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Lithium question

ColdNorth

ColdNorth

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Hello =)

I was redirected here after asking about this in the ecstacy forum.

I'm on 600mg lithium carbonate and 1.2mg buprenorphine daily. Searching for info on interactions revealed quite fast it's not a great idea to mix lithium and MDMA. To explain a little background I quit most drugs about a year ago after 3 consecutive mania-like episodes which escalated to full-blown psychosis with no memory or control of events.

I have bipo type 1 going on 15 years and the lithium keeps it at bay. Psychedelics, weed and opiates don't cause any problems. Alcohol, amphetamine and benzos all do and I've lost interest in all of them.

My question is how long after stopping lithium until it's at safe enough levels to take MDMA and also how long after MDMA until returning to lithium? I assume the buprenorphine is safe with MDMA but correct me if I'm wrong.

I'm only concerned with the physiological risk (interactions).

Thank you in advance.
 
To clarify, by amphetamine I meant speed, methamphetamine? English is not my native language and I mess up the terms. It's referred to as just amphetamine where I live, probably mistakenly.

Other members of that family that I've tried haven't had nasty effects, like 2c-anything. Only that stay awake-stuff. But good point, must go easy at first and see what happens. Still, I'd like to know how fast lithium levels drop and what possible interactions would one be risking?
 
If your on lithium don't go off it just to take MDMA. I'm bipolar as well man and although i don't take lithium i know how much of a disaster going off your meds can be. Taking MDMA might also set off a bad manic episode and so will methamphetamine most likely.
 
paranoid android said:
If your on lithium don't go off it just to take MDMA. I'm bipolar as well man and although i don't take lithium i know how much of a disaster going off your meds can be. Taking MDMA might also set off a bad manic episode and so will methamphetamine most likely.
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I understand your concern but I really need to do something, being on bupre this long has made me not give a shit about anything and life is pretty boring with neither manias nor psychedelic experiences in it. It's so hard to score LSD here the only empathy booster I can think of is MDMA. It'll be a lot worse if I don't fix the boredom.
 
ColdNorth said:
paranoid android: Mind if I ask what you take for yours and how much does it let you..have fun? =)
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I take lamictal, bupropion, clonazepam and if i need to take it risperidone or if it's a emergency olanzapine.

I can have fun of it i just have to skip the wellbutrin and if i'm on them the anti-psychotics. Lamotrigine does not seem to affect any rec drugs Ive taken. This includes dextroamphetamine, cocaine, LSD, psilocybin, ketamine, DXM, cannabis and just about every opiate you can get your hands on.
 
I had never heard of lamotrigine but 30 years newer, no blood monitoring and less side effects sound pretty good. Not to mention improved recreational options. Gotta talk to the doctor and see if that would work, thank you =)
 
Because lithium's thereapeutically relevant mechanism of action remains unknown, and because many presentations of bipolar disorder themselves can interact with drugs, interactions with lithium are unpredictable.

ebola
 
Ive been thinking of going on lithium to control the mania aspect of my bipolar so i don't have to take anti-psychotics which under my currant insurance would be either risperidone or seroquel. The olanzapine which works much better and as soon as i take it is not covered and as expensive as hell. The risperidone has alot of side effects at higher doses (2mg's+) and with seroquel it takes about 300-400mg's for it to work for me on mania and at that dose my mouth is so dry it can be hard to even swallow. Kinda like super diphenhydramine :p

The only thing stopping me from taking lithium and doing the lamictal/lithium combo which is supposed to be great is the blood tests which would be a pain in the ass.
 
I would highly suggest not taking MDMA if you have a bi-polar disorder. MDMA increases norepinephrine release and circulating cortisol levels, which may facilitate emotional engagement. It has also been shown to reduce levels of SERT's which sould make your disorder even more severe then it is. Best bet is to stay on the Li medication and avoid MDMA.
 
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