The only information I could find was one report saying the mix did not synergize well, although many reports indicate that 2C-I with mushrooms is a great combo. More evidence that there is considerable qualitative differences between 4-AcO-DMT and mushrooms.
In the end my girlfriend and I chose to take 20 mg of 2C-I without anything else.
2C-I is the perfect festival drug. At 20 mg we both experienced amazing visuals, very "Alex Grey"-esque to be cliche with spirals and eyes forming throughout the sky, indicating universal awareness. The CEV's were beautiful. Very euphoric as well. And rather stimulating. Perfect for a festival.
At the same time we both kept our composure interacting with many friends and a few new aquaintenances.
Not nearly as deep as 2C-E, but much more manageable in a public setting.
My girlfriend is on SSRI's and she took her 30 mg daily dose of paxil earlier than usual just in case she forgot to bring them to the festival. We both experienced the same level of intensity at 20 mg, but her comeup was slower. She ended up peaking as my peak was tapering down, but other than that the SSRI's had no perceivable effect on the experience.
Since my girlfriend has been on an SSRI she can't feel the magic of MDMA (obviously), and she said that 2C-I provided a very similar euphoriant effect, most likely precipitated partly due to the brilliance of the visuals. She remarked that all of the stars looked like diamonds in the sky, and she understood what the Beatles were conveying.
My girlfriend takes paxil for depression and anxiety and she felt that 2C-I was the perfect psychedelic for being out in public. She finds psychedelics to be very therapeutic in helping her with anxiety and depression and has found usefulness in more heavy duty psychedelics such as LSD and 2C-E but after this experience she decided that due to her anxiety, 2C-I was the most appropriate psychedelic to do in public. She recently dropped LSD at a Tool concert and it was a little too intense
With 2C-I, she had complete relief from any signs of anxiety. We both felt great.
I brought 2 gels with 12 mg of 4-AcO-DMT, but we didn't feel any need for them. 20 mg of 2C-I was great at an outdoor festival. The Cat Empire and Arrested Development singing the Sly song "Everyday People" were the highlights. Overall very fun psychedlic experience without literally "weaving the fabric of reality in layers throughout your psyche revealing the true lattice nature of the universe" like LSD.
Sorry I can't add more knowledge about the mix, but 2C-I was pefect on its own for a festival and yes, as the above poster advised, less is more!
Simplest way to describe 2C-I.
Fun.