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Opioids Loperamide (Immodium) Megathread: We have now lost at least 2 of our own from Lope

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After discovering that loperimide can rid you of withdrawal and get you high I decided to try it. I read some claims in this thread and others that loperimide doesn't constipate you more than other opioids. WRONG. Here is a study claiming otherwise:

http://www.ncbi.nlm.nih.gov/pubmed/6502516

After getting on loperimide at doses of 100 milligrams a day for several months I woke one night vomitting acid and blood feeling like I had a puncture in my stomach as a tire was punctured. Intense hiccups, bloating and stomach pain. I picked my ass up and rushed the emergency room. I told them I had taken loperimide and they were not convinced, in fact humoured. All it took was one projectile for them to take it seriously. They drew blood, gave me and abdominal/spinal x-ray, and an ultrasound. They found intestinal blockage, megacolon, initial signs of kidney failure, and sepsis. They surgically removed the fecal matter in my intestines, evacuated my colon, gave me lactulose to sooth my intestines and help relieve constipation, put me on two anti-biotics, and a PPI. They kept me for 2 days and released me. I left with a great feeling of happiness thinking "oh well at least I escaped withdrawal." WRONG. The next day it started kicking in, shitting, pissing, and puking at the same time. So I fixed up and squirted up my arm. Nothing. Not a single bit of relief. In the end, all I was left with was a huge tolerance to heroin which I don't know when it will reverse, constipation, diarrhea, vomiting, a fucked up digestive system, and disgusting withdrawal symptoms. It's been two weeks now and I'm still feeling them hard on. Only one drug made me suffer worst withdrawal and that's pregabalin, that's for another time though, for now: Word to the wise, use as intended and don't believe all the bullshit people are willing to convince themselves to justify a dirty, dirty, habit. There's no easy escape. I'm just so disappointed I was fooled yet again.

I would never use that much for that long, I don't even use that high of a dose, and definitely not daily. That really sucks that that happened to you. I used it last night and the body high was so intense that I did not sleep at all despite being extremely drowsy from it. I never get constipated for more than 2 days.
 
I would never use that much for that long, I don't even use that high of a dose, and definitely not daily. That really sucks that that happened to you. I used it last night and the body high was so intense that I did not sleep at all despite being extremely drowsy from it. I never get constipated for more than 2 days.

Good for you. I guess you fall into the use as intended group. However, you must have not read through this thread because there are many people using the same dose, slightly less, or much higher than me for much longer periods than me. I'll tell you something else, I didn't think I was constipated because I wasn't eating a lot and taking small shits. I guess my body was so numb that I wasn't alerted to the chaos going on inside me until the medication started to wear off. One thing none of you can say now is you haven't been warned.
 
I am sick of people bashing this. The first time I did it, it was so powerful it made me scared for a little while. It works. I have a feeling that most of the people who bash this have only read the forums and not tried it. I am on 72 mg= 36 pills right now + cimetidine + quinine.

I didn't read your earlier post Kratom bomb, I stand corrected, your also a heavy user. Be ignorant if you want, what do I care. I said my piece.
 
if you abuse loperamide, you need something to clear your bowels out. does a fecal tumor sound fun? having a fecal tumor removed surgically?

use common sense and make sure you take a shit.

epsom salt / magnesium sulfate.
 
Common sense and listening to your body goes a long way. Loperamide can be a godsend. Just dont go apeshit crazy on it and you won't end up in the hospital. It's a withdrawal aid, not a cheap high, nor an ultra high dose maintenance drug. :face palm:
 
I only do it once in awhile. I never do it a second time until after I defecate. I do understand the risk, and I have been warned. I may stop entirely. I always make sure I eat fibrous food, and maybe a laxative to be safe.
 
Good for you. I guess you fall into the use as intended group. However, you must have not read through this thread because there are many people using the same dose, slightly less, or much higher than me for much longer periods than me. I'll tell you something else, I didn't think I was constipated because I wasn't eating a lot and taking small shits. I guess my body was so numb that I wasn't alerted to the chaos going on inside me until the medication started to wear off. One thing none of you can say now is you haven't been warned.

yeah and you many people are taking these grossly huge amounts unnecessarily. you don't need anywhere near 100mg of lope to simply hold you reasonably well with even quite a large habit.

i have a high tolerance and get by fine on taking no more than 10-12mg/24hours, spread into 2 or 3 doses. you can shit as usual on these doses as well instead of continually being constipated from those ridiculous doses.

it does good to experience some of the pain of withdrawal to deter you from getting in that situation again and again and again. you'll develop a lope addiction taking that amount regularly as well; swapping one addiction for another.
 
yeah and you many people are taking these grossly huge amounts unnecessarily. you don't need anywhere near 100mg of lope to simply hold you reasonably well with even quite a large habit.

i have a high tolerance and get by fine on taking no more than 10-12mg/24hours, spread into 2 or 3 doses. you can shit as usual on these doses as well instead of continually being constipated from those ridiculous doses.

it does good to experience some of the pain of withdrawal to deter you from getting in that situation again and again and again. you'll develop a lope addiction taking that amount regularly as well; swapping one addiction for another.
No but I don't do it even close to regularly. I do it for the unique buzz, not for w/d's. I haven't been using opiates very much lately, when I did do it allot, it was never to the point where I could really call myself an addict, although, I have had w/d's before. I think loperamide works well with me also because I have chronic diarrhea. I think I honestly need a prescription for lomotil, I would not abuse it though, it is mixed with atropine so it will raise your heart rate, which I think is kind of sinister. I have never taken anything heavier than hydromorphone, or oxycodone. I will never do heroin because I think I would like it too much, and I'm terrified of needles. lol
 
I didn't read your earlier post Kratom bomb, I stand corrected, your also a heavy user. Be ignorant if you want, what do I care. I said my piece.

What purpose does the attitude you're injecting into this serve? You put forth a very unfortunate anecdotal report of what happened to you with the drug. I'm very sorry that happened and, like anything else, it is cause to be careful.

However, everyone reacts differently to all drugs. No two people usually are the same. Your experience, however scary, does not guarantee the same shall happen to the next person. It doesn't work that way. Secondly, no two ways about it, your consumption was excessive.
 
Is there realistically anything loperamide could do for me as a moderate to heavy H (IV user)? It just seems like it would be trying to put out a fire with a drop of water. I have no Cimetidine, H+ inhibitors and don't want them - I have no desire to turn my body into a chemistry lab. If I do it, I just want to withdraw as quickly and painlessly as possible, using ONLY loperamide. Is this possible? What sort of dosages would be required, and most importantly will it help with withdrawal symptoms OTHER than diarrhea (particularly sweating, god I hate that,RLS,vomiting,depression,lethargy). Maybe Clonidine + Loperamide would be a good combo. Any advice? I really don't want to go on bupe unless I have to. I wanna just kick and forget I ever did it if that's possible.
 
What purpose does the attitude you're injecting into this serve? You put forth a very unfortunate anecdotal report of what happened to you with the drug. I'm very sorry that happened and, like anything else, it is cause to be careful.

However, everyone reacts differently to all drugs. No two people usually are the same. Your experience, however scary, does not guarantee the same shall happen to the next person. It doesn't work that way. Secondly, no two ways about it, your consumption was excessive.

My post was addressed to those who are not using it therapeutically. Such as my self, and about 100 other people in this thread, and 100 other more. I was ignorant as well because I chose to ignore the healthy advise about loperamide use. My consumption was less than two months of use started at 20 milligrams and titrated to 100. Others have been using it for years in much larger quantities and there's no doubt many more will. I was merely trying to put to bed the myth that loperimide doesn't constipate you more than other opioids which it most certainly does.

On an additional note, much like another user kev90 mentioned, ever since I've stopped this drug everything smells so putrid and I have no idea why. I'd love for someone to chime in.
 
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I was VERY scared to start this immodium thing. I even cried as I was so scared. Took the immodium at 6 pm yesterday . I took 20. At 9 I took a Xanax and crashed out. Woke up about 430 am, took 9 more. Went back to bed. Woke up at 930 am. Slept amazing. Just now took 10 more.( so I'd say every 8-9 hours) in the middle of packing and doing great. Felt a heavy feeling so hubby made me a maca root( read about it) and gave me my energy back. It's been almost 24 hours since I've had a 20 mg Norco. ( 2 10-325) I'm SOOOOOOhappy as I was VERY skeptical.
 
Ps... I'm only taking this for about 3-4 days tops. No withdrawls at all. Feel great. Not high though just normal. I was on 120-150 mg a day for 3 years of 10-325( 2 every 2-3 hours)
 
well be prepared, the withdrawal is still lingering, just waiting for the loperamide to start clearing out...

also note that loperamide withdrawal can be much worse than hyrocodone withdrawal
 
^ as long as you taper it down, it shouldn't be that bad. People make the mistake of thinking if they switch to moderate-high doses of loperamide for the usual duration on their withdrawal, after that they'll be fine. It's just replacing the opioid(s) that you're used to with another one.

If people use the lowest dose they can and taper 1-2mg/day, they can escape a substantial part of the withdrawal. The biggest mistake people make though is thinking even this is enough. Getting past the physical aspects will not keep people from wanting the drugs, you have to address that and change yourself/your life or you'll just be miserable with PAWS or whatever lead you to use until you pick up the drugs again or make some changes.
 
^ as long as you taper it down, it shouldn't be that bad. People make the mistake of thinking if they switch to moderate-high doses of loperamide for the usual duration on their withdrawal, after that they'll be fine. It's just replacing the opioid(s) that you're used to with another one.

If people use the lowest dose they can and taper 1-2mg/day, they can escape a substantial part of the withdrawal. The biggest mistake people make though is thinking even this is enough. Getting past the physical aspects will not keep people from wanting the drugs, you have to address that and change yourself/your life or you'll just be miserable with PAWS or whatever lead you to use until you pick up the drugs again or make some changes.

yes but i was refering to a particular users "3 day max" on loperamide. that, after a multiple year opioid habit, will not provide a rainbow colored, fluffly landing zone. in fact, ive seen quite a few people make worse of their situation via loperamide.

though i totally agree with you when loperamide is used on a rock solid taper... a very smooth landing indeed. i think one of the greatest aspects of this method is that the psychological craving is not nearly as bad with loperamide than probably other psychoactive narcotic, so it helps tremendously with the final rounds. i think for most people, this is truly the last, and sometimes overlooked, hump; breaking 'thru' the worst of the psychological mess you are left in.
 
When I said 3 days I meant at higher doses. After that I'm going down til I'm done. I started off at 20 , then 10 now 8 & I'm
Good. Plus at night take 1 mg Xanax for sleep. What does any one suggest I take to poo? I am
SO proud of myself. Today at 3 was 48 hours since my last 2 norcos:))))) I'm super proud and I will NEVER TAKE THESE AGAIN, even when my endo is bad.
 
i've found Coloxyl (stool softener which is docusate sodium, 120mg) is a great one to help out one or two days a week if you're having trouble getting it out.

if you're constantly constipated for days on end on a regular basis it gets extremely unhealthy for you. so you need to change up if thats the case; whether it be lowering your dose, adjusting your diet, exercising, etc. just making sure you're adeuately hydrated makes for an easier (on the ass) shit. it doesn't leave it coming out in one huge ball, dried up, tearing and shredding your ass apart.
 
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