Ooo, yea that scenario does sound bad, Wiz. I would only consider doing the acid first, then maybe after that hit a plauteau for a while adding a more typical 175mg of methylone. But in the reverse order after being up all night, well your neurotransmitters are gonna be pretty depleted anyway at that point, struggling with normal activation processes, let alone adding the hyper-activity triggered by the acid. I can well imagine that the LSD felt harsh under those circumstances, like an auto engine trying to run with a clogged air filter or low oil or doggy fuel injectors or something. The energy of the core fuel burning etc. will still force the system to run, but, um, not so well.
So far as doing methylone with LSA I would have to suggest this is a BAD idea. My experience with LSA was limited to my first year in college when I was just becoming interested in psychedelics and wanting to try them but had no sources for real LSD or shrooms, so used MG and HBWR seeds in a sort of kitchen-extraction to see what they would do, and I didnt care for it much... it was OK to get an initial feel for what that "sort" of thing might be like, but I could tell it was rather a sub-optimal method. VERY harsh on the stomach (frequent vomiting), which would be a bad thing to add methylone on top of as it can cause its own stomach issues. And mainly the "dirtiness" of the LSA high felt like it had jagged edges and seemed to cause an increase in heart rate and stress on the cardiovascular system, compared to LSD and shrooms which have much much less of that... and adding Methylone in a situation where you have a rapid shallow heartrate and even some heart rhythm irregularities due perhaps to LSA I would guess would be uncomfortable at the least and possibly even dangerous.