Misc Ketamine + Anti-psychotic combination

[jobe28]

Anyone have any info about mixing Ketamine with Anti-psychotics (specifically "Clozapine").

I cant find too many definitive answers on google.

 

[Darksidesam]

why are you on anti-psychotics?

If for Schizophrenia, don't fuck around with ketamine and the likes, as its the same pathway, dont use NDMA antagonists like DXM, Ketamine or Methoxetamine.

If your not on anti psychotics i wouldnt reccomend mixing the 2 'for fun'
i dont find anti psychotics fun i find them very sedating and boring, as they are meant for very mentally sick people, they can be used for manic depression too.

 

[jobe28]

Well im on anti-psychotics at the moment..

What is this pathway youre talking about. What sortve negative effects would i experience? Are we talking like brain-damage? Or would it trigger psychosis?

 

[Toz]

NMDA antagonists have been used to mimic schizophrenia in studies if I remember reading correctly. This would lead me to believe they may very well lead to an excacerbation of psychotic symptoms.

Here's some reading that I'm not gonna get into because it doesn't concern me http://en.wikipedia.org/wiki/Glutamate_hypothesis_of_schizophrenia

 

[jobe28]

NMDA antagonists have been used to mimic schizophrenia in studies if I remember reading correctly. This would lead me to believe they may very well lead to an excacerbation of psychotic symptoms.

Can you remember where you read that. Id be interested to read about it.

 

[Toz]

^ updated my previous post with http://en.wikipedia.org/wiki/Glutamate_hypothesis_of_schizophrenia

 

[jobe28]

From what i see, ketamine may reproduce similar symptoms to schizophrenia, but only in the short-term.

And the combination of ketamine and anti-psychotics is going to just block the effects of Ketamine.

Meaning I probably wouldnt feel anything after doing the ketamine, and I might temporarily see symptoms of schizophrenia emerge.

Would that be accurate. Or does anyone else have any other important info regarding this combo?

 

[Lopez]

the combo would kill your buzz, sedate the crap out of you, and just make you pass out.

you'd feel little from the ketamine.

unfortunately same thing happens with benzo's and nmda antagonists, this i'm not sure why.

if you're suffering from schizophrenia, refrain from using any hallucinogens. suffering from temporal lobe epilepsy sucks, at one point i tried lsa and i literally felt like i was suffering an eternal hell in every living second. it was traumatizing.

mental disorders and hallucinogens don't mix..

 

[Psychedelic Jay]

You run the risk for bodily temperature problems and other inhumane self punishment if you do this...

Stay away from these types of drugs on anti-psychotics.

This is the reason why they stopped giving anti-psychotics to dissociative drug patients and started giving benzodiazepines instead in hospitals...

They were making burning up vegetables...

It causes more problems than it solved.