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  • BDD Moderators: Keif’ Richards

Lorazepam information

MercedesBenzo

Greenlighter
Joined
Feb 21, 2013
Messages
5
So, a friend of mine came into some Lorazepam( I will use LZ from here on out) a while ago. Like, a lot of it, and she was curious as to how much one would have to take to get high( not "high", she understands the type of induced feeling created, but the amount necessary for recreational (ab)use. She also would like to know any potentiators, inhibitors to the effects of LZ, methods of lengthening/shortening effects, oral/nasal bioavailability, rather or not a crash is present at the end, and drugs that it can be combined with. She was also curious as to smokability and dissolvability. Her main question on LZ( And she has looked ALL over the internet, I assure you...) was really just a desire to know how much she would need to take to get high, and where the danger zone started. Thanks in advance.
 
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Start with 1mg, maybe even 0.5mg if you don't have much experience with benzos, then work your way up 0.5mg at a time. Best way to take it is oral or sublingual (under tongue), don't snort or smoke it, it's pointless and will waste it. Benzos are pretty safe in that it's difficult to OD on them alone, but try to keep it below 3-4mg or so.
 
Here's my opinion, which if you did a search for, you probably would have seen multiple times. Lorazepam isn't fun, you don't take it to get high, it's a tool. It dulls the effects of other drugs, you can't mix it with any other CNS depressants (No opiates, no dxm, no alcohol), you can't shorten or lengthen the effects from a single dose, it isn't water soluble so nasal is out of the question, there is no crash because there is no high. The more you take, the more tired and sedated you become, at no point will you feel an outstanding sensation of being high. 1-2mg is a good starting recreational dose. Trade name - Ativan - and it pretty much sucks. Just get some beer or pot instead.
 
Take it sublingually. If you don't have any benzo tolerance try maybe 2mg to start, might be enough really. You don't want to take too many benzos at a time because you might just black out. If it doesn't feel like enough you can always dose up slowly and gradually.
There isn't any sort of crash or comedown. Do NOT combine it with other CNS depressants such as alcohol or opiates as this will greatly increase the risk of overdose.

It's rare to overdose on benzos alone, but taking too many can bring you into dangerous situations where you're nto really in control of yourself, can get taken advantage of, or might lose your good judgement and take other CNS depressants, thus putting yourself at OD risk.
I'd start with 2mg and work your way up if it's not enough :)
 
Thanks to everyone, the information is GREATLY appreciated, I assure you. Any idea as to dissolvability or potentiators?
 
Idk what you mean about dissolvability. Ativan has a high oral BA, take it on an empty stomach. Don't snort it don't inject it, don't smoke it. Sublingual administration will cause a quicker onset of effects, and whatever isn't absorbed under your tongue will be swallowed anyways.

Start with 1mg as 2mg sounds a bit much. Start slow and remember you can always add more an work your way up, but you can't remove the drugs you have taken or lessen the effects if shit hits the fan. Start with 1mg on an empty stomach, don't expect much though just some sedation, relaxation, and attenuation of anxiety.

Remember that benzo withdrawal can be fatal. Don't take lorazepam everyday or you will develop a physical dependence to it and experience withdrawals upon cessation.

Unfortunately, lorazepam isn't metabolized via cytochrome 450 hepatic enzymes; rather lorazepam is oxidized through O-conjugation, so there is no way to increase the duration of effects like you can with grapefruit juice or tagamet to potentiate Xanax, valium, ect...most benzos can be pontentiated by inhibiting hepatic enzymes because most benzodiazepines are metabolizes by the cytochrome 450 family, but some are oxidized like oxazepam or lorazepam so there is no way to potentiate.
 
Hi MercedesBenzo, welcome to Bluelight :)

If it's you that you're talking about we prefer you just say that instead of saying it's a friend.

One thing you should know about BDD is that we are a harm reduction forum first and foremost, so we aren't really here to help you get as high as possible or more effectively abuse drugs, but to do so more safely. So a reminder to people who reply to consider that in their responses. But we can discuss normal recreational starting doses, side effects, risks, etc.

The main thing you should know about lorazepam is that it is addictive and if you take it too often you will get physically dependent and experience withdrawal symptoms when you don't take it, which can be severe and dangerous, so please be extremely careful and restrain yourself from using this drug too frequently.

As to your questions:

Safe recreational dose: Doses are going to vary from person to person, if you are not experienced with benzos I would start with 1 mg and see how it affects you. If you take too much you will pass out or black out. You would have to take a LOT for it to be dangerous to your life UNLESS you are taking it close to other drugs, it can be deadly if taken too close to opioids for example. Most fatal ODs are from combining it with opioids or alcohol.

Potentiators or inhibitors: I'm not really aware of any safe potentiators and there is no good reason to potentiate it, it's plenty strong on its own and you said you have a lot of it. Smoking cigarettes decreases the effects a bit, and stimulating drugs like caffeine will mask the effects somewhat. There are a couple of drugs that can decrease or increase its metabolism so let me know if you're on any other drugs.

Oral vs nasal bioavailability: The sources I have state oral bioavailability at ~85%-98% (the latter being on an empty stomach) and nasal at ~77% (and it's probably lower than that for pills intended for oral use). I would not snort it. If you want it to kick in faster you can put it under your tongue, which is listed at having a bioavailability of ~95% (for the regular oral pills when used sublingually).

Whether or not a crash is present at the end: There isn't really a "crash", since it's a sedating/relaxing drug, but you may feel groggy or experience rebound anxiety.

Drugs that it can be combined with: That is too vague, did you have any specific drugs in mind? We're not here to suggest drug combinations. I would say it's safe to combine in with cannabis. It is not safe to combine it with CNS depressant drugs, as mentioned above. It is not really worth it to combine it with stimulant drugs unless you are using it specifically to help ease the comedown from the stimulant.

Smokability and dissolvability: Don't try to smoke it. And it isn't soluble in water.
 
That was an exceptional response that hit every point I was looking for exactly on the head, and I appreciate the tips. I am, however, actually talking about a friend. o.o Still, I appreciate the information a lot as I dabble here and there and am likely to try some. I will inform her especially of the withdrawal symptoms possible fatality and the quick inset of physical dependance but state in earnest my applause for the great array of information gathered on said substance. Applaudable to say the least.
 
^Glad to be of help :). Sorry I assumed it was you - people often think they have to use tactics like "my friend" or "someone who isn't me" because those things are encouraged on certain other drug sites. Glad you are looking out for your friend and please let us know if she has any questions or if she is on any medications and needs to know if they have any interactions with lorazepam.
 
I know exactly what you mean. And yes, she takes Adderall for her ADHD and enjoys some occasional cannabliss. In the event that I ever tried it, I question what Ritalin might do to it's effects? My understanding is that Because both amphetamine and methylphenidate are stims, they would decrease the effects a little, which is to be expected when combine a CNSS with a CNSD. :)
 
If you take Adderall or Ritalin with lorazepam the stimulant will mask some of the effects of the lorazepam and the lorazepam will mask some of the effects of the stimulant. You won't feel either drug as much. Lorazepam can be useful to decrease some of the side effects of the stimulant, for example anxiety and insomnia. If you plan to combine these drugs I would just take the lorazepam when the stimulant is wearing off to help with any anxiety and insomnia.
 
I prefer low doses of benzos with amphetamines. I suggest for your friend to take 0.5mg and normal dose of addy in the morning, and when she starts to crash or it is night time, take an additional 0.5-1mg lorazepam and smoke weed. Thesemedications synergizes , but there is no cross-potentiation . Synergy is different from potentiation; amps, low dose benzo, and marihuana synergizes quite well in my experience and opinion.
 
Yeah, stimulants usually overpower the sedation of benzos, but benzos overpower the peripheral effects of stimulants. In my opinion, that's a great mix, but potential for addiction is strong.
 
Here's my opinion, which if you did a search for, you probably would have seen multiple times. Lorazepam isn't fun, you don't take it to get high, it's a tool. It dulls the effects of other drugs, you can't mix it with any other CNS depressants (No opiates, no dxm, no alcohol), you can't shorten or lengthen the effects from a single dose, it isn't water soluble so nasal is out of the question, there is no crash because there is no high. The more you take, the more tired and sedated you become, at no point will you feel an outstanding sensation of being high. 1-2mg is a good starting recreational dose. Trade name - Ativan - and it pretty much sucks. Just get some beer or pot instead.

Actually this is a rare case of a benzo that IS soluble in water. (Source)

None the less you gain nothing by these ROAs and they are much more dangerous. Stick to oral or sublingual as stated above.
 
Point taken. I was just pointing out that its solubility in water is a large deal greater than other benzos. Truly though, it's fairly irrelevant either way as the oral ROA works just fine.
 
I've definitely had doses at 10mg with lorazepam, I wouldn't recommend even a user with a high tolerance to ever go that high. But if you do, do not, whatsoever, take anything else that can cause Respiratory depression!

But honestly, my favorite rec. dose would have to be 3.5-5mg. But again, I'd recommend 1.5mg-2mg. And with benzos it's never really a 'high'. I'd say, shoot for contentment. I know there have been times where I've almost teared up from just pure relief.

But if it's a first time and you're planning on going out and about, I'd say start with 0.5mg-1mg.
 
So, a friend of mine came into some Lorazepam( I will use LZ from here on out) a while ago. Like, a lot of it, and she was curious as to how much one would have to take to get high( not "high", she understands the type of induced feeling created, but the amount necessary for recreational (ab)use. She also would like to know any potentiators, inhibitors to the effects of LZ, methods of lengthening/shortening effects, oral/nasal bioavailability, rather or not a crash is present at the end, and drugs that it can be combined with. She was also curious as to smokability and dissolvability. Her main question on LZ( And she has looked ALL over the internet, I assure you...) was really just a desire to know how much she would need to take to get high, and where the danger zone started. Thanks in advance.
Recreationally the most useless drug I have ever used.
 
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