During the trip does anything unusual happen which might be encouraging?
If so I would recall this encouraging thing as a takeaway with great value.
If nothing encouraging is happening on the trip, i.e. it mostly intensifies unhappiness, do not continue tripping without professional assistance.
In some ways tripping is like having a personal particle accelerator, you can smash through personal conceptual barriers,
but if you are doing things that are not beneficial then, you are doing them in a very amplified way, and will need help to get better on track.
I hear that good stuff is happening in NYC University with regard to psychedelic therapy.