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Levo-amp levels seems too high in Adderall XR brand name vs Generic

Soap MacTavish

Soap MacTavish

Bluelighter
Joined
Jul 12, 2010
Messages
293
I hate to be such a cry baby but through circumstance I was forced to buy brand name Adderall XR at the pharmacy earlier this week.

2 things are tipping me off and seem wrong:

I have gone from my usual 30mg XR From Sandoz down to 25mg XR brand name Adderall. Being 5mg's less you would think it would consequently feel like 5mg's less. This is certainly not the case. What it feels like is nothing but an unpleasant roller coaster of Levoamphetamine and hardly any Dextroamphetamine.

It also feels like the time release mechanism on these is screwed or something because I am getting hit by a series of bomb boosts over a 4 hour period with the biggest bomb going off at 4 hours. It feels like these beads are garbage and they are clustering and not dissolving evenly. Why else would it be so bumpy like that. And I wouldn't mind the bumps if they were remotely enjoyable but this has got to be a higher percentage of L-amp, which is the stuff that gives you the physical speed nasties like too much caffeine if I understand correctly. Like thumping heart, angina pectoris, veins fuller to the point where they are tingling, jitters. All the stuff you dont want or need.

Any way you cut it my opinion of this brand name stuff is cut by the pharmacist speed freak and it's garbage. That asshole's probably shooting it up right now and fucking hookers.

I am getting nasty physical effects from this trash like pains in my aorta and running down the lateral side of my left arm which houses the basilic vein.

I know this is also from the vasoconstrictive elements of amps and could easily be vasospasms. I noticed the veins on my left arm are more pumped up than usual and are feeling prickly which is probably from high blood pressure due to that asshole pharmacist burning me. And I know this stuff is bunk cuz I took one of my other Sandoz 30's to test and my heart was ok.

I really don't feel like dying of a heart attack because some prick fuck asshole pharmacist wants to steal the dex-amp and shoot it into his dick and fuck hookers all night.

I have a couple questions:
#1 I have a beta blocker on hand, Propranolol (Inderal). If I take 40mg's or so will this have any bizarre interactions? I have done this before and did not seem to have any problems but earlier today I read that there is some serious consequence to taking a beta-blocker with cocaine. They didn't say what it was.

#2 Will Magnesium help with these shitty physical troubles?

And finally here is another very strange piece of this mysterious pill puzzle. For some reason unknown and still being withheld from me, My insurance company charges me a larger co-pay for the generic version than for the Brand Name expensive stuff. Never in my life have I heard of anything like this, it does not compute and does not add up.

Anyone have any insights into this madness?
 
Dude so lemme get this right, your pharmacist magically took the dextro isomer of your adderall and left you the levo isomer. If such an easy method for doing this is possible how come you don't do it and only use the d-amphetamine from your adderall. Lemme know how that goes. If your pharmacist was stealing pills 1 it would be opiates and 2 they'd go for the desoxyn if they were a tweeker.
 
The pharmacist thing was a joke really. Just threw it in there because I am really mystified as to how the same substance and ratio (supposedly) could feel so different. Last night I had both brands and the same thing happened, I wanted to double verify. I know this is anecdotal and not empirical but seriously, I just don't get it, if I would have started out on the brand name XR's, I never would have liked Adderall and I would have had a totally different opinion about it. It felt like speedy ritalin.

Who knows, if I was some pharmacist I might end up opening those capsules and swapping out the d-amp salts for ground down bleached nutmeg or caffeine pills myself. That dirty motherfucking scumbag pharmacist burned me dude and you think this is a joke? I'm physically and mentally dependent on Adderall and now I'm out 60 freaking pellets and I'm about to be withdrawling in a few days and that unethical speed freak addict with a dispensary license behind the counter posing as an upright helper of humanity won't take these bunk kitty-litter-stuffed tabs back and give me my money and prescription and say have a nice day.

I was hoping to stabilize on a slightly lower dose of 25mg twice daily because I have literally been on a ceaseless 2-month bender taking no less then 120mg daily up to 600mg daily at times. Last night was 240mg.

Something is up is all I'm sayin... Now I don't know what to do besides go CT. I was hoping to have some buffer and ramp down to 50mg daily and at least attempt to sustain there because without at least a basic script my ADD comes back and I turn back into the wretched scared retarded self-preserving self-hating masturbating cowardly thoughtless reckless impulsive lazy sloth of an excuse for a man.

Shit.
 
Soap MacTavish said:
I was hoping to stabilize on a slightly lower dose of 25mg twice daily because I have literally been on a ceaseless 2-month bender taking no less then 120mg daily up to 600mg daily at times. Last night was 240mg.
Click to expand...

Maybe that had more to do with your unpleasant effects than the composition of the pills.

Soap MacTavish said:
I turn back into the wretched scared retarded self-preserving self-hating masturbating cowardly thoughtless reckless impulsive lazy sloth of an excuse for a man.
Click to expand...

And maybe you should find another way to work all of this out that isn't just binging on amphetamines. Find someone who cares about you and talk to them about your problem before it becomes a bigger one.
 
Well, I've arrived on a new conclusion that the junkie pharmacist swapped out MDPV for my amp-salts. Whatever. I give up on this one. Hopefully this shit will hold my crash at bay till nex month...
 
LOL you should go down to the pharmacy and tell that bitch ass pharmacist whats up. OR you could have gone to a different pharmacy and bought the brand you like.
 
Well, I've arrived on a new conclusion that the junkie pharmacist swapped out MDPV for my amp-salts. Whatever. I give up on this one. Hopefully this shit will hold my crash at bay till nex month...
Click to expand...

This isn't particularly plausible. I'm sure this occurred to you, but you need to take far fewer stimulants, as things will start making MORE sense. :)

Also, tapers don't appear particularly useful with stimulant cessation, but YMMV.
 
agreed...kinda

I take 30mg daily for proper reasons, but I constantly bio-tune to bring out the more concious effects. Urinary and Stomach PH manipulation, dopamine tea, I aslo happen to be CYP2D6 enzyme deficiant, meaning tha exit route for the dextro is basically useless, thus my bio availibility tends to be elevated much longer than most the population. Down side of that of course is aphetamine tolerence builds much more quickly. That said, the last two refills of the 15xr have seemed week, late blooming and almost rollercoaster in subjective effects. More objective Peripherial effects such as pulse, and blood preasure increase are near non-exsistant without another cns like a cig or coffee on both these 'slow-amines' So i cant really use this for a comparison. At first a attributed this to indulgence of 30 IR generics in less theraputic doses the previous month, and even extensive MDMA over my adult life. For example the feeling 'constriction' when urinating, or the tingle in the scalp would were the only sign of any amp effects, for six hours. THen while playing a game a hightened interest appeared, lasted about an hour then yawns kicked in. THis pattern is repeatable in 3 outta 4 subs who tried the bunk ads. After 2nd month refill proved to be the same, an addition of 10's was given by doc. The 10's in theraputic dosing brought on all the subjective effects one expects from this stuff, though only for about 3 hours. THe final experiment was a mix and match. 10 was non effective whem injested with the 15. 1 of each, 1 hour apart, the 'verified' 10, then 1 hour AFTER onset of noticable effects the 15 was injested. Within 2 hours i was asleep. I woke up, with a slightly caffenated feeling 6 hours later. I guess i should say I'm not a bio-chemist no expert in anyway. all my knowledge is a combo of wiki and subjective observations of self and others. Now this may be a coincedence but we noticed the roughly 75/25 dextro/levo respecively aligned with the color of the beads. This color happen to inverse. Before I(and friends) noticed mostly light with about a 1/4 of xr pellets being a darker color (i'm colorblind) white and yellow i'm told. Now its flipped, my 2 theories are a bad lot, though with decent inspection standards it should be known by now. OR the formula is altered to aid in reducing tolerence and rotated in. Neither of these seem truly plausible, but I cant explain it any other way. In short I agree with you...for some reason, the name brands seem to have signifiganly increased the levo levels.
 
placebo or reward-wiring towards those pills might explain it.

pharma companies, including generic labs have to take thousands of random samples from every batch they make to test it, and if its uneven they have to scrap the batch basically. its a very tightly regulated market, and occasionally pills get screwed up, or people let things slip but they get caught.
 
@sackynut

Generics do not have to be bio-equivalent to brand name, there is a lot of leeway. A generic will contain the same amount of active ingredient(s), but the "inactives" differ. XR-meds will never be bio-equivalent to the original unless it is resold under license (like some oxycodone).
 
^ either im too high to put together what you just said, or you misunderstood what i said.
in the case of the latter:

what i meant was they have to test thousands of pills from every batch (which can be made in the Kg's or tonnes) for equal distribution of ACTIVE ingredients throughout the PILL. generic or brand name, it doesnt matter when it comes to that they have to follow the same FDA guidelines, theres not really much leeway in that department. which i believe is something different than what you were referring to.

so when it comes to levo amp and dex they have to be equally distributed throughout the generic to a certain extent (the same extend set for brand names) or they have to scrap the batch. Im sure there are some corrupt companies that find un-even pills and still ship out the batch, but from what Ive heard theres regulations in place to help prevent that.

inactive ingredients have huge leeway and yes, can differ. but i thought the OP was referring to higher levels of Lev [active] in his brand name.

correct me if im wrong or too high :D
 
I can't comment on the rest of this thread, other than that the OP ought to cool it on the stimulants, but OP is absolutely right about the Adderall XR time release being garbage. It's very inconsistent, and usually seems to release the drug faster than it should. (and IME, Adderall XR is nasty and jittery - seems more-so than the IR, despite that it's supposed to have the same ratio of d to l)
 
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