• N&PD Moderators: Skorpio | someguyontheinternet

Ketamine salts solubility

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The Spice Girls' Series:

1-(4,5-methylenedioxyindole-3-yl)-2-(dimethylamino)ethane.png


AMBER
1-(4,5-methylenedioxyindole-3-yl)-2-(dimethylamino)ethane

1-(5,6-methylenedioxyindole-3-yl)-2-(dimethylamino)ethane.png


SHANA
1-(5,6-methylenedioxyindole-3-yl)-2-(dimethylamino)ethane

1-(6,7-methylenedioxyindole-3-yl)-2-(dimethylamino)ethane.png


RACHEL
1-(6,7-methylenedioxyindole-3-yl)-2-(dimethylamino)ethane

The Spice Is Right!
 
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I have been 3 or 4 months without street speed or weed. And I got this funny, gnawing feeling that I’ve been sober over my limit so don’t touch me, cuz I’m electric, and if you touch you’ll get SHOCKED.
 
What do you guys think about INDOL-2-YL-N,N-dimethyl-ethanamine?
inadan-2-yl-dmt.jpg
 
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How about this one? Does it overlay 5-meo-dmt enough to be active?
3-meo-5tyl.jpg


How about 3-MeO-5-API. Should overlay with 5-MeO-aMT?
3-meo-5-API.jpg
 
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How about these? It's an indole with similar features to aminorex.
tryptanorex.jpg



psiocinorex.jpg


5-meo-tryptanorex.jpg
 
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Given that birch reduction of ephedrine (shake and bake method, Lithium/Liquid ammonia method) does not produce methamphetamine but instead purportedly produces 1-(1,4-cyclohexadien-1-yl)-N-methyl-2-propanamine which is halfway between propylhexedrine and methamphetamine, I am curious about ring substituted 1-(1,4-cyclohexadien-1-yl)-N-methyl-2-propanamines. People seem to like this drug and it is sold as methamphetamine.
shake-and-bake.jpg


Could this one be the next mephedrone for real?
4-mmc-reduced.jpg


Is this rigid enough to act as MDMA would?
MDMA-reduced.jpg


How about DOx analogs?
DOC-reduced.jpg
 
Wow.

Ok so this exists and is fairly potent
ZC-B (3-(4-bromo-2,5-dimethoxyphenyl)azetidine)
WO2021-0137908-1_structure.png


That's got me wondering if the azetidine of MDA would be feasible. Like would this likely resemble MDA in effects?
MDPA.jpg
 
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Is 3-phenylazetidine a stimulant?

I can find nothing indicating that it's ever been trialed. I found a paper about some ring substituted 3-phenylazetidines and the paper said that they were D3 agonists.

3-phenylazetidine.jpg
 
None of the indoles or pseudoindolws will work.

Aromatics are important for binding. Not only are they planer & lipophilic but they also have pi bonds. People have made meth with cyclohexane replacing benzene - MUCH less active. If you tried it with MDMA, the MD ring wouldn't be planer.

Others have been made.



Please check PubChem. It's free, takes a moment, avoids people declaring that they have 'invented' a new compound (in spite of having no idea how to make it( and most importantly because if you WANT to get better, reading all of the papers and references on PubChem is the way to go.

I'm always willing to help people improve their knowledgebase, but It's a labour to have to constantly correct when the answers are already on a free online database.

BTW I've been begging BL to support SMILES format so we can go IUPAC<->SMILES<->Image instantly. A HUGE benefit to us all.
 
None of the indoles or pseudoindolws will work.

Aromatics are important for binding. Not only are they planer & lipophilic but they also have pi bonds. People have made meth with cyclohexane replacing benzene - MUCH less active. If you tried it with MDMA, the MD ring wouldn't be planer.

Others have been made.



Please check PubChem. It's free, takes a moment, avoids people declaring that they have 'invented' a new compound (in spite of having no idea how to make it( and most importantly because if you WANT to get better, reading all of the papers and references on PubChem is the way to go.

I'm always willing to help people improve their knowledgebase, but It's a labour to have to constantly correct when the answers are already on a free online database.

BTW I've been begging BL to support SMILES format so we can go IUPAC<->SMILES<->Image instantly. A HUGE benefit to us all.
Wow...
They even went as far as ring substituted 3-phenylazetidine-NBOMe's and the 3-phenylazetadine-fly series.

This ccould be a rich patent for the rc market.
 
With mushrooms now being legal in some US cities, it's quite possible that the indoles have been 'saved' because they are such useful medicines and because the CSA act would make 100s of labs require security (very costly).

I will simply repeat that 7-methyl AMT is an excellent compound IF you are working at a large scale. An entactogen at lower doses only becoming trippy at a higher dose. I mean, we made it, we tested it. So we know it's good stuff.... but the Chinese wanted too much for the 7-methyl indole-3-carbaldehyde.

The secret is that AMT and thus 7-methyl AMT are chiral. One isomer has 5HT2a affinity, one is a triple releaser/reuptake inhibitor. The 2 isomers have TOTALLY different actions.
 
N-allyl-1-(3-methylphenyl)-1-methoxy-2-aminopropane.png


JESSY_JAMES
N-allyl-1-(3-methylphenyl)-1-methoxy-2-aminopropane

1-(3-methylphenyl)-2-aminopropane.png


TONY
1-(3-methylphenyl)-2-aminopropane

1-(3-methylphenyl)-2-ethylamino-1-oxopropane.png


CAREY
1-(3-methylphenyl)-2-ethylamino-1-oxopropane
 
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