Keeping D-amp Tolerance Low - Larger Initial Dose or Redosing?

[ErgicMergic]

I am taking D-amp to treat ADD, and while it does a fantastic job of attenuating symptoms, the effects last far too short of a duration. I know most people take 10mg three times a day, but I want to hold off on something like that if I can help it.

I was wondering, is it better to take a larger initial dose (in my case 10mg)? Or is it better to take a mild initial dose (5-7.5mg) and take another half dose (2.5-3.75mg) two hours later?

I've read that although D-amp effects diminish at the 4-6 mark, it is still in the system at significant levels, and the booster dose should be about 50% of the initial dose.

I'm not looking to get high, just looking to extend the duration on a short-acting medication.

 

[Epsilon Alpha]

Well stims require escalating doses to maintain therapeutic effects thoughout the day, so my $0.02 would be to take the smallest effective initial dose then slowly work up or re-dose as needed. Try looking into mixed salts like Adderall though, there is a lot of science behind the formulation.

 

[ErgicMergic]

Adderall doesn't come in an instant release formation, though. Even the "IR" tablets are intermediate release: each of the four salts release at different times. Wouldn't that raise tolerance very quickly, compared to a single peak and drop of a Dexamphetamine Sulfate?

If I were going the intermediate/extended release route, I would much rather go with the Dexedrine Spansules, as they release 50% of the dose at once, and the rest gradually over a few hours. Adderall XR is bimodal, releasing 50% at once, and the other 50% 4 hours later. Plus, Adderall has that pesky L-amp in it My cervical disc pain's already pretty out of control as is, without the added neck tension from L-amp.

 

[weekend addiction]

Vyvanse is the answer!

 

[ErgicMergic]

I've read some lukewarm reviews on Vyvanse, how it releases (rather, breaks off L-Lysine) too slowly and is too subtle for effectiveness as a result. Have you had personal experience with it or Dex? Besides, I don't need 12-14 hours of medications, maybe 8 at the most. I would prefer taking the 12 hour duration of 30mg Vyvanse, and compressing it in to an equivalent 10mg Dexedrine IR/Spansule duration.

How do I go about dosing 10mg Dexedrine effectively over 6-8 hours? A single 10mg spansule releases 5mg immediately (beads coated in glucose), and the other 5mg gradually over a few hours (polystirex beads), which sounds perfect. Maybe I can emulate that with IR tabs by taking 5mg, then 2.5-5mg at t+2:00?

And Epsilon Alpha, I am only looking for 6-8 hours of effectiveness, not all day ADD effectiveness. I feel like the less time my brain is releasing dopamine, the less dependent I'll get on amphetamine? I want to be able to stop taking amphetamine whenever I want and walk away without anhedonia, lack of motivation, fatigue, etc. Basically my old self before I ever took an amphetamine (one month ago). I've never abused it, and won't, just looking for good ADD relief for reading, homework, and studying.

 

[weekend addiction]

Yes I have lots of experience with vyvanse and adderall. Only a couple with dexedrine though. But I love vyvanse it doesn't have a peak or a drop off point that is noticeable. It's perfect for ADD and drug addicts aren't big fans of it so its easy to get a script. The people who don't like it are often either looking for a high or looking for a large dose of AMP. Just try it if you don't like it you don't have to take it. If your really looking to treat your add with dex then atleast look into it for yourself don't let others tell you what works for you.

EDIT: just read your post and trust me vyvanse is less addicting!

 

[Renz Envy]

Yes vyvanse, in my opinion, is great for an individual trying to get some studying done in a 6-8 hour time period and go to bed on time. The come down is fairly smooth in its therapeutic dose and taking a little caffeine usually brings me back to "speed".

Dexedrine and adderall can still be a bit "harsh" in my opinion, but it's all up to the user's metabolism.

 

[opiatekrzy]

haha, when i take my initial dose of adderall (60mg) on average, i always take half of that dose when it wears off after 3-4 hours, when i feel the crash come on, i redose with half of my initial dose, to avoid crash, and still extend the high without causing negative side effects, when the 2nd dose wears off, i take half of that 3-4 hours later (15mg)...i still crash but not as bad, and usually pop a klonopin after and eat some food...i used to take 80-120mg of adderall for an initial dose, but its a recipe for disaster and leads to a bunch of problems, ugly road to go down, when i was 14yrs old i used to take 400mg a day, but being wiser and ten years later, i never dose abose 60mg of adderall, if i do any higher im asking for a negative high

 

[Pjkt2501]

OP, I think for your needs an interests, as someone else has mentioned, you want to use the smallest possible (effective) initial dose, and then re-dose lightly throughout the day, as needed.

Each of the different (amphetamine) salts is working on the same receptors in your brain, and as such will create tolerance all the same / have cross tolerances.