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Opioids Magnesium sulphate, potentiation or reduce tolerance...

MartinFn

MartinFn

Bluelighter
Joined
Dec 16, 2010
Messages
336
Location
Europe
Hallo to all Bl mates...So, the tittle says it all. I'm on the fent patches for years, chronic neuropathetic pain. Now i stick a 100mcg/hr patch every 48hrs...and because of the tolerance, i'm still on pain. I don't take any IR meds for B/T pain, so as you can figure out, some times the things goes vvveeery fuckin bad..I've tried potentiation with CYP3A4 inhibitors, which worked very good with some of them, and nothing with some others..But it's not a healthy option, the liver...Also some other things i don't want to discuss here. Anyway, i would like to know if somebody has tried the magnesium with fent, or with other opiods/opiates, i would appreciate every option...And no, i don't forget how an idiot idea is to potentiate or abuse fent...and of course no one should try to do it..But i know my body and his reactions/responses to meds, and i respect/be careful, and go slow everytime...Thanx..:)%)


MartinFn
 
I would strongly recommend investing in Chelated Magnesium instead of magnesium sulphate.

I take it every day with all my other vitamins. I don't know if it does anything significant for tolerance prevention with fentanyl or if it would do ANYTHING to make your opioids work better, but it may be worth a shot.
 
sekio said:
Mg is not going to do anything miraculous for your tolerance.
Click to expand...

/thread

But that doesn't mean it's not worth trying! I take chelated magnesium every day with my other vitamins. I don't take it for the sake of reducing opioid tolerance as I don't believe and experiences has proven to me that it's not going to do anything significant for opioid tolerance, but these days, many people's diets are lacking in magnesium so it's just good for you in general to add it to your daily vitamins.

Note: Magnesium is best absorbed in the evening, if I recall correctly. I take half of my daily vitamins in the morning, and half in the evening with my chelated magnesium for best results. I don't notice any impact on my pain medications whether I take the Mg or not, and it hasn't ever had any impact on my pain medication (oxycodone).
 
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Ok, so, except from the point of a healthier nutrition, which is a fact, i don't think my diet gives me the amount of magnesium that is daily recommended, (and of course it's not the only one), i don't eat vegetables and enough fruits, i'm sure that i've lack of vitamins, minerals, and other "healthy" stuff, i guess you're right tricomb...But except from this point, can i suppose that taking magnesium chelated with l-theanine, maybe i'll have a potentiation about, let's say, 10%, or something?..Or maybe i should try the DL-Phenylalanine...Anyway, thanx to everybody, mates...%)


MartinFn
 
MartinFn said:
Ok, so, except from the point of a healthier nutrition, which is a fact, i don't think my diet gives me the amount of magnesium that is daily recommended, (and of course it's not the only one), i don't eat vegetables and enough fruits, i'm sure that i've lack of vitamins, minerals, and other "healthy" stuff, i guess you're right tricomb...But except from this point, can i suppose that taking magnesium chelated with l-theanine, maybe i'll have a potentiation about, let's say, 10%, or something?..Or maybe i should try the DL-Phenylalanine...Anyway, thanx to everybody, mates...%)


MartinFn
Click to expand...

I have a bottle of D-Phenylalanine that I have not opened yet, I am definitely going to give that a try later but with finals fast approaching, I'll probably end up taking my Desoxyn, and methamphetamines are contradicted with D-Phenylalanine, I've heard it can potentiate the FUCK out of meth, and that is the LAST thing I need. But when school's out I'm definitely going to give it a trial, since I don't forsee needing Desoxyn during that time period quite unlike pain management which I require 24/7.

Try the Chelated Magnesium, it's worth a shot! I wouldn't be expecting sunshine and rainbows from it but if it brightens your day even the littlest bit it's worth adding to your diet because most people's diets are deficient in Magnesium.
 
methamphetamines are contradicted with D-Phenylalanine, I've heard it can potentiate the FUCK out of meth, and that is the LAST thing I need.
Click to expand...

I find this very, very hard to believe, as D-PA is essentially centrally inactive (wrong isomer to turn into dopamine)
 
So tricomb, if it will brighten my day, it's def worth a shot, i think i'll try it...you def say the chelated, not the sulphate, heh? And smth else i wanna ask you, as you take a lot of vits. Some "junkie myths" says that vit C, and maybe other vits, makes the opies weak..i have chronic pain, and i don't eat all kinds of food, vegetables etc., i'm not feeding as i should..but i don't wanna take multivitamins and make the fent weaker, (well, as a matter of fact, i think that these junkie myths are bullshits, but i would be more sure and comfortable, with your configuration, as you take the vitamins with your opiates, i think roxycontin, so you know for real..).

I had read a previously post you wrote the nutrition supplements you take, i don't remember well, i think l-lysine, or choline, i don't know..
What would you suggest me to take, as i've written above about my situation, of course i know i'm not talking about day/night changes, just a lil help, you know..
Tricomb, sorry if i put you in trouble, but i trust you, i think you've got a lot of experiences, though you're younger than i am (37)...
Thanx%)



MartinFn
 
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Vitamin c is ascorbic acid , I think acidification of the body might speed up excretion of certain substances I know it applies to amphetamines not sure if it works the same for opiates.
 
the body has a means of buffering out acidic compounds rather quickly so vitamin c isnt going to make a difference unless the amine was taking at or around the same time as a lot of it.
 
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