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  • BDD Moderators: Keif’ Richards

Looking for harm reduction info on a combo

BabyGurl3171

Bluelighter
Joined
May 25, 2010
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In my mind. The choices are many, the consequences
I'll list my tolerances and what I've taken so far. Then I'll list what I'd like to add. Just wanna know if it'd be ok or not.

Taken:
40 mg Ritalin swallowed whole (rx'd 60 mgs) took 20 at 10 am & 20 at 130 pm. (60 mg a day is the most I've taken.)

7 mgs alprazolam sublingual (tolerance 16-20 mgs with no black out; rx'd 6 mgs a day) took from about 2 pm til 5 pm.

Now 6 pm my time.

2 mgs klonopin sublingual (rx'd 4 mg a day; took about 2-3 pm) tolerance have taken 10 mg over 2-3 hrs before.

Now I'd like to add the following bc I'm sober af:
2 mg alprazolam sublingual

2 mg klonopin sublingual

10-15 mg hydrocodone (tolerance between 20-30 mg since I had quit so long)

20 mg Ritalin but this time ROA will be insufflation.

600 mg gabapentin (tolerance is crazy. Rx'd 1,800 a day but taken as much as 5-6 grams at a time.)

So, would all this be ok? I have ADHD so Rit is not an upper to me. But not quite a downer like benzos either.

I literally feel sober af n it sucks ass!! Especially after my past few weeks.

I looked up interactions n it only said gaba may mix with alprazolam n just make u more tired or dizzy. But of course it probably took median doses n not what I have or want to take.

Thanks for the help!!
 
It's not really "okay" in the sense that it's really not safe exactly for this reason. Tolerance to all those drugs rises really quick, you need to take more, and then you take too much. Mixing stims/depressants is never a good idea. Mixing 3 depressants is not a great idea. Will you be physically okay, probably, can't say for sure though. Pick 1 drug and use that, much safer.
 
I suggest, as previously stated, that you cut the benzodiazepine dosages. Maybe just pick one benzodiazepine or the other. Mixing them is quite pointless.

There is no dangerous interaction between most of the stated drugs. Gabapentin is often used in conjunction with benzodiazepines, and there is no interaction between gabapentin and methylphenidate, or benzodiazepines and methylphenidate. I've combined the three quite often myself.

Your biggest worry should be that you're mixing massive doses of benzodiazepines, gabapentin which potentiates them further, and opioids. Even though the hydrocodone dosage is low, the benzodiazepine and gabapentin dosages are quite high. There is no telling how your body will handle them.

If you do plan on going through with it, I would strongly urge you to just take perhaps 0.5 milligrams of clonazepam OR alprazolam and cut the gabapentin dosage in half. If you feel like you can handle it well, but you need more, add no more than another 0.5 milligrams of chosen benzodiazepine, and the other half of your gabapentin dosage.
 
Thanks everyone! I ended up just taking 1 mg alprazolam, 10 mg hydro & no gabapentin. Still didn't get what I was looking for so yeah, tolerance is a bitch n I'm giving it a break after today.

Today I fucked up, honestly bc I was so depressed I didn't care anymore. I took, but this is from 8 am til currently which is 7 pm, 12 mg alprazolam, 10 mg hydro, 60 mg Ritalin & finishing a second beer.

I really fuckin hate life ATM but that's a whole other post/forum.
 
Good choice on dropping the gabapentin. Usually the opioid trumps everything around it. Perhaps not in this case because what your body is craving is gabaergics.

My advice to you is to stay away from mixing gabapentin and benzodiazepines. If you do it continuously you won't be able to use benzodiazepines alone. It will effectively send you into benzodiazepine withdrawal whenever the gabapentin is absent.
 
Good choice on dropping the gabapentin. Usually the opioid trumps everything around it. Perhaps not in this case because what your body is craving is gabaergics.

My advice to you is to stay away from mixing gabapentin and benzodiazepines. If you do it continuously you won't be able to use benzodiazepines alone. It will effectively send you into benzodiazepine withdrawal whenever the gabapentin is absent.

I thought gabapentin (and lyrica) had no direct gaba activity? I'm a frequent lyrica and benzo user and aware of how much it "potentates" benzos. I posted a question a while back wondering about concurrent use of the two and I didn't get many responses but one member thought it would be just synergy and not actual potentiation.



I posted:
"Since I was/am potentiating my benzos with the lyrica would the amount of benzo that I may or may not be dependent on ( xanax for example) would it still be .5mg or would it be considered higher because of the pregabalin? Also would I be at a higher seizure risk if I was in benzo withdrawal because of combining the two?"
 
Thanks bazooos! My body def wants gaba's lol. I'll admit that any day of the week.

I'm gonna have to quit for awhile tho bc my tolerance is thru the roof n I have panic attacks so def need them to work! Although since starting ADHD treatment my panic has decreased dramatically!!

Snake Eyes, I'm not sure what the answer is to ur question. Sorry! But I'm sure someone more knowledgable will come along :)
 
I thought gabapentin (and lyrica) had no direct gaba activity? I'm a frequent lyrica and benzo user and aware of how much it "potentates" benzos. I posted a question a while back wondering about concurrent use of the two and I didn't get many responses but one member thought it would be just synergy and not actual potentiation.



I posted:
"Since I was/am potentiating my benzos with the lyrica would the amount of benzo that I may or may not be dependent on ( xanax for example) would it still be .5mg or would it be considered higher because of the pregabalin? Also would I be at a higher seizure risk if I was in benzo withdrawal because of combining the two?"

It doesn't. It's a calcium channel blocker but speaking anecdotetaly, many of the people who suffer heavy pregabalin withdrawals use other gabaergics concomitantly. Having said that, much is to be revealed about how gabapentinoids actually work, so it may very well be potentiation, and not synergy.
 
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