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Opioids Loperamide (Immodium) Megathread: We have now lost at least 2 of our own from Lope

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So back on this stuff after pods were becoming too prohibitive. Four figures a month. Oh yes it is dirty feeling and much more sedating then good ol pod tea. This is the only stuff this cheap that controls the cravings -- unless you somehow get subs with copay or through one of those pharmaceutical financial subsidy programs.

Upon further reading, there's nothing really conclusive about loperamide and Parkinson's. That one study didn't even really make that conclusion, only compared a Parkinon's causing metabolite to one in Loperamide.

Unlike other opis, this stuff gives me bad bad narcolepsy countered only with a nice NDRI. I see the Wikipedia article is now more pointed at mentioning its ability to cross BBB at high doses. Will be interesting to watch future developments when the feds find out about its increasing prevalence for recreation and dependency (and addiction -- in my case at least) maintenance.
 
wow im so glad i got off loperamide. that was the worst problem. made me want to rip out my intestines and jump out a glass window.

high doses caused tremors. also a feeling of unpleasantness and/or worthlessness. god bless kratom and bupe. FUCK loperamide.

ever read about the man who took 192x2mg loperamide a day for about 6-9 months then went cold turkey? he said CT methadone wd wasn't nearly as bad. i hate loperamide, hate hate hate. i just think off all that SHIT just backing up in my intestines. ive heard of paralytic ilius with the stuff. then you have to slam some MgSO4x7H2O.

shit backs up, shoot it out with epsom, shit backs up, shoot it out with epsom, shit backs up, shoot it out with epsom...
 
Sorry to perpetuate this particular thread and beat a dead horse by posting on this thread(if it is actually upsetting anyone) but I just wanted to share an anecdote that made me want to read all of the loperamide-related posts on here out of curiousity just to see if what a former acquaintance told me was even possible-that a person could indeed get "high" using Immodium. I socialized with him in 2008 regularly and he was convinced that based on his own first-hand experience, that beyond any shadow of a doubt, it was possible to get a significant opioid/opiate buzz/high by (DO NOT ATTEMPT THIS!) cooking up loperamide along with quinine in a spoon and slamming it I.V.(NEVER INJECT ANY DRUG!). I don't know the dosages of either drug used or if there was more to the process than simply this. Furthermore, I have no idea what sort of serious adverse effects that doing this could cause, even if it did work. I wouldn't want to find out the hard way. With that said, loperamide has been a life-saver for me on more opiate-detox occasions than I can count. I've taken way more than the recommended dosage multiple times during detoxes just to get my bowel movements down to semi-solid and to make my bowel movements occur less than 5 times in a day.(I was a big time opiate/opioid abuser, and I am not proud of it.) I never personally experienced adverse effects from taking large dosages of loperamide, but that isn't to say that there aren't any.
 
Loperamide

I took 18 2mg lope tablets with grapefruit juice and tonic water. I am a very opiate tolerant individual. It all started from a car accident where. Was run over by an f350. I was prescribed 75microgram/hr fentanyl patches and 1Omg norco every 4 hours and 2 30mg oxys a day. After being cut off off my pain meds I started with H. It's been about a year since iv been on that. I tried the lope after being sick for 24 hours after my last dose. The lope did help with the w/d but I was not high at all. I'll def be using this method to try and kick. A lot of info on Here really helped me out.
 
36mg loperamide is not enough to get you high, especially if you're not opioid naive. Try 100mg and I guarantee you will get high. I'm tolerance to bupe, thanks to taking 8mg ever day, and even 12hrs after my last dose of bupe I can get legitimately high after taking 180-220mg. Fun stuff.

Good luck Wax!!! I'm glad to see taking an unbigoted interest in my little lope baby ;)
 
Sorry to perpetuate this particular thread and beat a dead horse by posting on this thread(if it is actually upsetting anyone) but I just wanted to share an anecdote that made me want to read all of the loperamide-related posts on here out of curiousity just to see if what a former acquaintance told me was even possible-that a person could indeed get "high" using Immodium. I socialized with him in 2008 regularly and he was convinced that based on his own first-hand experience, that beyond any shadow of a doubt, it was possible to get a significant opioid/opiate buzz/high by (DO NOT ATTEMPT THIS!) cooking up loperamide along with quinine in a spoon and slamming it I.V.(NEVER INJECT ANY DRUG!). I don't know the dosages of either drug used or if there was more to the process than simply this. Furthermore, I have no idea what sort of serious adverse effects that doing this could cause, even if it did work. I wouldn't want to find out the hard way. With that said, loperamide has been a life-saver for me on more opiate-detox occasions than I can count. I've taken way more than the recommended dosage multiple times during detoxes just to get my bowel movements down to semi-solid and to make my bowel movements occur less than 5 times in a day.(I was a big time opiate/opioid abuser, and I am not proud of it.) I never personally experienced adverse effects from taking large dosages of loperamide, but that isn't to say that there aren't any.

Oh, yuck! Are you serious? I can't imagine IV Loperamide! I've never heard of this. I guess, then again, some people might be grossed out about the fact that I shoot my Suboxone..
 
Nope, I think banging lope is significantly more disgusting than shooting suboxone... But who am I to judge :\

Still, I can't imagine shooting that. I mean, given that it takes me 100-200mg to get a buzz, even if you shot 50mg, that's still a SHIT load of pill... baaaaad news, all bad, all bad...
 
36mg loperamide is not enough to get you high, especially if you're not opioid naive. Try 100mg and I guarantee you will get high. I'm tolerance to bupe, thanks to taking 8mg ever day, and even 12hrs after my last dose of bupe I can get legitimately high after taking 180-220mg. Fun stuff.

Good luck Wax!!! I'm glad to see taking an unbigoted interest in my little lope baby ;)

I think they are just using it to kick though, so they shouldn't be taking the high doses that you mentioned. The loperamide withdrawals are still bad, so it's best to just take enough to get by, and taper down from there. Using loperamide to get high is a bad idea since it has not been researched and studied in such high doses, and you still have to deal with the withdrawals. If I am going to have to deal with withdrawals, I would rather have them be from opiates that I really enjoy. Taking it to ease withdrawal symptoms is a different story, and I think that it's a great tool in that case.
 
Yea, overall I'd have to agree with you. I have taken lope 3-4 times to get high, and the drug worked very well with absolutely no noticeable side effects, at least short terms. That being said, absolutely, even doing once a week or two, I can't imagine how bad the w/d would be from a real habit. I imagine it would be at least as bad as methadone w/d. I just get sick of people saying you can't get high on it or making fun of people who use it. At the end of the day, an opioid is an opioid, even if it hasn't been studied or poses some theoretical/potential danger. The truth the matter is, even if it isn't the safest opioid out there, it will still get you high if you take enough.

Thanks for the thoughtful post TB
 
Yea I understand that it may get annoying to see people saying you can't get high from it when you have gotten high from it, but you have to keep in mind that this is a harm reduction website first.

As for the withdrawals from it, check out this thread.
 
So well, after so many posts, some people do believe that it CAN get you high, some other don't. The most of the folks says it works very well in the W/Ds. I have a question:Do you believe that it can potentiate opiates, (i'm on the fent patch, 100mcgr/h every 48hrs), and if it can, at what doses (and ROA..)? (i appreciate every answer, especially if someone has tried the fent/lope combination). I also take Elavil(amitryptilline) and Lyrica..Thank you very much, all of you mates..%)


MartinFn
 
^ That's a slippery slope. If you try to abuse a drug that is a great tool for helping with withdrawals, it will be a lot harder to use it for withdrawals later on. Some people actually report that loperamide takes away from the opiate high, and theorize that it may have a bloackade effect. I wouldn't pass that off as fact, but rather the experiences of some bluelighters that took loperamide with other opiates.

I wouldn't do it because it can attribute to a higher tolerance, without giving you a proper high. I have taken loperamide and then heroin later on, and it actually did seem like I got less of a high from the heroin, but it could have just been a weaker batch.
 
I agree with TB here, as I never found mixing lope and heroin or oxycodone or hydrocodone to be beneficial. HOWEVER I have heard that lope potentiates or increases (in a positive sense) the effects of kratom... so who knows? Seems like it's a kind of person thing, whether it adds anything or not, as the lope high itself is something people seem to either love or hate (kind of like tramadol's high).

[w00t w00t 700posts =D]
 
I have just joined this in hope for some help from people that have been there and can understand what I'm going through. I started taking oxycodone, oxycontin back in 2001. I decided to get help for this when I heard of Suboxone being a miracle drug in 2004. Well, up until about 7 days ago I was still taking 8mg of Subutex and decided I wanted to quit- it was now or never. I have been taking Loperamide to help with the withdrawals and it has helped a great deal, but now I'm worried about the withdrawal from that. How should I taper off of this medication? Thanks for any help...
 
I have been researching this loperamide thing on and off or a few months, when I am out of anything else anyway. Today I bit the bullet and bought a bottle of 72, or 76, either way, It was the $5 bottle you can get for wallmart.

I have been clean for a couple days and had a clear system to judge what effects it may have. I took 24 to begin with to get a feel, within an hour or so I had a sluggish opiated feeling, definitely something happening although my stomach felt some discomfort. Being the good druggie I am, I fell back on the old adage "If little does a little, a lot will do a lot". I took 24 more. An hour or two later the opiated feeling did increase, but my stomach discomfort grew exponentially.

It's now been 5 hours since I dosed last and I have to say there is a high and it does linger, however the stomach discomfort is just not worth it for me. The high itself is different, I would say it is like tramdol a bit (something I don't find pleasurable).

I realize that there are a number of variables in this case, ones own BBB permeability, chemistry and possible use of potentiators. However I would only recommend this only to those in mild or heavier withdrawl, I find minor withdrawl to be more pleasant than ingesting loperamide in any other manner than directed.
 
Out of curiosity, because I've heard it compared to tramadol and dextropropoxyohine in the past, is the buzz speedy? Or is it sort of heavy in a methadone like fashion?
 
Or is it sort of heavy in a methadone like fashion?
You nailed it, it's just like methadone to me anyway. A very very weak methadone crossed with tramadol.

I suppose at the 24 (48mg) level it was all right, but I had an intense "just a little bit more" thing going. Like I almost felt good. Once I was high though, it almost felt like dizzy/floaty feeling you have when you are sick.

I read earlier in this thread someone saying he thought it messed with there vision or he felt 'heavy' in his eyes. I read that after my experience, but I agree with this findings.

Given the large, varying reports I hear from this stuff though, I think the individuals chemistry and conditions make it love it or leave it. The only other opiate I came across like this was tramadol. I never have got an enjoyable buzz from the stuff and it just makes me feel...not right.I thought the positive reports were just young kids wanting to show off 'how high' they were at first. But after being around my friend who loved this stuff, I could tell he was genuinely high and having a good time.


*edit - I should have added, I felt neither speedy or sedated, just 'heavy' if I was setting. Walking around I felt normal but dizzy at times.
 
I have just joined this in hope for some help from people that have been there and can understand what I'm going through. I started taking oxycodone, oxycontin back in 2001. I decided to get help for this when I heard of Suboxone being a miracle drug in 2004. Well, up until about 7 days ago I was still taking 8mg of Subutex and decided I wanted to quit- it was now or never. I have been taking Loperamide to help with the withdrawals and it has helped a great deal, but now I'm worried about the withdrawal from that. How should I taper off of this medication? Thanks for any help...

It depends how much you're taking. How long have you been taking it exactly? And, of equal importance, how much have you been taking?
 
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