I didn't went in that deep to 3d model it, really just a random molecule. I was thinking of those big polypeptide compounds and stuff like Semax and if one could make similar stuff with pregabalin. After all it's just an amino acid, so basically you should be able to do most things that you can with other amino acids, too?
I guess those esters and even carbamate conjugations of different drugs would probably be already banned by most analogue acts in the US and Europe, otherwise it would be too simple and obvious to not have been done yet, as I can't see any big problems or overly dangerous uncertainties arising from using such methods. At least I would feel somewhat safer ingesting an ester or carbamate of two known drugs instead of those really crazy analogue (d)evolutions we have seen over the years, especially with cannabinoids it's getting into really strange territories and those cathinones are getting quite creepy, too.
Although I could imagine that some compounds could have new effects on their own and in the worst case you could end up with some unexpectectly high potent agonist or antagonist, or toxic lactames and other alterations, and even just slight differences in metabolism leaving a hydroxyl instead of an amide could result in much more toxic compounds as it's the case with phenibut vs. "phenibot", which is phenyl-GHB and can cause convulsions at low doses (the compound is on the european market and can be researched if anyone dares)
If a 1:1 ratio of odT : pregabalin wouldn't fit for someone than maybe a 1:2 ratio will do ^^ and it doesn't have to be the perfect substance in terms of recreational value, but having something relatively nice at all would be good enough in todays conditions, and the line between self medication, supplementing, self-improvement/neurohacking and recreation gets more blurry anyways, so compounds of all kinds are interesting I'd say, just depends on how many people would research them and how complicated they are to create.

I guess those esters and even carbamate conjugations of different drugs would probably be already banned by most analogue acts in the US and Europe, otherwise it would be too simple and obvious to not have been done yet, as I can't see any big problems or overly dangerous uncertainties arising from using such methods. At least I would feel somewhat safer ingesting an ester or carbamate of two known drugs instead of those really crazy analogue (d)evolutions we have seen over the years, especially with cannabinoids it's getting into really strange territories and those cathinones are getting quite creepy, too.
Although I could imagine that some compounds could have new effects on their own and in the worst case you could end up with some unexpectectly high potent agonist or antagonist, or toxic lactames and other alterations, and even just slight differences in metabolism leaving a hydroxyl instead of an amide could result in much more toxic compounds as it's the case with phenibut vs. "phenibot", which is phenyl-GHB and can cause convulsions at low doses (the compound is on the european market and can be researched if anyone dares)
If a 1:1 ratio of odT : pregabalin wouldn't fit for someone than maybe a 1:2 ratio will do ^^ and it doesn't have to be the perfect substance in terms of recreational value, but having something relatively nice at all would be good enough in todays conditions, and the line between self medication, supplementing, self-improvement/neurohacking and recreation gets more blurry anyways, so compounds of all kinds are interesting I'd say, just depends on how many people would research them and how complicated they are to create.

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