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Long acting Nitrous Oxide derivatives?

^ Yeah, I was pretty sure of that. Haven't really looked into it beyond first impressions.

No one who has actually tried tiletamine would accuse it of being better than ketamine. It's mechanical and dull with no euphoria. Big waste of time.
 
i felt compelled to resurrect this, as someone who has done lots and lots of nitrous oxide for a long time (every few months me and my friends buy a few thousand whipped cream chargers), i would love to find some kind of longer lasting alternative.
ive tried a whole bunch of uppers and downers, but i dont think anything compares to a moderate amount of real cocaine with lots of nitrous oxide, ive tried various benzos, ive tried natural opium, but nothing ive tried has been able to replicate that feeling of someone taking an orgasmic jackhammer to your brain
the closest i came was one night when i was on tramadol for a little while for pain, one night i couldnt sleep and took 4 of them, had this full on rush in my head, like my brain was doing frontflips really fast, like your brain is the spinning bit in the middle of an engine being spun around by explosions (allbeit a much smoother faster whirring than you get on deep nitrous experiences)
i think probably the second closest ive come to the feeling was severe sleep deprivation on lots of mdma for several days, when i got home and relaxed in my room i felt like my skin was buzzing and vibrating and my mind was all jiggly, vision was flickering, only i was still very stimulated... nitrous gives me more like a downy mongy dissociative stimulation, less focused and wired..



any suggestions? i think it seems like im just gonna have to smoke some dodgy methaqualone like they do in south africa

and ive done lots of K and pcp doesnt look like the kind of thing i would enjoy, i dont get anywhere near comparative effects from ketamine other than glitchy vision and lack of dexterity, i dont get the buzz on ketamine that others seem to speak of (and ketamine is RIFE in south east england)
 
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Someone13232 said:
i felt compelled to resurrect this, as someone who has done lots and lots of nitrous oxide for a long time (every few months me and my friends buy a few thousand whipped cream chargers), i would love to find some kind of longer lasting alternative.
ive tried a whole bunch of uppers and downers, but i dont think anything compares to a moderate amount of real cocaine with lots of nitrous oxide, ive tried various benzos, ive tried natural opium, but nothing ive tried has been able to replicate that feeling of someone taking an orgasmic jackhammer to your brain
the closest i came was one night when i was on tramadol for a little while for pain, one night i couldnt sleep and took 4 of them, had this full on rush in my head, like my brain was doing frontflips really fast, like your brain is the spinning bit in the middle of an engine being spun around by explosions (allbeit a much smoother faster whirring than you get on deep nitrous experiences)
i think probably the second closest ive come to the feeling was severe sleep deprivation on lots of mdma for several days, when i got home and relaxed in my room i felt like my skin was buzzing and vibrating and my mind was all jiggly, vision was flickering, only i was still very stimulated... nitrous gives me more like a downy mongy dissociative stimulation, less focused and wired..



any suggestions? i think it seems like im just gonna have to smoke some dodgy methaqualone like they do in south africa

and ive done lots of K and pcp doesnt look like the kind of thing i would enjoy, i dont get anywhere near comparative effects from ketamine other than glitchy vision and lack of dexterity, i dont get the buzz on ketamine that others seem to speak of (and ketamine is RIFE in south east england)
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I don't have a good answer to your question but I urge you to find a better source of N2O if you can. Those whipped cream canisters are coated with oily, resinous gunk. Some brands are better than others, but they all have that shit in them. If you have a solid container you can crack the canisters into do a little experiment. Crack a few into it (3-4 should do the trick), then after you let the gas out rub your finger along the inside of canister. Maybe use a glove, the stuff does not like to wash off.

Every time you crack one, some of that residue is expelled with the gas, and when you inhale the gas some of it makes it into your lungs. N2O intended for human consumption won't have that gunk in it, and will spare you some health problems down the road.


Back to your original question, there are probably other inhalants that will produce a similar but longer lasting high to NO, but all of those are going to be more dangerous that N2O itself (black residue notwithstanding).
 
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This doesn't really address your question as originally stated, but you're looking for something like nitrous, but without its brevity, right? I found pretty solid auditory flanging with pot + methoxetamine. . .maybe you'll have luck with pot + a dissociative that works well for you. I think other inhalants are going to be pretty short-acting too, and they're all horribly dangerous, diethyl ether and xenon excepted.

ebola
 
I just thought of something else, nitrous can last as long as you want, as long as you keep delivering it and you don't die from a lack of oxygen (the latter being a fairly important point). So if you wanted a never ending nitrous trip all you would need is a mask with a mixture of N2O and pure O2 flowing into it.

Obviously never do something like that without a sober friend to watch over you and you'd need to be damn sure you had the right ratio of O2/N2O flowing.
 
endotropic said:
I just thought of something else, nitrous can last as long as you want, as long as you keep delivering it and you don't die from a lack of oxygen (the latter being a fairly important point). So if you wanted a never ending nitrous trip all you would need is a mask with a mixture of N2O and pure O2 flowing into it.
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Nope, that's not possible, because there is a rapid tolerance with nitrous when administered continuously:

The analgesic effect of N2O gradually decreased and was absent in all eight volunteers within 150 min. Two volunteers regained consciousness at 77 and 91 min of exposure, whilst still breathing 60 and 80% N2O. These results show that tolerance to antinociceptive effects of N2O in man rapidly develops and that awareness may occur in some volunteers during prolonged exposure to N2O.
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http://www.ncbi.nlm.nih.gov/pubmed/4061009
 
It's fun every now and then, but catalyzed my friends psychosis. Besides that, the stories I've read about heavy nitrous addiction are pretty messed up, and it apparently has quite potent withdrawal symptoms.

My friend worked in a headshop (different one), and he said the most pathetic looking guy would come in every day to pick up a few packs of N20. Then didn't show up for awhile, then they found him mumbling shit and laying in the parking lot.


And I find every other dissociative qualitatively different in almost every way except the disassociation. None have that giddy feeling, dextromethorphan and PCP analogues anyway, and the short duration is actually kind of a benefit. It allows you to use no and then without being smashed. Call it the "businessman's depersonalization" ;)
 
A 'long-acting' version of Nitrous Oxide isn't readily possible to be honest.

The only thing I can think of that might come close to being like Nitrous is a combination of a dissociative (Ketamine being the best in this case. Due to its lack of monoaminergic reuptake inhibition) and a light dose of a downer and a light dose of an opioid.
 
sekio said:
Maybe someone could invent a nitrous oxide prodrug. Stabilised nitrous acid ester maybe.
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I thought nitrous acid esters liberate nitric oxide, not nitrous oxide... Or am I just retarded and sleep deprived?
 
endotropic said:
I don't have a good answer to your question but I urge you to find a better source of N2O if you can. Those whipped cream canisters are coated with oily, resinous gunk. Some brands are better than others, but they all have that shit in them. If you have a solid container you can crack the canisters into do a little experiment. Crack a few into it (3-4 should do the trick), then after you let the gas out rub your finger along the inside of canister. Maybe use a glove, the stuff does not like to wash off.

Every time you crack one, some of that residue is expelled with the gas, and when you inhale the gas some of it makes it into your lungs. N2O intended for human consumption won't have that gunk in it, and will spare you some health problems down the road.


Back to your original question, there are probably other inhalants that will produce a similar but longer lasting high to NO, but all of those are going to be more dangerous that N2O itself (black residue notwithstanding).
Click to expand...

Is it possible to let that oil settle? Like after cracking it in a balloon, just waiting a few minutes or so, wouldnt the oil resolidify and settle to the bottom of the balloon?
Or what about, like you said, using a canister? Would that help reduce it atleast?
Im sure human consumption N20 would be great.

ebola? said:
This doesn't really address your question as originally stated, but you're looking for something like nitrous, but without its brevity, right? I found pretty solid auditory flanging with pot + methoxetamine. . .maybe you'll have luck with pot + a dissociative that works well for you. I think other inhalants are going to be pretty short-acting too, and they're all horribly dangerous, diethyl ether and xenon excepted.

ebola
Click to expand...

MXE is the best. ESPECIALLY with bud. My god, do I miss it :/



endotropic said:
I just thought of something else, nitrous can last as long as you want, as long as you keep delivering it and you don't die from a lack of oxygen (the latter being a fairly important point). So if you wanted a never ending nitrous trip all you would need is a mask with a mixture of N2O and pure O2 flowing into it.

Obviously never do something like that without a sober friend to watch over you and you'd need to be damn sure you had the right ratio of O2/N2O flowing.
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And, THIS ^ that is definitely the best solution, like a dentist/doctor setup. Albeit, you DO have to be very, very careful.
And Im unsure how some could do this without the proper machines.

Ive always wanted to be able to make a N20/oxygen mixture I can continuously breath in for effects of nitrous lasting longer than 30 seconds. Like a 30 minute nitrous oxide buzz :D

Anyway, I apologize for quoting three times!
 
RoboRobot said:
Is it possible to let that oil settle? Like after cracking it in a balloon, just waiting a few minutes or so, wouldnt the oil resolidify and settle to the bottom of the balloon?
Or what about, like you said, using a canister? Would that help reduce it atleast?
Im sure human consumption N20 would be great.
Click to expand...

I really don't know, but you can find out yourself. Crack into your balloon or canister, let it sit as long as you think will help, then expel into a fresh balloon. Wipe your finger along the inside, then compare with a fresh one. You might have to do a few per balloon to notice a difference.
 
Get a friend to keep loading you balloons, that's what we did and we could make NO2 last up to about 10 minutes. We wasted a fuckload of whippets though!
 
Nitrous oxide is pretty chemically inert, I bet you could build a gas recycler with some cartridges packed with quicklime to suck out carbon dioxide from exhaled N2O.
 
Methoxyflurane - very potent so you need proper mixer. It's got the lowest MAC number (is the most potent) of any inhalational anaesthetic. Used in sub-anaesthetic doses by emergency crews in Australia. The MAC number of nitrous oxide, to compare, is 120. I will let you read up on what MAC means if it interests you. I had a friend who was badly burnt 60 miles outside Perth and he got these:

penthrox-single-combo-methoxyflurane-inhaler_MDI-ME-MS245_exlarge.jpg
 
clubcard said:
Methoxyflurane - very potent so you need proper mixer. It's got the lowest MAC number (is the most potent) of any inhalational anaesthetic. Used in sub-anaesthetic doses by emergency crews in Australia. The MAC number of nitrous oxide, to compare, is 120. I will let you read up on what MAC means if it interests you. I had a friend who was badly burnt 60 miles outside Perth and he got these:

penthrox-single-combo-methoxyflurane-inhaler_MDI-ME-MS245_exlarge.jpg
Click to expand...


It is defined as the concentration of the vapour in the lungs that is needed to prevent movement (motor response) in 50% of subjects in response to surgical (pain) stimulus.

It says nitrous is 104, "The MAC is the concentration of the vapour (measured as a percentage at 1 atmosphere," How do you get a number above 100%, isn't that the max concentration?
 
lolwhatzdrugs said:
It is defined as the concentration of the vapour in the lungs that is needed to prevent movement (motor response) in 50% of subjects in response to surgical (pain) stimulus.

It says nitrous is 104, "The MAC is the concentration of the vapour (measured as a percentage at 1 atmosphere," How do you get a number above 100%, isn't that the max concentration?
Click to expand...

That means you can't get truly effective anesthesia with nitrous alone in most people.
 
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