LSD and Clozapine

[D7CE]

I'm guessing this combination will cause psychedelic effects to be decreased or nonexistent all together. Anyone done it before or have any ideas on what will happen? Thanks for whatever you contribute.

 

[Indole]

Clozapine is an antipsychotic with antagonistic properties at many of the receptor sites that LSD is known to bind to. So yes, there would be hardly any psychedelia if any.