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Stimulants Kudzu root extract(diadzin) for DA and 5-HT neurotransmitter depleton from amp./stims

som3dankbudz

Greenlighter
Joined
Jan 27, 2011
Messages
44
The original use of this herb(diadzin) is as a Chinese herbal treatment for moderating the consumption of ethanol. Although, after reading up on this almost unheard of herb, from what I can find it acts as a mild ALDH-2 inhibtor. ALDH-2 happens to be a essential enzyme involved in metabolism of DA and 5-HT, but not on the level of an actual full MAO inhibitor. It's much more tolerated, and milder than a persription MAO inhibitor. Diadzin is comparable but has much less of the draw backs, an a actual nootropic effect. Anyway it supposidly tends to inhbit dopamine reuptake more than serotonin which would be a good balance for some who trying to recover from stimulant abuse of anykind. It has helped me alot, especially with consequences of ill-motivation and confused and drowzy state due to DA and norepinephrine depletion. Nothing phenominal just a little easier to focus, and generally move through the day much easier then anything has helped me w/o using amphetamines. I feel like even off adderall after supplementing with this extract just something I had long forgotten a seemingly close to normal dopamine system which blew away a long time ago. As with every thing that seems to good to be true, especially drugs the effect prolly won't last very long but hopefully i've built up some DA/5-HTP so I'll be able to get through the day atleast 40% easier wit no amps. rather than 10. Also I'm not naive in dealng wth these issues I've tried wellbutrin=pure anxiety, a little extra focus, l-dopa, l-tyrosine, provigl(useful with acute withdrawal) and hosts of others anyways sry for all this wall of text #adderall problems lol
8o8o
 
The original use of this herb(diadzin) is as a Chinese herbal treatment for moderating the consumption of ethanol. Although, after reading up on this almost unheard of herb, from what I can find it acts as a mild ALDH-2 inhibtor. ALDH-2 happens to be a essential enzyme involved in metabolism of DA and 5-HT, but not on the level of an actual full MAO inhibitor. It's much more tolerated, and milder than a persription MAO inhibitor. Diadzin is comparable but has much less of the draw backs, an a actual nootropic effect. Anyway it supposidly tends to inhbit dopamine reuptake more than serotonin which would be a good balance for some who trying to recover from stimulant abuse of anykind. It has helped me alot, especially with consequences of ill-motivation and confused and drowzy state due to DA and norepinephrine depletion. Nothing phenominal just a little easier to focus, and generally move through the day much easier then anything has helped me w/o using amphetamines. I feel like even off adderall after supplementing with this extract just something I had long forgotten a seemingly close to normal dopamine system which blew away a long time ago. As with every thing that seems to good to be true, especially drugs the effect prolly won't last very long but hopefully i've built up some DA/5-HTP so I'll be able to get through the day atleast 40% easier wit no amps. rather than 10. Also I'm not naive in dealng wth these issues I've tried wellbutrin=pure anxiety, a little extra focus, l-dopa, l-tyrosine, provigl(useful with acute withdrawal) and hosts of others anyways sry for all this wall of text #adderall problems lol
8o8o


BUMP hey mods can someone move this to ADD i made this thread along time ago, and just stumbled upon it again, and am curious to BL's insight on this
 
Agreed! mind posting the studies you read this from though? It makes it much easier for us to interpret lol
Also, for the love of your god don't drink on this stuff! ALDH-2 inhibition + booze= insta-hangover
 
Ah the bad thing is i need to research thsi some more as I originally read the study about a year ago. I'll get back to you on this, I think its very interesting. Also, thanks for the tip now you say that, thats is a great way to potentiate the negative hangover symptoms of acute alcohol w/d.
 
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