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  • Trip Reports Moderator: Cheshire_Kat

(Lyrica / Pregabalin / 500+ mg?) - First Time - Crazy fun drug

Christopher Sophia

Greenlighter
Joined
Apr 19, 2013
Messages
6
Location
Hyperspace
I posted this report this morning on several different forums. I think you'll find it interesting.

I have horrible chronic pain from arthritis in my neck and chronic headaches. I've been prescribed since I was 16 just about every pain med out there: Fioricet, Oxycontin, Dilaudid, Tramadol, Midrin, Imitrex, various NSAIDS, etc, etc, etc. Nothing has ever helped for more than a month and then the tolerance kicks in. Soon even the highest doses do nothing, and I switch to something else.

Lyrica is about the only thing I've never tried, so my doc gave me a script. Well, my stupid insurance refused to pay for it, so I called the drug company to see if they could help. They had me give them my info, and mail them the actual prescription. So they just called me and said that they would mail me 90 days of Lyrica right to my house for free, and that it shipped two days ago and should get here tomorrow. Every 90 days until December 2014 I will get another free shipment of 3 months worth of pills! The doc only gave me 50mg twice a day, which from what I've heard is the lowest dose, so I doubt that will help considering my natural tolerance to everything. I've heard of people taking up to 1500mg to get high, so it's relatively safe in high doses.

So my Lyrica shipment came yesterday, so I took it for the first time. I started with 300mg so I could assess how I reacted to it before going higher. Within an hour I was really high! This is a fantastic drug, and from reports I've read, completely underrated.

I've been awake all night basically in a tripped out Dissociative state. I talked to someone online last night who said Pregabalin is completely water-soluble, and can be snorted or injected. He told me that he shoots it and the powder completely dissolves on the spoon. He said the initial rush is amazing and cannot be compared to anything else because it's totally unique. He also said that even after doing one 200mg shot he gets tripped out for almost 6 hours.

I've been awake since 6:00 AM yesterday snorting 400mg of the Pregabalin every 3 hours.

Pregabalin is totally trippy in high doses, and the closest comparison I could make to another drug is if you took a 1st Plateau dose of DXM and took GHB throughout the trip. But even this comparison doesnt explain it. It's really easy to snort because it comes in tiny little capsules filled with a very fine powder that has almost no burn or taste at all. This is definitely one of my new favorite drugs, and the best part is the drug company mailed me 180 50mg capsules for free! I'll get another shipment every 3 months until December 2014, and then I have to get a new prescription from a doctor.

The effects I've been experiencing are:

-Intense music and motion euphoria
-visual distortions
-increased flow of thoughts
-enhanced creativity
-a slight pleasant drunken feeling
-difficulty walking straight
-physical drowsiness, but intense mental energy so much so that sleep is hard even though I feel drunkenly drowsy
-not a single unpleasant side effect

So basically I <3 this stuff! It is really, really good. I highly recommend it.

Keep in mind that my reaction to it may be a little different than the average person because I take 450mg of Venlafaxine daily, as well as 400ug of Huperzine A, which is a mild NMDA antagonist, and 600mg of Magnesium Glycinate, which is also a mild NMDA antagonist, so the things could all potentiate the Pregabalin.

I think the medical establishment is downplaying Pregabalin' s effects, which is fine with me because it's less restricted than other things. I just find some of the official information about it curious. Check this out:

This is from Wikipedia:

Misuse

Pregabalin is a Schedule V drug, classified as a CNS depressant. The potential for abuse of pregabalin is less than the potential with benzodiazepines; additionally the mild euphoric effects of pregabalin disappear with prolonged use.

Mild euphoric effects? That's just a blatant lie. It has intense euphoria as well as unique psychedelic/dissociative effects. And as far as the statement that the effects go away in time, implying tolerance, read the following from the same article:

Quote:
Long-term trials have shown continued effectiveness without the development of tolerance

Whoever wrote this totally contradicted themselves. But anyway, my assessment of Pregabalin is that it is a safe, powerful, unique, easy to injest, and easily obtained. I love it!

Tagged by Xorkoth
substancecode_pregabalin
substancecode_gabapentinoids
explevel_firsttime
exptype_positive
exptype_glowing
roacode_oral
 
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^The thing is, euphoria is considered a side effect and independent from the therapeutic effects.

Glad you had a good time, though. I'm ordering a bag of this stuff soon.

I would consider starting at subthreshold doses next time you try a new drug ... jumping in at 300mg was risky.
 
Lyrica is th most continually surprising pharmaceutical I've ever had the pleasure to ingest.
 
Hallo people..
I really don't wanna dissapoint you, but i've used lyrica for "recreational effects", and yeah, i also find it good (but not as good as you describe). The doses i took was from 600-900mg, (but i take 450mg daily as it is prescribed; (chronic pain) for more than 5 years). So at about 900mg i found some mild euphoria, some mood increase, but not something like the euphoria that strong benzos like triazolam, flunitrazepam, even a good big dose of diazepam usually gives. But the negative is not this ..once time i took 1100mg, cause i found that 900mg didn't get me high. So it worked, yeah, it made me high for one day. BUT the next day, about afternoon time, i started to get opiate W/D's symptoms, you know, the fuckin feeling of being totally sweat in a second, and the next minute i got chills8(, i've been using opiates for years and i really know the withdrawl feelings very well, you know, you can't sleep, being hot and cold at the same time, fuckin depresion and other "lovely":X stuff like that..and even the benzos i took couldn't help me much..Don't wanna rain on your parade, i just write my own experience to keep an eye on this, lyrica is surely not the "great drug"...

Christopher Sophia, maybe the venlafaxine and the other stuff you take, makes lyrica work great, but just in case, remember to "don't play all your cards"8), and beware of tolerance, cause it is increased...really..There's a mega-thread in OD, take a look..:)

Again, i'm sorry if i dissapoint you, but i don't want anyone to go through the W/D i went, even if it doesn't last more (i took opiates and in half an hour it was gone..;)), i'm sure you know what i mean.
With all my love, to all Bl'ers%)


MartinFn
 
I tried Lyrica for chronic pain (peripheral neuropathy, arthritis and stenosis) and found it didn't do anything that gabapentin (Neurontin) didn't do gab is a lot cheaper. Wish I got more from it than I do.............I am totally agog that folks get a high from these things........then I could at least smile a bit through the discomfort/pain. Am on 2400/day. Anyone know the max on this stuff?
 
I don't want to rain on anyone's parade either...but Lyrica is a dangerous, very addictive drug w the worst, and most brutal w/d for me. It's like being in multiple kinds of w/d at once...it mimics opiate w/d, benzo w/d. You get this horrible sweat, that for me, was even worse than opiate w/d, you're mentally freaking out w the worst anxiety attack that won't stop...you stay in a fight or flight state, and cannot relax....read the thread "Lyrica Withdrawal" on this website. It will explain this drug. Be careful, and taper down. You don't want to experience severe Lyrica w/d. Best wishes to all.
 
I don't want to rain on anyone's parade either...but Lyrica is a dangerous, very addictive drug w the worst, and most brutal w/d for me. It's like being in multiple kinds of w/d at once...it mimics opiate w/d, benzo w/d. You get this horrible sweat, that for me, was even worse than opiate w/d, you're mentally freaking out w the worst anxiety attack that won't stop...you stay in a fight or flight state, and cannot relax....read the thread "Lyrica Withdrawal" on this website. It will explain this drug. Be careful, and taper down. You don't want to experience severe Lyrica w/d. Best wishes to all.

How high were you on lyrica (dosage wise) and for how long? Yes, it can be horrible if stopped too fast or tapered down too abruptly, but if done correctly, it even possible to withdraw benzos with it (just my opinion). I've gone from 600mg/d that I've took more than six months down to zero within three weeks or so ... if you're experiencing w/d, considering getting on Memantine, an NMDA antagonist - a class of medication that alleviates glutamatergic overexctitation. Go up with the dosage to 40 mg/d or so, maybe you're deeling stoned at first, but the w/d feelings will disasppear. Then you're ready to further taper down with Lyrica ... keep the Memantine for several weeks after the Lyrica is away, then taper the Mem. away ... and you'll be fine. Btw, the same could be work for benzo's and even for opiates and stimulants (as it did for me!) ...

Dependendies are not that kind of one way routes the docs want us to believe that they do ... they are just one more mechanism of our bodies to adapt, and there are ways to help'em to reverse these pathways with time and knowledge ...
 
Taking Lyrica for the first time this evening and Im wary of taking even the 300mg ChristopHer Sophia initially did. I've had 200 and will see how it goes. Had 125 last night and didn't notice much if anything. The highest dose I'm prescribed is 50 at a time and this in order to cope with evening overstimulation by Strattera and opiate withdrawal associated with tapering off the last couple of mg of bupe. [/I].
..aand we're back 2 hours later. Nothing much at all other than perhaps some difficulty with my eyesight - the computer screen is a bit blurred. This might jibe with CS reported feeling of 'pleasant drunkenness'. I may try 300 tomorrow night and report on that too. Don't know if anyone will read my little blog tucked away on this far corner of a particular thread on a particular med but I like writing it

Back again about 3 weeks later. I took 325mg tonight having had none for the 3 weeks and don't notice anything..could this be due to the fact that I'm on a little bit of buprenorphine (1mg) or does Lyrica's effect vary from person to person? Doesn't do much for me
 
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I have bad nerve neck pain issues for a while and went to the doc last week and wanted Lyrica and he never wanted to give it to me with some or other random excuse. Dammit.
 
If you get long-term addicted, look forward to the 10-day benzo/opiate like withdrawal. Which will very likely involve a desperate visit to the ER which will do nothing for you. Keep benzos and kratom on hand, FFS.
 
I've gotten samples from my dr to use off-label for anxiety. I felt mildly drunk at regular doses (50mg 3x/day). Not much enjoyment with the visual distortion.
 
I happened upon some of these once and I absolutely loved the high, it was really, really good. It was like super-phenibut, one of the best euphoric feelings I've felt. I found it would barely work the next day though. I also found that it completely masked opiate withdrawal, at least for kratom (I used to dose kratom 3-6 times a day at 6-12 grams and did so for 6 years straight). I'd like to find some more.
 
How high were you on lyrica (dosage wise) and for how long? Yes, it can be horrible if stopped too fast or tapered down too abruptly, but if done correctly, it even possible to withdraw benzos with it (just my opinion). I've gone from 600mg/d that I've took more than six months down to zero within three weeks or so ... if you're experiencing w/d, considering getting on Memantine, an NMDA antagonist - a class of medication that alleviates glutamatergic overexctitation. Go up with the dosage to 40 mg/d or so, maybe you're deeling stoned at first, but the w/d feelings will disasppear. Then you're ready to further taper down with Lyrica ... keep the Memantine for several weeks after the Lyrica is away, then taper the Mem. away ... and you'll be fine. Btw, the same could be work for benzo's and even for opiates and stimulants (as it did for me!) ...

Dependendies are not that kind of one way routes the docs want us to believe that they do ... they are just one more mechanism of our bodies to adapt, and there are ways to help'em to reverse these pathways with time and knowledge ...

Do you mean that memantine alone worked for you for opiates? Or that you did Lyrica and then memantine for the Lyrica? I found Lyrica to mask opiate withdrawal quite well, but I've never had memantine
 
I found some trial offers in the house and decided to pop a few. I don't know what my they were or how many I did. I did it around 9:00pm and nothing ever happened that night so I went to sleep. Well when I woke up the next morning I felt like I was drunk as fuck. I don't like that feeling so lyrica sucks ass IMO haha. Won't be doing that shit again
 
Well you may have had too much, especially since you don't know what dose they were or even how many you did (??). It's a real drug, it's easy to have too much, why wouldn't you even take note of how many you ate?
 
Well you may have had too much, especially since you don't know what dose they were or even how many you did (??). It's a real drug, it's easy to have too much, why wouldn't you even take note of how many you ate?

Well I knew what mg they were at the time and I think I may have taken 4 or 5 capsules. I wanna say they were like 50mg caps. I only did it cuz I was going through opiate withdrawals and just wanted to et high to take my mind off the withdrawals and I had no intention of doing lyrica again so that's why I didn't take note of how many I ate. I did do it again though about a year ago. They were 50mg and I only are 2 and the effects were easier to handle and wasn't as intense. Still made me feel like I was drunk, idk why I tried it again cuz I hate the feeling of being drunk. I don't even like drinking. It was just the addict in me wanting to get high
 
Well I knew what mg they were at the time and I think I may have taken 4 or 5 capsules. I wanna say they were like 50mg caps. I only did it cuz I was going through opiate withdrawals and just wanted to et high to take my mind off the withdrawals and I had no intention of doing lyrica again so that's why I didn't take note of how many I ate. I did do it again though about a year ago. They were 50mg and I only are 2 and the effects were easier to handle and wasn't as intense. Still made me feel like I was drunk, idk why I tried it again cuz I hate the feeling of being drunk. I don't even like drinking. It was just the addict in me wanting to get high

It makes you feel drunk because Pregabalin, Alcohol, and Benzos all affect the GABA receptors... The weird thing about Lyrica is that it doesn't alter the chemicals in the brain associated with GABA and is also not metabolized by the liver. It's a very confusing drug but damn it's good! Remember that Lyrica and Neurontin gives everyone different effects in the aspect of the severity of the high and the ability for it to actually work. It's a hit or miss, either you like it or you don't. It could even be possible that it can do absolutely nothing to you even in high doses! I guess some people just don't respond to it...
 
pregabalin and gabapentin are gaba agonists and as such will do nothing if there is not a gabaergic drug involved unless you're a total lightweight or do something stupid like shoot it up - the high associated with pregabalin is considered by the researchers to be like valium which means if you get off you're a douche
 
That is not correct, sorry...

Pregabalin, gabapentin, being gabapentinoids despite the gaba in the names are NOT gaba agonists. They are gaba analogues but act as VDCC's: they block calcium channels and influence the way neurotransmitters like serotonin and substance P act. Also they influence a decarboxylase enzyme that balances glutamate with gaba - that is the only indirect way GABA levels are elevated vs glutamate levels.

I get pregabalin prescribed, and even before I had a script I tried it recreationally at higher doses like 300-450 mg which I really liked - but the 'magic' fades. Don't be silly to write off the recreational value and definitely don't substantiate your claim with something about gabaergic drugs that isn't even true. I take it you never tried it at sufficient doses then..
 
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