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Lysergamides LSD can be boiled and vaped

red22

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Nov 23, 2009
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At least 50% of LSD-25 remained in the active form even after baking the LSD-25 in a batter made from Commercial Bisquick at 300°F for one hour and freezing it for several weeks (36). Boiling a solution of 1.0mg/ml of LSD-25 in the dark up to 4 hours did not lead to a significant destruction of the LSD-25. However, LSD-25 is very sensitive to light. Its photodecomposition has been described by Niwaguchi and Inoue. Further details of the destruction of LSD-25 by ultra-violet light is described in the section under assay of LSD-25.

36. Gettner, H.H., Rolo, A. and Abramson, H. A. J. Psych. 75, 35 (1970).

39. Inoue, T., Nakahara, Y. and Niwaguchi, T. Chem. Pharm. Bull. 20, 409 (1972).

LSD: A Total Study. D.V. Siva Sankar. 1975. PJD Publications Ltd.: Westbury, NY. INTRODUCTION / EARLY HISTORY OF LSD, page 50


Everyone thinks LSD can't be vaped.

And they're wrong.

Yes, heat degrades LSD, but it doesn't destroy it.

All that happens is the effects are immediate & the high lasts 3-4 hours instead of 12. Now you know ;‍)

@FatherMcKennaa. 2025-09-09. twitter

The source is a psychedelic researcher that I trust.

I recognize this sounds impossible, but it has been tested.

follow-up comment


Update:

Quotes

I have not, got this info from
@Josikinz

FatherMcKennaa. 2025-09-11. twitter

Reply to "Have you tried this ROA?"


I am a professional psychedelic researcher. I tried vaping LSD and it worked. The psychedelic subculture has a big problem with just saying things don't work, without ever trying it for themselves. Then they repeat it to others, who spread it further... without trying it...

Josikinz. 2025-09-10. twitter

oh and to clarify, the onset was instant, rose over a few minutes, then lasted a couple hours before dropping off.

Josikinz. 2025-09-10. twitter


LSD tab into vape juice (PG or VG) left for a day or two.

FatherMcKennaa. 2025-09-11. twitter

Reply to "What is the process for vaping it?"
 
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Damn, ive always wondered what injecting LSD IV would be like, vaporizing it seems promising too.

Im doubtfull of the claim that it only lasts 3 - 4 hours though, since IV LSD still has a long duration and inhaling a substance does not differ by much from its duration intravenously, often times IV is even shorter than inhaling a substance

Are there any actual user reports on vaporized LSD?
 
Acid chemist and strange ass person Casey Hardison claims to have vaped freebase LSD if I'm not mistaken. When I'm back in possession of some, I may put it in a nebulizer with fresh tubing and see what happens.
I will be awaiting your report eagerly 🫡
 
I wonder if you can smoke a quarter blotter to good effects.
 
I wonder if you can smoke a quarter blotter to good effects.
No, not at all. I know people that attempted that with multiple tabs sandwiched between layers of weed when they were young and dumb; no effects whatsoever.

If consumption by inhalation is truly possible, then it must be properly *vaped*, not smoked. And if you noticed in the parent post, much of the compound is lost due to the heat. So your dose would need to be much greater than that.
 
I just checked and yeah, freebase LSD has a melting point of 80-85C (although that wide range does question the purity of the samples tested) but is it efficient?

While I can absolutely believe Casey would know and would try - it's EXACTLY what he would do, but is it efficient?

BTW Sadly, Casey is another example of someone who broke rule 1 (and several others). I even pointed out that under UK law, analogues were legal so why not make those? His answer was 'well, I wanted to make LSD'.

Like Owsley, he wanted the cache of being known to have done it. And got a good 13 years and 8 months (20 but in the UK good behavior can reduce that by a third) to figure out if it had been worth it. More recent accounts don't show him in a good light. Living off that dwindling cache is a bit sad.
 
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I just checked and yeah, freebase LSD has a melting point of 80-85C (although that wide range does question the purity of the samples tested) but is it efficient?

While I can absolutely believe Casey would know and would try - it's EXACTLY what he would do, but is it efficient?
Almost certainly inefficient imo, but only testing could really tell.
 
Yall want to hear the story of my friends?

One thanksgiving, while my friend was out of town, his roommates opted to use the aluminium tray (that he used to lay pages of LSD) to cook turkey i believe.

Everyone got super high about 30 min into dinner. Thank god they were aĺl pretty experienced.

LSD is somewhat fragile, ive degraded liquid in hot cars sadly, but a bird told me that as the D-ISO-LSD percent increases the degradation rate slows down. Ive def eaten poorly stored LSD, and while it was certainly active, its effects were different. Ive also experienced this with AL-LAD.
 
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Yall want to hear the story of my friends?

One thanksgiving, while my friend was out of town, his roommates opted to use the aluminium tray (that he used to lay pages of LSD) to cook turkey i believe.

Everyone got super high about 30 min into dinner. Thank god they were aĺl pretty experienced.

LSD is somewhat fragile, ive degraded liquid in hot cars sadly, but a bird told me that as the D-ISO-LSD percent increases the degradation rate slows down. Ive def eaten poorly stored LSD, and while it was certainly active, its effects were different. Ive also experienced this with AL-LAD.
glad all that residue did not get totally wasted but the guests did instead
 
Yall want to hear the story of my friends?

One thanksgiving, while my friend was out of town, his roommates opted to use the aluminium tray (that he used to lay pages of LSD) to cook turkey i believe.

I expect that with enough soap and water, as would be used to properly clean the tray before use, that the LSD would be all but gone, so all I can say is eww gross!
 
Quotes

I have not, got this info from
@Josikinz

FatherMcKennaa. 2025-09-11. twitter

Reply to "Have you tried this ROA?"


I am a professional psychedelic researcher. I tried vaping LSD and it worked. The psychedelic subculture has a big problem with just saying things don't work, without ever trying it for themselves. Then they repeat it to others, who spread it further... without trying it...

Josikinz. 2025-09-10. twitter

oh and to clarify, the onset was instant, rose over a few minutes, then lasted a couple hours before dropping off.

Josikinz. 2025-09-10. twitter


LSD tab into vape juice (PG or VG) left for a day or two.

FatherMcKennaa. 2025-09-11. twitter

Reply to "What is the process for vaping it?"
 
Last edited:
Damn, ive always wondered what injecting LSD IV would be like, vaporizing it seems promising too.

I've shot LSD few times. Rush is intense then you get a regular LSD trip maybe shorter.. I shot too much once and had to take a tonload of clonazolam to abort the trip the world was just melting I couldn't see further than my nose it was damn crazy, very intense . It was liquid drops of something like 150microns each.
 
I've shot LSD few times. Rush is intense then you get a regular LSD trip maybe shorter.. I shot too much once and had to take a tonload of clonazolam to abort the trip the world was just melting I couldn't see further than my nose it was damn crazy, very intense . It was liquid drops of something like 150microns each.
That sounds intense to say the least, I wonder how intense a full milligram IV would be, probably just get blasted into lysergaland instantly 😵‍💫
 
That sounds intense to say the least, I wonder how intense a full milligram IV would be, probably just get blasted into lysergaland instantly 😵‍💫
That would be a lot, got to be really tough mentally, experienced to get through it . I think I did half of that and frankly it was too strong not great set and setting either
 

I found this and thought people interested in LSD would find it interesting.

I've not once been tempted to produce LSD or even an homologue. The reason is simple - while it's quite simple with the modern peptide coupling reagents, there are reckoned only to be two or three labs producing ALL of the LSD (and homologues) in the WORLD at any given time. Even that Dutch lab making legal homologues got busted. My guess? Some ended up in the USA and the DEA just don't care where on earth someone is - if something 'illegal' winds up in the USA, they go after whoever it is wherever they are. Worse, they will hound you for the rest of your life. Look at David McMillan. He had served his time and was engaged in a new career doing something unrelated to drugs... but the DEA tried to engineer his being extradited to Thailand for execution.
 
I've not once been tempted to produce LSD or even an homologue. The reason is simple - while it's quite simple with the modern peptide coupling reagents, there are reckoned only to be two or three labs producing ALL of the LSD (and homologues) in the WORLD at any given time. Even that Dutch lab making legal homologues got busted. My guess? Some ended up in the USA and the DEA just don't care where on earth someone is - if something 'illegal' winds up in the USA, they go after whoever it is wherever they are. Worse, they will hound you for the rest of your life. Look at David McMillan. He had served his time and was engaged in a new career doing something unrelated to drugs... but the DEA tried to engineer his being extradited to Thailand for execution.
From what I heard, the Dutch lab was just caught in the crossfire. I hope there is some more information for when the interview of Alexander Stratford with Hamilton Morris finally gets released. Do note that they resumed operation after the bust, and only stopped their work completely at the beginning if this year presumably due to annoyance with the ever stricter analogue laws. From what I've heard, a shop that was selling their products was selling fentalogues as a side hustle to the US via darknet markets. From what I know, the Dutch lysergamide lab worked completely within the confines of the local law.

Current trends in precursor availability suggest a lot more clandestine laboratories having the ability to make small batches of lysergamide these days. Of course some chances are foolish to take, never forget that, and wise you seem for your decisions.
 
I wonder if it would work to mix with vapejuice and then use a vapepen?

Maybe drop a few drops of liquid acid in a glass container and let it evaporate before mixing in some vapejuice?
 
It's of interest to me that a few sources seem to parrot the fact that when a pure sample of a stable salt of LSD is shaken, it displays triboluminescence. But I checked the work of Shulgin, Nichols and others, none of whom mention the fact. It seems to be one of those statments that due to it being appealing, appears to have become an accepted fact. To the best of my knowledge Casey didn't mention it and he certainly had enough pure compound to assert the fact and is someone I feel WOULD highlight the fact.

I've just noted that it seems to be mentioned in many places, some even give a reference. But you check the reference and it isn't mentioned. Shulgin uses the word 'sparkle' as part of a subjective experience, not as evidence of a physical phenomenon.

Without a doubt nothing matches LSD for the sheer bulk of the fokelaw surrounding it. All manner of false information.
 
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