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LOW dose phenylethylamine for social phobia

D

Diego222

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Joined
Oct 19, 2009
Messages
42
Hi guys, I am considering trying selegiline with PEA in very low dose of 60-100 mg daily. I am suffering from social anxiety and I am trying to come up with this combo for using in exposure therapy of social situations.

My goal is slight mood lifting, motivation, and being a bit more talkative. I'll be very careful, I'll keep the dosage low. My goal is not to get a high off it.

I am considering on using 2.5 mg of selegiline, 2-3 times a week + 60-100 mg of PEA daily.

What do you think about It ?
 
PEA is just not going to last long enough to be useful... its not gonna work man.. It'll make you "high" for like 15 minutes then you'll come down and need to keep taking it etc.. just get some Adderall or something (without the deprenyl)
 
What do you think about Desoxypipradrol ?

is a stimulant, dopamine reuptake inhibitor afaik. Its active at doses of few mg and has a long half life of maybe 12 hours or more.
 
yaesutom said:
PEA is just not going to last long enough to be useful... its not gonna work man.. It'll make you "high" for like 15 minutes then you'll come down and need to keep taking it etc.. just get some Adderall or something (without the deprenyl)
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My regiment is based on this study:

J Neuropsychiatry Clin Neurosci. 1996 Spring;8(2):168-71
Sustained antidepressant effect of PEA replacement.
Sabelli H, Fink P, Fawcett J, Tom C.

Rush University and the Center for Creative Development, Chicago, Illinois, USA.

Phenylethylamine (PEA), an endogenous neuroamine, increases attention and activity in animals and has been shown to relieve depression in 60% of depressed patients. It has been proposed that PEA deficit may be the cause of a common form of depressive illness. Fourteen patients with major depressive episodes that responded to PEA treatment (10-60 mg orally per day, with 10 mg/day selegiline to prevent rapid PEA destruction) were reexamined 20 to 50 weeks later. The antidepressant response had been maintained in 12 patients. Effective dosage did not change with time. There were no apparent side effects. PEA produces sustained relief of depression in a significant number of patients, including some unresponsive to the standard treatments. PEA improves mood as rapidly as amphetamine but does not produce tolerance.
 
Diego222 said:
My regiment is based on this study:

J Neuropsychiatry Clin Neurosci. 1996 Spring;8(2):168-71
Sustained antidepressant effect of PEA replacement.
Sabelli H, Fink P, Fawcett J, Tom C.

Rush University and the Center for Creative Development, Chicago, Illinois, USA.

Phenylethylamine (PEA), an endogenous neuroamine, increases attention and activity in animals and has been shown to relieve depression in 60% of depressed patients. It has been proposed that PEA deficit may be the cause of a common form of depressive illness. Fourteen patients with major depressive episodes that responded to PEA treatment (10-60 mg orally per day, with 10 mg/day selegiline to prevent rapid PEA destruction) were reexamined 20 to 50 weeks later. The antidepressant response had been maintained in 12 patients. Effective dosage did not change with time. There were no apparent side effects. PEA produces sustained relief of depression in a significant number of patients, including some unresponsive to the standard treatments. PEA improves mood as rapidly as amphetamine but does not produce tolerance.
Click to expand...

Hmm, does it say how the authors structured the protocol for this study? I won't be able to look at it until at least tomorrow, but depending on the methodologies they used I don't know how much weight I would put behind it.
 
Diego222 said:
What do you think about Desoxypipradrol ?

is a stimulant, dopamine re-uptake inhibitor afaik. Its active at doses of few mg and has a long half life of maybe 12 hours or more.
Click to expand...

Agree, but I wouldn't say this helped me 'talk' more. Was very good for finishing papers, as I stayed up for 69 hours straight, writing 30+ pages while still maintaining school fine. Slept for 10 hours afterwards, and felt fine.

I dissolved 100mg in 100ml's of destilled water, and took 2.5-3.5ml (= 2.5-3.5mg) every 6 hours to maintain good energy, without overdoing the speedy part. Was great, highly recommend it. I was feeling kinda weird at the last of the sixty hours, but I'd take that as a natural side-effect from lack of sleep.


For "talking" more and being more social I'd recommend Modafinil. It maintains my focus greatly, while staying subtle and barely noticeable. Like focus and sleep in a tablet! 150-200mg worked at mornings for me.
 
Repulse said:
For "talking" more and being more social I'd recommend Modafinil. It maintains my focus greatly, while staying subtle and barely noticeable. Like focus and sleep in a tablet! 150-200mg worked at mornings for me.
Click to expand...

Modafinil is too expensive for me :

Provigil (modafinil) - € 135.00
Alertec (Modafinil) - € 76.55
 
Is possible to extend the duration of PEA + selegiline combo effect ? Need I to take higher dose of PEA or Selegiline to extend too short time of duration, or something else ???
 
I would advise against MDPV for your purposes... it is VERY hard to not start, um, LIKING it just a little too much. I and everyone else I know who really thought it was a great stay-awake clear-head-inducing substance (used in beneficially TINY amounts of 4-8mg insufflated) ended up noticing and enjoying recreational aspects of even the tiny doses needed for wakefulness, and hence ended up becoming very habituated on it. To the degree that when you DONT use it you start to get very lethargic and slow, uncontrolibly sleepy, and are thus unavoidably drawn towards using it multiple times every day for many days in a row. When you start to try reducing dosage you get slammed with the coma-like lethargy and thus feel you have no choice but to keep taking it... Only solution is to reduce dose bit by bit then finally quit cold turkey but still have to endure like a week or so of 20 hrs/day of sleep or highly lehtergic downtime.

NOT recommended. And if you do try it for recreational or VERY temporary (like one weekend) of extended wakefullness... STOP STOP STOP after 2 days of redosing, or trust me, you will be VERY sorry in the end. Nice substance for a couple days, but it has POWERFUL claws that it will hook into you but good, without question if you use it more than 2 days in a row.
 
christ...I don't even think that benzodiazapines should be used to treat the disorder more often than for especially daunting occasions.

CBT is the way to go for social anxiety. We as of yet lack effective long-term medication for it.
 
Diego222 said:
Hi guys, I am considering trying selegiline with PEA in very low dose of 60-100 mg daily. I am suffering from social anxiety and I am trying to come up with this combo for using in exposure therapy of social situations.

My goal is slight mood lifting, motivation, and being a bit more talkative. I'll be very careful, I'll keep the dosage low. My goal is not to get a high off it.

I am considering on using 2.5 mg of selegiline, 2-3 times a week + 60-100 mg of PEA daily.

What do you think about It ?
Click to expand...

If you are suffering from social anxiety, which is a mental health issue, you will do well to avoid recreational substances. Your best best would be to seek professional help in the form of therapy or therapy combined with medication treatment. If you have difficulty obtaining these services you could probably benefit from all of the information and help available at www.nami.org. Messing around with recreational substances will only make your anxiety worse.
 
I am considering on using 2.5 mg of selegiline, 2-3 times a week + 60-100 mg of PEA daily.
Click to expand...

This will exert an effect for ~one hour, and you will feel high for that hour. This could only benefit controlled exposure therapy, and even then, a benzo would be more appropriate.

ebola
 
ebola? said:
christ...I don't even think that benzodiazapines should be used to treat the disorder more often than for especially daunting occasions.

CBT is the way to go for social anxiety. We as of yet lack effective long-term medication for it.
Click to expand...

This.

Stimulants increase focus and stamina. They definitely don't take away anxiety.

Benzos relax you, and do take away anxiety, but they're a bitch of an addiction, and your symptoms will come back whenever you quit.

There are many mental health professionals who believe that people with social phobias should abstain from all drugs. A small but vocal minority swears by using SSRIs to treat it.
 
PEA did nothing for me. Both meth and d-amp reduce my anxiety in small doses because i have thought disorder and ADD, which cause me a lot of functional trouble normally and thus create anxiety

not to say stims are perfect. they have their drawbacks for sure if used often

the one drug that has worked wonders for me, without apparent side effects, is lyrica. unfortunately i live in the States and can't seem to get more of it

i was on benzos for years and have lasting problems from them which made my anxiety and memory much worse (i have panic attacks now, and never had one before using benzos)

so i think GABAergics are the way to go, if they're available where you are. go for the safest ones at first and see if they work for you

on the note of therapy, it's great for some people. personally i don't get anything out of talking or listening to someone else- whether my psychiatrist, a psychologist, or anyone. it's not like they know me better than i know myself. i study myself all day and generally feel dissociated and detached among other people.. i think cause my anxiety is so high around people now. it doesn't matter if it's my parents or someone else.. anyway i also have schiz, borderline personality and bipolar so that could be why

drugs are the only answer for some people. CBT is the only answer for some people. i think that sums it up. anyway, good luck op. let us know what works
 
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