteriopsis caapi or Peganum harmala) poses its own risks as a MAOI and shouldn't be taken lightly, and combining it with psychedelics could result in seriously bad trips if you're not prepared for it.

And what's the need for posting images of scantily clad/topless women, boasts about your inventions, and links to web radio? How do those relate to the topic at all?
 
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