Loperamide after/with/before Bupe

[sm0kestack]

I am currently coming off a 5 day long heroin binge, and successfully inducted 1mg of bupe (2x .5mg IV'd with no PWD issues). I also have a whole bottle of 72 2mg loperamide tablets. I am still havung quite a bit of GI upset issues. Would just a normal dose to kill the GI issues be blocked out by the bupe and be rendered pointless? And if i were to try this out would taking more bupe as needed send me into PWD, or as i am thinking since i already successfully inductes bupe without PWD it wont matter? I feel OK, but my stomach is still fucked up. I am not looking to megadose the loperamide in attempt to get high or even ease WD, since the bupe is already doing that.

I just want to make sure that it isnt pointless taking the lope?

Thanks peepz.

 

[chelle216]

You should be fine and the loperamide should help, though you may need to take more than one tablet. The binding affinity of bupe is pretty tough, and a standard dose of loperamide won't break that, since the bupe isn't getting knocked off the receptor, continuing to take the bupe daily shouldn't present a problem.